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The biochemical reaction networks that regulate living systems are all stochastic to varying degrees. The resulting randomness affects biological outcomes at multiple scales, from the functional states of single proteins in a cell to the…

In this study, deep learning is used to estimate kinetic parameters for modeling itaconic acid production based on real batch experiments conducted at different agitation speeds and reactor scales. Two deep learning strategies, namely…

Machine Learning · Computer Science 2026-04-27 Daria Fokina , Marco Baldan , Constantin Romankiewicz , Wolfgang Laudensack , Roland Ulber , Michael Bortz

An adpative integration technique for time advancement of particle motion in the context of coupled computational fluid dynamics (CFD) - discrete element method (DEM) simulations is presented in this work. CFD-DEM models provide an accurate…

Computational Physics · Physics 2018-02-28 Hariswaran Sitaraman , Ray Grout

Modeling of turbulent combustion system requires modeling the underlying chemistry and the turbulent flow. Solving both systems simultaneously is computationally prohibitive. Instead, given the difference in scales at which the two…

Machine Learning · Computer Science 2022-02-22 Amol Salunkhe , Dwyer Deighan , Paul DesJardin , Varun Chandola

Reaction systems are a computational model inspired by the bio-chemical reactions that happen inside biological cells. They have been and currently are studied for their many nice theoretical properties. They are also a useful modeling tool…

Formal Languages and Automata Theory · Computer Science 2020-08-05 Claudio Ferretti , Alberto Leporati , Luca Manzoni , Antonio E. Porreca

Numerical simulations underpin much fluid dynamics research today. Such simulations often rely on large scale high performance computing (HPC) systems, and have a significant carbon footprint. Increasing the efficiency of data centers or…

Physics and Society · Physics 2025-01-23 Miranda van Heel , Jack R. C. King

Computational fluid dynamics (CFD) is an important tool for the simulation of the cardiovascular function and dysfunction. Due to the complexity of the anatomy, the transitional regime of blood flow in the heart, and the strong mutual…

Battery thermal management system is an indispensable part of the electric vehicles working with Lithium-ion batteries. Accordingly, lithium-ion batteries modeling, battery heat generation, and thermal management are the main focus of…

Systems and Control · Electrical Eng. & Systems 2024-03-05 Pedram Rabiee , Mohammad Hassan Saidi

A simple nonholonomic dynamics model is developed as a low-order model for generating undulatory swim-like motions, validated through computational fluid dynamics (CFD) simulations. The rigid-body-dynamics model generates swimming motion by…

Fluid Dynamics · Physics 2025-11-27 Jamal Ardister , James Geddes , Brian F. Feeny , Junlin Yuan

For the application of MPC design in on-line regulation or tracking control problems, several studies have attempted to develop an accurate model, and realize adequate uncertainty description of linear or non-linear plants of the processes.…

Optimization and Control · Mathematics 2019-04-03 Yuanqiang Zhou , Dewei Li , Yugeng Xi , Zhongxue Gan

Several methods in nonadiabatic molecular dynamics are based on Madelung's hydrodynamic description of nuclear motion, while the electronic component is treated as a finite-dimensional quantum system. In this context, the quantum potential…

Mathematical Physics · Physics 2024-06-04 François Gay-Balmaz , Cesare Tronci

Besides their huge technological importance, fluidized beds have attracted a large amount of research because they are perfect playgrounds to investigate highly dynamic particulate flows. Their over-all behavior is determined by…

Soft Condensed Matter · Physics 2017-06-20 T. Lichtenegger , S. Pirker

A general phenomenological reaction-diffusion model for flow-induced phase transitions in complex fluids is presented. The model consists of an equation of motion for a nonconserved composition variable, coupled to a Newtonian stress…

Soft Condensed Matter · Physics 2009-11-07 J. L. Goveas , P. D. Olmsted

A new upscaling procedure that provides 1D representations of 2D mixing-limited reactive transport systems is developed and applied. A key complication with upscaled models in this setting is that the procedure must differentiate between…

Fluid Dynamics · Physics 2022-10-05 Ricardo H. Deucher , Louis J. Durlofsky

The aim of this paper is two-fold: (1) to provide a detailed investigation of the turbulent flow in an inline high-shear rotor stator mixer; (2) to provide a comparison of two different classes of turbulence models and solution methods…

Fluid Dynamics · Physics 2023-05-29 Vipin Michael , Umair Ahmed , Mahmoud Assad , Robert Prosser , Adam Kowalski

Multiphase systems are ubiquitous in engineering, biology, and materials science, where understanding their complex interactions and rheological behavior is crucial for advancing applications ranging from emulsion stability to cellular…

Fluid Dynamics · Physics 2025-10-27 Andres Santiago Espinosa-Moreno , Nicolas Moreno , Marco Ellero

Metabolic fluxes are the rates of life-sustaining chemical reactions within a cell and metabolites are the components. Determining the changes in these fluxes is crucial to understanding diseases with metabolic causes and consequences.…

Dynamical Systems · Mathematics 2024-07-15 Breanna Guppy , Colleen Mitchell , Eric Taylor

Thus far, Computational Fluid Dynamics (CFD) simulations fail to predict the electrostatic charging of particle-gas flows reliably. The lack of a predictive tool leads to powder operations prone to deposits and discharges, making chemical…

Fluid Dynamics · Physics 2022-12-12 Holger Grosshans , Simon Jantač

Computer modeling of multicellular systems has been a valuable tool for interpreting and guiding in vitro experiments relevant to embryonic morphogenesis, tumor growth, angiogenesis and, lately, structure formation following the printing of…

Biological Physics · Physics 2015-05-28 Elijah Flenner , Lorant Janosi , Bogdan Barz , Adrian Neagu , Gabor Forgacs , Ioan Kosztin

Energy-based modelling brings engineering insight to the understanding of biomolecular systems. It is shown how well-established control engineering concepts, such as loop-gain, arise from energy feedback loops and are therefore amenable to…

Molecular Networks · Quantitative Biology 2021-03-30 Peter J Gawthrop
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