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Tree structures appear in many fields of the life sciences, including phylogenetics, developmental biology and nucleic acid structures. Trees can be used to represent RNA secondary structures, which directly relate to the function of…

Machine Learning · Computer Science 2026-01-22 Pengyu Liu , Mariel Vázquez , Nataša Jonoska

Tree comparison metrics have proven to be an invaluable aide in the reconstruction and analysis of phylogenetic (evolutionary) trees. The path-length distance between trees is a particularly attractive measure as it reflects differences in…

Data Structures and Algorithms · Computer Science 2018-11-05 David Bryant , Celine Scornavacca

We define, analyze, and give efficient algorithms for two kinds of distance measures for rooted and unrooted phylogenies. For rooted trees, our measures are based on the topologies the input trees induce on triplets; that is, on…

Data Structures and Algorithms · Computer Science 2009-06-30 Mukul S. Bansal , Jianrong Dong , David Fernández-Baca

Phylogenetic trees summarize evolutionary relationships between organisms, and tools to analyze collections of phylogenetic trees enable contrasts between different genes' ancestry. The BHV metric space has enabled the analysis of…

Quantitative Methods · Quantitative Biology 2026-04-24 Maria Alejandra Valdez Cabrera , Amy D Willis

In evolutionary biology, phylogenetic networks are constructed to represent the evolution of species in which reticulate events are thought to have occurred, such as recombination and hybridization. It is therefore useful to have…

Populations and Evolution · Quantitative Biology 2017-03-16 Vincent Moulton , James Oldman , Taoyang Wu

We propose a novel method for the inference of phylogenetic trees that utilises point configurations on hyperbolic space as its optimisation landscape. Each taxon corresponds to a point of the point configuration, while the evolutionary…

Machine Learning · Computer Science 2021-06-07 Benjamin Wilson

We consider the problem of estimating species trees from unrooted gene tree topologies in the presence of incomplete lineage sorting, a common phenomenon that creates gene tree heterogeneity in multilocus datasets. One popular class of…

Populations and Evolution · Quantitative Biology 2018-12-21 Sebastien Roch

Understanding the evolution of a set of genes or species is a fundamental problem in evolutionary biology. The problem we study here takes as input a set of trees describing {possibly discordant} evolutionary scenarios for a given set of…

Data Structures and Algorithms · Computer Science 2019-07-10 Cedric Chauve , Mark Jones , Manuel Lafond , Céline Scornavacca , Mathias Weller

More than ever, today we are left with the abundance of molecular data outpaced by the advancements of the phylogenomic methods. Especially in the case of presence of many genes over a set of species under the phylogeny question, more…

Applications · Statistics 2021-11-29 Ali Amiryousefi

It is possible to consider stochastic models of sequence evolution in phylogenetics in the context of a dynamical tensor description inspired from physics. Approaching the problem in this framework allows for the well developed methods of…

Populations and Evolution · Quantitative Biology 2007-05-23 J. G. Sumner , P. D. Jarvis

This paper introduces constNJ, the first algorithm for phylogenetic reconstruction of sets of trees with constrained pairwise rooted subtree-prune regraft (rSPR) distance. We are motivated by the problem of constructing sets of trees which…

Populations and Evolution · Quantitative Biology 2009-09-30 Frederick A. Matsen

Phylogenetic trees can be reconstructed from the matrix which contains the distances between all pairs of languages in a family. Recently, we proposed a new method which uses normalized Levenshtein distances among words with same meaning…

Computation and Language · Computer Science 2015-05-14 Filippo Petroni , Maurizio Serva

Phylogenetic trees are leaf-labelled trees used to model the evolution of species. In practice it is not uncommon to obtain two topologically distinct trees for the same set of species, and this motivates the use of distance measures to…

Data Structures and Algorithms · Computer Science 2026-03-24 David Mestel , Steven Chaplick , Steven Kelk , Ruben Meuwese

Merge trees are a common topological descriptor for data with a hierarchical component, such as terrains and scalar fields. The interleaving distance, in turn, is a common distance for comparing merge trees. However, the interleaving…

Computational Geometry · Computer Science 2025-01-13 Thijs Beurskens , Tim Ophelders , Bettina Speckmann , Kevin Verbeek

Phylogenetic tree reconstruction is traditionally based on multiple sequence alignments (MSAs) and heavily depends on the validity of this information bottleneck. With increasing sequence divergence, the quality of MSAs decays quickly.…

Populations and Evolution · Quantitative Biology 2011-01-11 Roland F. Schwarz , William Fletcher , Frank Förster , Benjamin Merget , Matthias Wolf , Jörg Schultz , Florian Markowetz

Recently there has been renewed interest in phylogenetic inference methods based on phylogenetic invariants, alongside the related Markov invariants. Broadly speaking, both these approaches give rise to polynomial functions of sequence site…

Quantitative Methods · Quantitative Biology 2017-03-31 Jeremy G Sumner , Amelia Taylor , Barbara R Holland , Peter D Jarvis

In this paper we examine the usefulness of two classes of algorithms Distance Methods, Discrete Character Methods (Felsenstein and Felsenstein 2003) widely used in genetics, for predicting the family relationships among a set of related…

Computation and Language · Computer Science 2014-01-06 Taraka Rama , Sudheer Kolachina , Lakshmi Bai B

Phylogenetic networks are a generalization of phylogenetic trees that are used in biology to represent reticulate or non-treelike evolution. Recently, several algorithms have been developed which aim to construct phylogenetic networks from…

Populations and Evolution · Quantitative Biology 2011-10-05 K. T. Huber , V. Moulton

The distance matrix of a dataset $X$ of $n$ points with respect to a distance function $f$ represents all pairwise distances between points in $X$ induced by $f$. Due to their wide applicability, distance matrices and related families of…

Data Structures and Algorithms · Computer Science 2022-10-28 Piotr Indyk , Sandeep Silwal

Phylogenetic networks are generalizations of trees that allow for the modeling of non-tree like evolutionary processes. Split networks give a useful way to construct networks with intuitive distance structures induced from the associated…

Combinatorics · Mathematics 2024-09-18 Bryson Kagy , Seth Sullivant