English
Related papers

Related papers: Sexual replication in the quasispecies model

200 papers

The evolution of microbial and viral organisms often generates clonal interference, a mode of competition between genetic clades within a population. In this paper, we show that interference strongly constrains the genetic and phenotypic…

Populations and Evolution · Quantitative Biology 2019-06-12 Torsten Held , Daniel Klemmer , Michael Lässig

Using Monte Carlo model of biological evolution we have discovered that populations can switch between two different strategies of their genomes' evolution; Darwinian purifying selection and complementing the haplotypes. The first one is…

Populations and Evolution · Quantitative Biology 2009-11-13 Marta Zawierta , Wojciech Waga , Dorota Mackiewicz , Przemyslaw Biecek , Stanislaw Cebrat

Using a bit string model, we show that asexual reproduction for diploids is more efficient than for haploids: it improves genetic material producing new individuals with less deleterious mutations. We also see that in a system where…

Statistical Mechanics · Physics 2009-11-07 Armando Ticona , Paulo Murilo C. de Oliveira

We examine a model of biological evolution of Eigen's quasispecies in a holey fitness landscape, where the fitness of a site is either 0 (lethal site) or a uniform positive constant (viable site). So, the evolution dynamics is determined by…

Statistical Mechanics · Physics 2016-08-16 Michal Kolář , František Slanina

We present a mathematical simplification for the evolutionary dynamics of a heritable trait within a two-sex population. This trait is assumed to control the timing of sex-specific life-history events, such as the age of sexual maturity and…

Populations and Evolution · Quantitative Biology 2019-07-04 M. H. Chan , K. Hawkes , P. S. Kim

Using a bit-string model of evolution, we find a successful route to diploidy and sex in simple organisms. Allowing the sexually reproducing diploid individuals to also perform mitosis, as they do in a haploid-diploid cycle, leads to the…

Soft Condensed Matter · Physics 2007-05-23 Erkan Tuzel , Volkan Sevim , Ayse Erzan

We introduce a new parameter to discuss the behavior of a genetic algorithm. This parameter is the mean number of exact copies of the best fit chromosomes from one generation to the next. We argue that the genetic algorithm should operate…

Neural and Evolutionary Computing · Computer Science 2015-12-04 Raphaël Cerf

We introduce a generalization of the parallel, or Crow-Kimura, and Eigen models of molecular evolution to represent the exchange of genetic information between individuals in a population. We study the effect of different schemes of genetic…

Populations and Evolution · Quantitative Biology 2009-11-13 Enrique Munoz , Jeong-Man Park , Michael W. Deem

Mechanisms leading to speciation are a major focus in evolutionary biology. In this paper, we present and study a stochastic model of population where individuals, with type a or A, are equivalent from ecological, demographical and spatial…

Populations and Evolution · Quantitative Biology 2017-04-20 Camille Coron , Manon Costa , Hélène Leman , Charline Smadi

In large populations, multiple beneficial mutations may be simultaneously spreading. In asexual populations, these mutations must either arise on the same background or compete against each other. In sexual populations, recombination can…

Populations and Evolution · Quantitative Biology 2013-12-19 D. B. Weissman , O. Hallatschek

A population genetics formulation of Eigen's molecular quasispecies model is proposed and several simple replication landscapes are investigated analytically. Our results show a remarcable similarity to those obtained with the original…

Condensed Matter · Physics 2009-10-28 Domingos Alves , Jose Fernando Fontanari

Using a lattice model based on Monte Carlo simulations, we study the role of the reproduction pattern on the fate of an evolving population. Each individual is under the selection pressure from the environment and random mutations. The…

Statistical Mechanics · Physics 2009-11-10 Mingfeng He , Hongbo Ruan , Changliang Yu , Lei Yao

Homologous recombination is an important operator in the evolution of biological organisms. However, there is still no clear, generally accepted understanding of why it exists and under what circumstances it is useful. In this paper we…

Populations and Evolution · Quantitative Biology 2013-08-12 Manuel Beltrán del Río , Christopher R. Stephens , David A. Rosenblueth

We study a continuous-time dynamical system that models the evolving distribution of genotypes in an infinite population where genomes may have infinitely many or even a continuum of loci, mutations accumulate along lineages without…

Populations and Evolution · Quantitative Biology 2009-02-03 Aubrey Clayton , Steven N. Evans

In its initial form, the expensive son hypothesis postulates that sons from male-biased sexually dimorphic species require more food during growth than daughters, which ultimately incur fitness costs for mothers predominantly producing and…

Populations and Evolution · Quantitative Biology 2024-12-13 Lucas Invernizzi , Jean-françois Lemaître , Mathieu Douhard

Intragenomic recombination (crossover) is a very important evolutionary mechanism. The crossover events are not evenly distributed along the natural chromosomes. Monte Carlo simulations revealed that frequency of recombinations decides…

Genomics · Quantitative Biology 2009-01-13 Wojciech Waga , Marta Zawierta , Jakub Kowalski , Stanislaw Cebrat

Quasispecies theory provides the conceptual and theoretical bases for describing the dynamics of biological information of replicators subject to large mutation rates. This theory, initially conceived within the framework of prebiotic…

Populations and Evolution · Quantitative Biology 2025-06-26 Edward A. Turner , Francisco Crespo , Josep Sardanyés , Nolbert Morales

We consider a population of haploid individuals reproducing sexually, i.e. for which the genome of each individual is a random mixture of the genome of its two parents. We assume that initially one individual carries a mutation at one…

Probability · Mathematics 2022-10-06 Camille Coron , Yves Le Jan

We study the large population limit of a stochastic individual-based model which describes the time evolution of a diploid hermaphroditic population reproducing according to Mendelian rules. In [Neukirch, Bovier, 2016] it is proved that…

Probability · Mathematics 2018-01-23 Anton Bovier , Loren Coquille , Rebecca Neukirch

Much has been debated about the benefit of sexual over asexual reproduction in terms of evolutionary fitness. Here we focus on the advantage that may be brought about by the process of mating, where the choosing of mates contributes to the…

Populations and Evolution · Quantitative Biology 2007-05-23 Wan Ahmad Tajuddin Wan Abdullah