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We focus on the average-case analysis: A function w : V -> Z+ is given which defines the likelihood for a node to be the one marked, and we want the strategy that minimizes the expected number of queries. Prior to this paper, very little…

Data Structures and Algorithms · Computer Science 2009-08-10 Ferdinando Cicalese , Tobias Jacobs , Eduardo Laber , Marco Molinaro

For the tree topology, previous studies show the maximum likelihood estimate (MLE) of a link/path takes a polynomial form with a degree that is one less than the number of descendants connected to the link/path. Since then, the main concern…

Networking and Internet Architecture · Computer Science 2010-04-28 Weiping Zhu

It is a known fact that, given two rooted binary phylogenetic trees, the concept of maximum acyclic agreement forests is sufficient to compute hybridization networks with minimum hybridization number. In this work, we demonstrate by first…

Populations and Evolution · Quantitative Biology 2015-12-18 Benjamin Albrecht

CRISPR technology has enabled large-scale cell lineage tracing for complex multicellular organisms by mutating synthetic genomic barcodes during organismal development. However, these sophisticated biological tools currently use ad-hoc and…

Quantitative Methods · Quantitative Biology 2019-04-02 Jean Feng , William S DeWitt , Aaron McKenna , Noah Simon , Amy Willis , Frederick A Matsen

Reconstructing a parsimonious phylogenetic network that displays multiple phylogenetic trees is an important problem in theory of phylogenetics, where the complexity of the inferred networks is measured by reticulation numbers. The…

Populations and Evolution · Quantitative Biology 2024-08-27 Yufeng Wu , Louxin Zhang

A fundamental problem in the study of phylogenetic networks is to determine whether or not a given phylogenetic network contains a given phylogenetic tree. We develop a quadratic-time algorithm for this problem for binary nearly-stable…

Data Structures and Algorithms · Computer Science 2022-08-29 Philippe Gambette , Andreas D. M. Gunawan , Anthony Labarre , Stéphane Vialette , Louxin Zhang

Maximum likelihood estimation in statistics leads to the problem of maximizing a product of powers of polynomials. We study the algebraic degree of the critical equations of this optimization problem. This degree is related to the number of…

Algebraic Geometry · Mathematics 2007-06-13 Fabrizio Catanese , Serkan Hosten , Amit Khetan , Bernd Sturmfels

In molecular phylogeny, relationships among organisms are reconstructed using DNA or protein sequences and are displayed as trees. A linear increase in the number of sequences results in an exponential increase of possible trees. Thus,…

Genomics · Quantitative Biology 2007-05-23 Kerstin Hoef-Emden

A classical problem in phylogenetic tree analysis is to decide whether there is a phylogenetic tree $T$ that contains all information of a given collection $\cP$ of phylogenetic trees. If the answer is "yes" we say that $\cP$ is compatible…

Combinatorics · Mathematics 2010-06-29 Stefan Grünewald

A tree tensor network variational method is proposed to simulate quantum many-body systems with global symmetries where the optimization is reduced to individual charge configurations. A computational scheme is presented, how to extract the…

Strongly Correlated Electrons · Physics 2013-11-13 Iztok Pizorn , Frank Verstraete , Robert M. Konik

As researchers collect increasingly large molecular data sets to reconstruct the Tree of Life, the heterogeneity of signals in the genomes of diverse organisms poses challenges for traditional phylogenetic analysis. A class of phylogenetic…

Populations and Evolution · Quantitative Biology 2015-09-11 Liang Liu , Zhenxiang Xi , Shaoyuan Wu , Charles Davis , Scott V. Edwards

Most statistical software packages implement numerical strategies for computation of maximum likelihood estimates in random effects models. Little is known, however, about the algebraic complexity of this problem. For the one-way layout…

Statistics Theory · Mathematics 2013-05-07 Elizabeth Gross , Mathias Drton , Sonja Petrović

This paper studies the optimal solution of the classical problem of detecting the location of multiple image occurrences in a two-dimensional, noisy measurement. Assuming the image occurrences do not overlap, we formulate this task as a…

Image and Video Processing · Electrical Eng. & Systems 2024-07-31 Simon Anuk , Tamir Bendory , Amichai Painsky

Quartet trees displayed by larger phylogenetic trees have long been used as inputs for species tree and supertree reconstruction. Computational constraints prevent the use of all displayed quartets in many practical problems due to the…

Populations and Evolution · Quantitative Biology 2016-12-07 Ruth Davidson , MaLyn Lawhorn , Joseph Rusinko , Noah Weber

We apply classical quartet techniques to the problem of phylogenetic decisiveness and find a value $k$ such that all collections of at least $k$ quartets are decisive. Moreover, we prove that this bound is optimal and give a lower-bound on…

Quantitative Methods · Quantitative Biology 2015-03-17 Emili Moan , Joseph Rusinko

Tree Containment is a fundamental problem in phylogenetics useful for verifying a proposed phylogenetic network, representing the evolutionary history of certain species. Tree Containment asks whether the given phylogenetic tree (for…

Populations and Evolution · Quantitative Biology 2024-06-14 Arkadiy Dushatskiy , Esther Julien , Leen Stougie , Leo van Iersel

In this paper, we investigate a conjecture by von Haeseler concerning the Maximum Parsimony method for phylogenetic estimation, which was published by the Newton Institute in Cambridge on a list of open phylogenetic problems in 2007. This…

Populations and Evolution · Quantitative Biology 2010-07-30 Mareike Fischer

A phylogenetic variety is an algebraic variety parameterized by a statistical model of the evolution of biological sequences along a tree. Understanding this variety is an important problem in the area of algebraic statistics with…

Populations and Evolution · Quantitative Biology 2024-05-22 Luis David Garcia Puente , Marina Garrote-López , Elima Shehu

We study QPT (quasi-polynomial tractability) in the worst case setting for linear tensor product problems defined over Hilbert spaces. We assume that the domain space is a reproducing kernel Hilbert space so that function values are well…

Numerical Analysis · Mathematics 2017-08-15 Henryk Woźniakowski , Erich Novak

Decision trees are a popular family of models due to their attractive properties such as interpretability and ability to handle heterogeneous data. Concurrently, missing data is a prevalent occurrence that hinders performance of machine…

Machine Learning · Computer Science 2020-07-01 Pasha Khosravi , Antonio Vergari , YooJung Choi , Yitao Liang , Guy Van den Broeck