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Repeating spatiotemporal spike patterns exist and carry information. Here we investigated how a single spiking neuron can optimally respond to one given pattern (localist coding), or to either one of several patterns (distributed coding,…

Neural and Evolutionary Computing · Computer Science 2018-09-24 Timothée Masquelier , Saeed Reza Kheradpisheh

Traditional neural networks, while powerful, rely on biologically implausible learning mechanisms such as global backpropagation. This paper introduces the Structurally Adaptive Predictive Inference Network (SAPIN), a novel computational…

Neural and Evolutionary Computing · Computer Science 2026-02-11 Brennen A. Hill

Synaptic plasticity poses itself as a powerful method of self-regulated unsupervised learning in neural networks. A recent resurgence of interest has developed in utilizing Artificial Neural Networks (ANNs) together with synaptic plasticity…

Neural and Evolutionary Computing · Computer Science 2021-11-09 Samuel Schmidgall , Joe Hays

The brain anticipates future events using internal models that specify not only what will occur, but also when it will occur and with what probability. We refer to this joint specification of identity, timing, and likelihood as a complete…

Neurons and Cognition · Quantitative Biology 2026-02-27 Yohei Yamada , Zenas C. Chao

Standard Spiking Neural Network (SNN) models typically neglect metabolic constraints, treating neurons as energetically unconstrained components. We bridge this gap by implementing a conductance-based leaky integrate-and-fire (gLIF)…

Neurons and Cognition · Quantitative Biology 2025-12-29 Ece Öner , Cenk Denktaş

This study proposes a novel learning paradigm for spiking neural networks (SNNs) that replaces the perceptron-inspired abstraction with biologically grounded neuron models, jointly optimizing synaptic weights and intrinsic neuronal…

Neural and Evolutionary Computing · Computer Science 2026-03-03 Zofia Rudnicka , Janusz Szczepanski , Agnieszka Pregowska

In this article, we propose a novel Winner-Take-All (WTA) architecture employing neurons with nonlinear dendrites and an online unsupervised structural plasticity rule for training it. Further, to aid hardware implementations, our network…

Neural and Evolutionary Computing · Computer Science 2015-12-07 Subhrajit Roy , Arindam Basu

The brain can learn to execute a wide variety of tasks quickly and efficiently. Nevertheless, most of the mechanisms that enable us to learn are unclear or incredibly complicated. Recently, considerable efforts have been made in…

Neural and Evolutionary Computing · Computer Science 2023-03-28 Mohammad Modiri

Spiking Neural Networks (SNNs) are promising brain-inspired models known for low power consumption and superior potential for temporal processing, but identifying suitable learning mechanisms remains a challenge. Despite the presence of…

Neural and Evolutionary Computing · Computer Science 2025-08-20 Yuzhe Liu , Xin Deng , Qiang Yu

Neurons subject to a common non-stationary input may exhibit a correlated firing behavior. Correlations in the statistics of neural spike trains also arise as the effect of interaction between neurons. Here we show that these two situations…

Quantitative Methods · Quantitative Biology 2021-04-13 Joanna Tyrcha , Yasser Roudi , Matteo Marsili , John Hertz

Spiking neural network is a type of artificial neural network in which neurons communicate between each other with spikes. Spikes are identical Boolean events characterized by the time of their arrival. A spiking neuron has internal…

Neural and Evolutionary Computing · Computer Science 2016-02-16 Oleg Y. Sinyavskiy

We present an effective model for timing-dependent synaptic plasticity (STDP) in terms of two interacting traces, corresponding to the fraction of activated NMDA receptors and the Ca2+ concentration in the dendritic spine of the…

Neurons and Cognition · Quantitative Biology 2015-02-26 Rodrigo Echeveste , Claudius Gros

In neuroscience, learning and memory are usually associated to long-term changes of neuronal connectivity. In this context, synaptic plasticity refers to the set of mechanisms driving the dynamics of neuronal connections, called {\em…

Probability · Mathematics 2021-06-10 Philippe Robert , Gaetan Vignoud

Recent experiments have demonstrated that the timescale of adaptation of single neurons and ion channel populations to stimuli slows down as the length of stimulation increases; in fact, no upper bound on temporal time-scales seems to exist…

Subcellular Processes · Quantitative Biology 2010-04-29 Daniel Soudry , Ron Meir

The modular and hierarchical organization of the brain is believed to support the coexistence of segregated (specialization) and integrated (binding) information processes. A relevant question is yet to understand how such architecture…

Neurons and Cognition · Quantitative Biology 2025-06-19 Raphaël Bergoin , Alessandro Torcini , Gustavo Deco , Mathias Quoy , Gorka Zamora-López

Inspired by the brain, we present a physical alternative to traditional digital neural networks -- a microfluidic network in which nodes are connected by conical, electrolyte-filled channels acting as memristive iontronic synapses. Their…

Soft Condensed Matter · Physics 2025-11-07 Monica Conte , René van Roij , Marjolein Dijkstra

Spiking networks that perform probabilistic inference have been proposed both as models of cortical computation and as candidates for solving problems in machine learning. However, the evidence for spike-based computation being in any way…

Neural and Evolutionary Computing · Computer Science 2017-10-12 Luziwei Leng , Roman Martel , Oliver Breitwieser , Ilja Bytschok , Walter Senn , Johannes Schemmel , Karlheinz Meier , Mihai A. Petrovici

Learning and memory in the brain are implemented by complex, time-varying changes in neural circuitry. The computational rules according to which synaptic weights change over time are the subject of much research, and are not precisely…

Machine Learning · Statistics 2014-11-18 Scott W. Linderman , Christopher H. Stock , Ryan P. Adams

Neurons can display highly variable dynamics. While such variability presumably supports the wide range of behaviors generated by the organism, their gene expressions are relatively stable in the adult brain. This suggests that neuronal…

Neurons and Cognition · Quantitative Biology 2023-11-07 Lu Mi , Trung Le , Tianxing He , Eli Shlizerman , Uygar Sümbül

The synaptic connectivity of cortex is plastic, with experience shaping the ongoing interactions between neurons. Theoretical studies of spike timing-dependent plasticity (STDP) have focused on either just pairs of neurons or large-scale…

Neurons and Cognition · Quantitative Biology 2016-08-02 Gabriel Koch Ocker , Brent Doiron
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