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To understand the effect of assortative mating on the genetic evolution of a population, we consider a finite population in which each individual has a type, determined by a sequence of n diallelic loci. We assume that the population…

Probability · Mathematics 2023-11-30 Alison M. Etheridge , Sophie Lemaire

A model of mutation rate evolution for multiple loci under arbitrary selection is analyzed. Results are obtained using techniques from Karlin (1982) that overcome the weak selection constraints needed for tractability in prior studies of…

Populations and Evolution · Quantitative Biology 2013-02-04 Lee Altenberg

The accurate numerical solution of partial differential equations is a central task in numerical analysis allowing to model a wide range of natural phenomena by employing specialized solvers depending on the scenario of application. Here,…

Numerical Analysis · Mathematics 2022-12-13 Moritz Reh , Martin Gärttner

Consider a system evolving according to an absorbing discrete-time Markov chain with known transition matrix. The state of the system is observed at two points in time, separated by an unknown number of generations. We are interested in…

Probability · Mathematics 2015-11-04 Bianca De Sanctis , A. P. Jason de Koning

Kolmogorov complexity and algorithmic probability are defined only up to an additive resp. multiplicative constant, since their actual values depend on the choice of the universal reference computer. In this paper, we analyze a natural…

Information Theory · Computer Science 2010-03-29 Markus Mueller

The purpose of this paper is to develop a new effective approach to higher-order mixing in the semisimple setting. We prove effective exponential mixing of all orders for partially hyperbolic algebraic actions, under a strong spectral-gap…

Dynamical Systems · Mathematics 2026-05-21 Zhenqi Jenny Wang

Biological tools such as genetic lineage tracing, three dimensional confocal microscopy and next generation DNA sequencing are providing new ways to quantify the distribution of clones of normal and mutated cells. Population-wide clone size…

Quantitative Methods · Quantitative Biology 2013-11-25 Roshan A , Jones PH , Greenman CD

We solve the Chapman-Kolmogorov equation and study the exact splitting probabilities of the general stochastic process which describes polymer translocation through membrane pores within the broad class of Markov chains. Transition…

Statistical Mechanics · Physics 2015-05-19 Felipe Mondaini , L. Moriconi

We consider a class of nonlocal reaction-diffusion problems, referred to as replicator-mutator equations in evolutionary genetics. By using explicit changes of unknown function, we show that they are equivalent to the heat equation and,…

Analysis of PDEs · Mathematics 2020-12-16 Matthieu Alfaro , Rémi Carles

Consider a set of N agents seeking to solve distributively the minimization problem $\inf_{x} \sum_{n = 1}^N f_n(x)$ where the convex functions $f_n$ are local to the agents. The popular Alternating Direction Method of Multipliers has the…

Distributed, Parallel, and Cluster Computing · Computer Science 2014-12-30 Franck Iutzeler , Pascal Bianchi , Philippe Ciblat , Walid Hachem

Consider a haploid population of fixed finite size with a finite number of allele types and having Cannings exchangeable genealogy with neutral mutation. The stationary distribution of the Markov chain of allele counts in each generation is…

Probability · Mathematics 2016-12-09 H. L. Gan , Adrian Röllin , Nathan Ross

We analyse conditions for an evolution equation with a drift and fractional diffusion to have a Holder continuous solution. In case the diffusion is of order one or more, we obtain Holder estimates for the solution for any bounded drift. In…

Analysis of PDEs · Mathematics 2011-04-26 Luis Silvestre

Completion problems, of recovering a point from a set of observed coordinates, are abundant in applications to image reconstruction, phylogenetics, and data science. We consider a completion problem coming from algebraic statistics: to…

Statistics Theory · Mathematics 2024-12-04 May Cai , Cecilie Olesen Recke , Thomas Yahl

We study the large population limit of the Moran process, assuming weak-selection, and for different scalings. Depending on the particular choice of scalings, we obtain a continuous model that may highlight the genetic-drift (neutral…

Populations and Evolution · Quantitative Biology 2013-01-21 Fabio A. C. C. Chalub , Max O. Souza

The stable allocation problem is a many-to-many generalization of the well-known stable marriage problem, where we seek a bipartite assignment between, say, jobs (of varying sizes) and machines (of varying capacities) that is "stable" based…

Data Structures and Algorithms · Computer Science 2014-11-26 Ágnes Cseh , Brian C. Dean

In this article, discrete and stochastic changes in (effective) population size are incorporated into the spectral representation of a biallelic diffusion process for drift and small mutation rates. A forward algorithm inspired by…

Populations and Evolution · Quantitative Biology 2024-03-11 Lynette Caitlin Mikula , Claus Vogl

We study nonlinear stationary Kolmogorov equations with degenerate diffusion matrices and discontinuous coefficients. The existence of a solution is proved. We propose a new approach based on an integral condition with Lyapunov functions…

Analysis of PDEs · Mathematics 2026-04-21 Aziz M. Embarek , Dmitry V. Shatilovich

A strong demographic Allee effect in which the expected population growth rate is negative below a certain critical population size can cause high extinction probabilities in small introduced populations. However, many species are…

Populations and Evolution · Quantitative Biology 2013-11-22 Meike J. Wittmann , Wilfried Gabriel , Dirk Metzler

In this work, we show that for the martingale problem for a class of degenerate diffusions with bounded continuous drift and diffusion coefficients, the small noise limit of non-degenerate approximations leads to a unique Feller limit. The…

Probability · Mathematics 2022-03-01 Anugu Sumith Reddy , Vivek S. Borkar

We formulate an Alternating Direction Method of Mul-tipliers (ADMM) that systematically distributes the computations of any technique for optimizing pairwise functions, including non-submodular potentials. Such discrete functions are very…

Computer Vision and Pattern Recognition · Computer Science 2017-04-12 Jose Dolz , Ismail Ben Ayed , Christian Desrosiers
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