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We present a new method, called "forced-spectrum fitting", for physically-based spectral modelling of radio sources during deconvolution. This improves upon current common deconvolution fitting methods, which often produce inaccurate…
Pathologies associated with calcified tissue, such as osteoporosis, demand in vivo and/or in situ spectroscopic analysis to assess the role of chemical substitutions in the inorganic component. High energy X-ray or NMR spectroscopies are…
This paper presents a novel approach for computing substructure characteristic modes. This method leverages electromagnetic scattering matrices and spherical wave expansion to directly decompose electromagnetic fields. Unlike conventional…
Fluorescence fluctuation spectroscopy is applied to study molecules, passing through a small observation volume, usually subjected to diffusive or convective motion in liquid phase. We suggest that such a technique could be used to measure…
Reversible photodegradation is a process that has been observed in several dye molecules, but the underlying mechanisms are not still well understood. In this contribution, we characterize a series of anthraquinone dyes to determine how…
Populations of heterogeneous cells play an important role in many biological systems. In this paper we consider systems where each cell can be modelled by an ordinary differential equation. To account for heterogeneity, parameter values are…
Recent advances in cancer research largely rely on new developments in microscopic or molecular profiling techniques offering high level of detail with respect to either spatial or molecular features, but usually not both. Here, we present…
A fundamental question about the nature of quantum materials such as High-T$_c$ systems remain open to date -- it is unclear whether they are (some variety of) Fermi liquids, or (some variety of) non Fermi liquids. A direct avenue to…
In this study, we investigate the inverse source problem arising in bioluminescence tomography, the objective of which is to reconstruct both the support and the intensity of an internal light source from boundary measurements governed by…
Fluorescence Molecular Tomography (FMT) is a promising technique for non-invasive 3D visualization of fluorescent probes, but its reconstruction remains challenging due to the inherent ill-posedness and reliance on inaccurate or…
Texture can be defined as the change of image intensity that forms repetitive patterns, resulting from physical properties of the object's roughness or differences in a reflection on the surface. Considering that texture forms a complex…
Protein rotational kinetics are essential for understanding macromolecular behavior in crowded environments, yet measuring these dynamics at solid-liquid interfaces remains a significant challenge due to low signal strengths. Here, we…
Wavelet transform of polarized fluorescence spectroscopic data of human breast tissues is found to reliably differentiate normal and malignant tissue types and isolate characteristic biochemical signatures of cancerous tissues, which can…
Wavelet transform of polarized fluorescence spectra of human breast tissues is found to localize spectral features that can reliably differentiate normal and malignant tissue types. The intensity differences of parallel and perpendicularly…
We derive the statistics of the signals generated by shape fluctuations of large molecules studied by feedback tracking microscopy. We account for the influence of intramolecular dynamics on the response of the tracking system, and derive a…
To illustrate the power of the biophysical approach in solving important problems in life science, I present here one of our current research projects as an example. We have developed special biophotonic techniques to study the dynamic…
Spectral properties of fluorescent radiation from a two-level quantum system with broken inversion spatial symmetry, which can be described by a model of an one-electron two-level atom whose electric dipole moment operator has permanent…
We present a feature-resolved methodology to analyse the photoluminescence dynamics of single emitters using a combination of lifetime, spectral, and photon correlation analyses. By integrating conventional ensemble photon statistics…
The combination of different imaging modalities into single imaging platforms has a strong potential in biomedical sciences since it permits the analysis of complementary properties of the target sample. Here, we report on an extremely…
Medical ultrasound provides images which are the spatial map of the tissue echogenicity. Unfortunately, an ultrasound image is a low-quality version of the expected Tissue Reflectivity Function (TRF) mainly due to the non-ideal Point Spread…