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This paper aims at identifying the information flow in state-of-the-art machine translation systems, taking as example the transfer of gender when translating from French into English. Using a controlled set of examples, we experiment…

Computation and Language · Computer Science 2022-02-28 Guillaume Wisniewski , Lichao Zhu , Nicolas Ballier , François Yvon

The RNA inverse folding problem, a key challenge in RNA design, involves identifying nucleotide sequences that can fold into desired secondary structures, which are critical for ensuring molecular stability and function. The inherent…

Computer Vision and Pattern Recognition · Computer Science 2025-12-04 Guang Yang , Lei Fan

Motivation: LTR retrotransposons are mobile elements that are able, like retroviruses, to copy and move inside eukaryotic genomes. In the present work, we propose a branching model for studying the propagation of LTR retrotransposons in…

Cell Behavior · Quantitative Biology 2016-03-08 Serge Moulin , Nicolas Seux , Stéphane Chrétien , Christophe Guyeux , Emmanuelle Lerat

We investigate the number of inverted repeats observed in 37 complete genomes of bacteria. The number of inverted repeats observed is much higher than expected using Markovian models of DNA sequences in most of the eubacteria. By using the…

Statistical Mechanics · Physics 2007-05-23 Fabrizio Lillo , Salvatore Basile , Rosario N. Mantegna

Interactions are ubiquitous across biological systems. These interactions can be abstracted as patterns of connections among distinct units such as genes, proteins, individual organisms, or species which form a hierarchy of biological…

Populations and Evolution · Quantitative Biology 2018-09-18 Pierre-Olivier Montiglio , Kiyoko M. Gotanda , Claudius F. Kratochwil , Kate L. Laskowski , Carey D. Nadell , Damien R. Farine

The effects of the residual proton-neutron interactions on bandcrossing features are studied by means of shell model calculations for nucleons in a high-j intruder orbital. The presence of an odd-nucleon shifts the frequency of the…

Nuclear Theory · Physics 2009-10-31 S. Frauendorf , J. A. Sheikh

State-of-the-art named entity recognition (NER) systems have been improving continuously using neural architectures over the past several years. However, many tasks including NER require large sets of annotated data to achieve such…

Machine Learning · Computer Science 2020-01-22 Parminder Bhatia , Kristjan Arumae , Busra Celikkaya

We present a novel topological classification of RNA secondary structures with pseudoknots. It is based on the topological genus of the circular diagram associated to the RNA base-pair structure. The genus is a positive integer number,…

Biomolecules · Quantitative Biology 2007-05-23 Michael Bon , Graziano Vernizzi , Henri Orland , A. Zee

We introduce the software tool NTRFinder to find the complex repetitive structure in DNA we call a nested tandem repeat (NTR). An NTR is a recurrence of two or more distinct tandem motifs interspersed with each other. We propose that nested…

Quantitative Methods · Quantitative Biology 2011-05-04 A. A. Matroud , M. D. Hendy , C. P. Tuffley

The set of regulatory interactions between genes, mediated by transcription factors, forms a species' transcriptional regulatory network (TRN). By comparing this network with measured gene expression data one can identify functional…

Molecular Networks · Quantitative Biology 2015-05-19 Carsten Marr , Fabian J. Theis , Larry S. Liebovitch , Marc-Thorsten Hütt

We present Brownian dynamics simulations of the facilitated diffusion of a protein, modelled as a sphere with a binding site on its surface, along DNA, modelled as a semi-flexible polymer. We consider both the effect of DNA organisation in…

Biological Physics · Physics 2012-12-10 C. A. Brackley , M. E. Cates , D. Marenduzzo

Patchy particles have received great attention due to their ability to develop directional and selective interactions and serve as building units for the self-assembly of innovative colloidal molecules and crystalline structures. Although…

Soft Condensed Matter · Physics 2023-01-16 Rawan Khalaf , Andrea Viamonte , Etienne Ducrot , Rémi Mérindol , Serge Ravaine

Several recent studies show that companion cells in flowering plant gametophytes relax epigenetic control of transposable elements (TEs) to promote production of small RNA that presumably assist nearby reproductive cells in management of…

Populations and Evolution · Quantitative Biology 2013-10-31 John D. Laurie

We present Transfer Orthology Networks (TRON), a novel neural network architecture designed for cross-species transfer learning. TRON leverages orthologous relationships, represented as a bipartite graph between species, to guide knowledge…

Machine Learning · Computer Science 2025-10-20 Vikash Singh

Gene essentiality refers to the degree to which a gene is necessary for the survival and reproductive efficacy of a living organism. Although the essentiality of non-coding genes has been documented, there are still aspects of non-coding…

Molecular Networks · Quantitative Biology 2023-09-20 Hanlin Zhang , Wenzheng Cheng

MicroRNAs (miRNAs) are small non-coding RNAs which regulate gene expression by binding to the 3' UTR of the corresponding messenger RNAs. We construct miRNA co-target networks for 22 different species using a target prediction database,…

Molecular Networks · Quantitative Biology 2013-07-05 Mahashweta Basu , Nitai P. Bhattacharyya , P. K. Mohanty

We consider a one-dimensional (1D) structure where non-interacting spin-$s$ scattering centers, such as quantum impurities or multi-level atoms, are embedded at given positions. We show that the injection into the structure of unpolarized…

Quantum Physics · Physics 2010-04-30 Francesco Ciccarello , Sougato Bose , Michelangelo Zarcone

Experimental evidences show that in gene transcription, RNA polymerase has the possibility to be stalled at certain position of the transcription template. This may be due to the template damage, or protein barriers. Once stalled,…

Biological Physics · Physics 2015-02-10 Jingwei Li , Yunxin Zhang

Transcription is one of the essential processes for cells to read genetic information encoded in genes, which is initiated by the binding of RNA polymerase to related promoter. Experiments have found that the nucleotide sequence of promoter…

Genomics · Quantitative Biology 2015-03-13 Jingwei Li , Yunxin Zhang

Research shows that gene duplication followed by either repurposing or removal of duplicated genes is an important contributor to evolution of gene and protein interaction networks. We aim to identify which characteristics of a network can…

Molecular Networks · Quantitative Biology 2021-07-27 Peter Crawford-Kahrl , Robert R. Nerem , Bree Cummins , Tomas Gedeon