Related papers: Positioning Crenarchaeal tRNA-Introns
It has recently been realized that a general class of non-abelian defects can be created in conventional topological states by introducing extrinsic defects, such as lattice dislocations or superconductor-ferromagnet domain walls in…
We show that as in abelian gauge fields, nonabelian gauge fields are also trapped on a brane in the Randall-Sundrum model by applying a new mechanism based on topological Higgs mechanism. It is pointed out that although almost massless…
Background: It is necessary and essential to discovery protein function from the novel primary sequences. Wet lab experimental procedures are not only time-consuming, but also costly, so predicting protein structure and function reliably…
h-BCN is an intriguing material system where the bandgap varies considerably depending on the atomic configuration, even at a fixed composition. Exploring stable atomic configurations in this system is crucial for discussing the energetic…
Nucleic acids are highly deformable helical molecules constantly stretched, twisted and bent in their biological functioning. Single molecule experiments have shown that double stranded (ds)-RNA and standard ds-DNA have opposite…
Emerging high-throughput technologies have led to a deluge of putative non-coding RNA (ncRNA) sequences identified in a wide variety of organisms. Systematic characterization of these transcripts will be a tremendous challenge. Homology…
BACKGROUND: Transcriptional regulation is a key mechanism in the functioning of the cell, and is mostly effected through transcription factors binding to specific recognition motifs located upstream of the coding region of the regulated…
The prevalence of neutral mutations implies that biological systems typically have many more genotypes than phenotypes. But can the way that genotypes are distributed over phenotypes determine evolutionary outcomes? Answering such questions…
The statistical physics of homogeneous DNA is investigated by the imaginary time path integral formalism. The base pair stretchings are described by an ensemble of paths selected through a macroscopic constraint, the fulfillement of the…
Anomaly detection with only prior knowledge from normal samples attracts more attention because of the lack of anomaly samples. Existing CNN-based pixel reconstruction approaches suffer from two concerns. First, the reconstruction source…
Among its great findings, the IRAS mission showed the existence of an unidentified mid-IR feature around 21 um. Since its discovery, this feature has been detected in all C-rich proto-PNe of intermediate spectral type (A-G) and - weakly -…
Context- S stars are late-type giants with spectra showing characteristic molecular bands of ZrO in addition to the TiO bands typical of M stars. Their overabundance pattern shows the signature of s-process nucleosynthesis. Intrinsic,…
Exchange type chromosome aberrations (ETCAs) are rearrangements of the genome that occur when chromosomes break and the resulting fragments rejoin with other fragments from other chromosomes. ETCAs are commonly observed in cancer cells and…
Metagenomic binning aims to cluster DNA fragments from mixed microbial samples into their respective genomes, a critical step for downstream analyses of microbial communities. Existing methods rely on deterministic representations, such as…
S stars are transition objects between M-type giants and carbon stars on the asymptotic giant branch (AGB). They are characterized by overabundances of s-process elements. Roughly half of them are enhanced in technetium (Tc), an s-process…
Mirtrons are a special type of pre-miRNA which originate from intronic regions and are spliced directly from the transcript instead of being processed by Drosha. The splicing mechanism is better understood for the processing of mRNA for…
ds-RNA and standard ds-DNA show specific structural differences in their di-nucleotide steps, piled along the helical axis. Modeling the helices of short fragments by a 3D mesoscopic Hamiltonian model, I use path integral techniques to…
A single gene can encode for different protein versions through a process called alternative splicing. Since proteins play major roles in cellular functions, aberrant splicing profiles can result in a variety of diseases, including cancers.…
Sex chromosomes have evolved repeatedly across the Tree of Life, yet their evolutionary fates differ strikingly. In sharp contrast to mammals and birds with degenerated, stable Y/W chromosomes, in most amphibians, teleosts, non avian…
The structural parameters of alpha helix and some forms of DNA-structures are determined by methods of algebraic topology. These structures are locally periodic and correspond to the bifurcation point for minimal surfaces given by…