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In this paper, we introduce the concept of Developmental Partial Differential Equation (DPDE), which consists of a Partial Differential Equation (PDE) on a time-varying manifold with complete coupling between the PDE and the manifold's…

Optimization and Control · Mathematics 2015-09-23 Nastassia Pouradier Duteil , Francesco Rossi , Ugo Boscain , Benedetto Piccoli

We propose the Binary Diffusion Probabilistic Model (BDPM), a generative framework specifically designed for data representations in binary form. Conventional denoising diffusion probabilistic models (DDPMs) assume continuous inputs, use…

Computer Vision and Pattern Recognition · Computer Science 2025-10-01 Vitaliy Kinakh , Slava Voloshynovskiy

This paper investigates how diffusion generative models leverage (unknown) low-dimensional structure to accelerate sampling. Focusing on two mainstream samplers -- the denoising diffusion implicit model (DDIM) and the denoising diffusion…

Machine Learning · Statistics 2025-06-18 Jiadong Liang , Zhihan Huang , Yuxin Chen

We study solution techniques for an evolution equation involving second order derivative in time and the spectral fractional powers, of order $s \in (0,1)$, of symmetric, coercive, linear, elliptic, second-order operators in bounded domains…

Numerical Analysis · Mathematics 2018-06-18 Lehel Banjai , Enrique Otarola

We investigate a simple quantitative genetics model subjet to a gradual environmental change from the viewpoint of the phylogenies of the living individuals. We aim to understand better how the past traits of their ancestors are shaped by…

Probability · Mathematics 2021-04-22 Vincent Calvez , Benoît Henry , Sylvie Méléard , Viet Chi Tran

We consider the evolution of populations under the joint action of mutation and differential reproduction, or selection. The population is modelled as a finite-type Markov branching process in continuous time, and the associated…

Populations and Evolution · Quantitative Biology 2009-02-23 Ellen Baake , Hans-Otto Georgii

This study investigates an SEIS PDE model with a free boundary, which captures the dynamics of epidemic transmission, including diseases like COVID-19. This parabolic PDE system is analyzed in a rotationally symmetric domain, and the…

Analysis of PDEs · Mathematics 2025-11-11 Aesol Jeon , Ki-Ahm Lee

A model of the dynamics of natural rotifer populations is described as a discrete nonlinear map depending on three parameters, which reflect characteristics of the population and environment. Model dynamics and their change by variation of…

Subcellular Processes · Quantitative Biology 2007-05-23 Faina S. Berezovskaya , Georgy P. Karev , Terry W. Snell

We study the evolution of gene frequencies in a population living in $\mathbb{R}^d$, modelled by the spatial Lambda Fleming-Viot process with natural selection (Barton, Etheridge and Veber, 2010 and Etheridge, Veber and Yu, 2014). We…

Probability · Mathematics 2022-10-04 Raphaël Forien , Sarah Penington

We survey continuous-time generative modeling methods based on transporting a simple reference distribution to a data distribution via stochastic or deterministic dynamics. We present a unified framework in which diffusion models,…

Machine Learning · Computer Science 2026-05-11 Aditya Ranganath , Mukesh Singhal

Reaction-diffusion equations describe various spatially extended processes that unfold as traveling fronts moving at constant velocity. We introduce and solve analytically a model that, besides such fronts, supports solutions advancing as…

Biological Physics · Physics 2026-02-13 Louis Brezin , Kyle J. Shaffer , Kirill S. Korolev

We consider the problem of the Bayesian inference of drift and diffusion coefficient functions in a stochastic differential equation given discrete observations of a realisation of its solution. We give conditions for the well-posedness and…

Statistics Theory · Mathematics 2020-04-10 Jean-Charles Croix , Masoumeh Dashti , Istvàn Zoltàn Kiss

Diffusion models, which learn to reverse a signal destruction process to generate new data, typically require the signal at each step to have the same dimension. We argue that, considering the spatial redundancy in image signals, there is…

Machine Learning · Computer Science 2022-11-30 Han Zhang , Ruili Feng , Zhantao Yang , Lianghua Huang , Yu Liu , Yifei Zhang , Yujun Shen , Deli Zhao , Jingren Zhou , Fan Cheng

General self-consistent expressions for the coefficients of diffusion and dynamical friction in a stable, bound, multicomponent self-gravitating and inhomogeneous system are derived. They account for the detailed dynamics of the colliding…

Astrophysics of Galaxies · Physics 2017-06-20 Jean Heyvaerts , Jean-Baptiste Fouvry , Pierre-Henri Chavanis , Christophe Pichon

Radiation therapy outcomes are decided by two key parameters, dose and timing, whose best values vary substantially across patients. This variability is especially critical in the treatment of brain cancer, where fractionated or staged…

Medical Physics · Physics 2025-06-24 Hao Peng , Steve Jiang , Robert Timmerman

Diffusion models have emerged as state-of-the-art generative models for image generation. However, sampling from diffusion models is usually time-consuming due to the inherent autoregressive nature of their sampling process. In this work,…

Machine Learning · Computer Science 2024-05-28 Zhiwei Tang , Jiasheng Tang , Hao Luo , Fan Wang , Tsung-Hui Chang

A fundamental problem in Bayesian inference and statistical machine learning is to efficiently sample from multimodal distributions. Due to metastability, multimodal distributions are difficult to sample using standard Markov chain Monte…

Machine Learning · Statistics 2019-05-27 Yulong Lu , Jianfeng Lu , James Nolen

Diffusion models (DMs) have become the dominant paradigm of generative modeling in a variety of domains by learning stochastic processes from noise to data. Recently, diffusion denoising bridge models (DDBMs), a new formulation of…

Machine Learning · Computer Science 2024-11-01 Guande He , Kaiwen Zheng , Jianfei Chen , Fan Bao , Jun Zhu

We study a reaction-diffusion equation with an integral term describing nonlocal consumption of resources. We show that a homogeneous equilibrium can lose its stability resulting in appearance of stationary spatial structures. It is a new…

Analysis of PDEs · Mathematics 2007-05-23 Stephane Genieys , Vitaly Volpert , Pierre Auger

A birth-death-sampling model gives rise to phylogenetic trees with samples from the past and the present. Interpreting "birth" as branching speciation, "death" as extinction, and "sampling" as fossil preservation and recovery, this model --…

Populations and Evolution · Quantitative Biology 2018-03-12 Tanja Stadler , Alexandra Gavryushkina , Rachel C. M. Warnock , Alexei J. Drummond , Tracy A. Heath