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A single-biomolecule optical toggle-switch is demonstrated based on a mutated green fluorescent protein (GFP). We have exploited molecular biology techniques to tailor GFP molecular structure and photophysical properties and give it…

A structure based on a dimer of silicon nanoparticles, presenting directional scattering in the visible range, was studied as a new design of an all-optical switch. The combination of spherical nanoparticles satisfying, at the same incident…

We discuss implications of a recent experimental breakthrough which uses a fluorescence-doped flexible semiconducting polymer to construct a single-molecule sensor which can detect ultra-weak forces in the molecular environment, with a grey…

Soft Condensed Matter · Physics 2018-02-12 Alessio Zaccone

The prospect of quantum networks, in which quantum information is carried by single photons in photonic circuits, has long been the driving force behind the effort to achieve all-optical routing of single photons. Here we realize the most…

Quantum Physics · Physics 2015-01-08 Itay Shomroni , Serge Rosenblum , Yulia Lovsky , Orel Bechler , Gabriel Guendelman , Barak Dayan

We investigate the possibility of optical current control through single molecules which are weakly coupled to leads. A master equation approach for the transport through a molecule is combined with a Floquet theory for the time-dependent…

Chemical Physics · Physics 2016-09-08 Jörg Lehmann , Sébastien Camalet , Sigmund Kohler , Peter Hänggi

Spatial Fluorescence Cross Correlation Spectroscopy is a rarely investigated version of Fluorescence Correlation Spectroscopy, in which the fluorescence signals from different observation volumes are cross-correlated. In the reported…

Optics · Physics 2008-06-13 Yoann Blancquaert , Jie Gao , Jacques Derouard , Antoine Delon

While experiments with one or two quantum emitters have become routine in various laboratories, scalable platforms for efficient optical coupling of many quantum systems remain elusive. To address this issue, we report on chip-based systems…

Two-dimensional electronic spectroscopy provides information on coupling and energy transfer between excited states on ultrafast timescales. Only recently, incoherent fluorescence detection has made it possible to combine this method with…

Optics · Physics 2025-05-14 Sanchayeeta Jana , Simon Durst , Lucas Ludwig , Markus Lippitz

We employ heterodyne interferometry to investigate the effect of a single organic molecule on the phase of a propagating laser beam. We report on the first phase-contrast images of individual molecules and demonstrate a single-molecule…

Quantum Physics · Physics 2015-05-27 M. Pototschnig , Y. Chassagneux , J. Hwang , G. Zumofen , A. Renn , V. Sandoghdar

We present a scheme to realize two-direction optical switch by a single-mode optical cavity containing some four-level atoms. The high switching efficiency can be obtained through low photon loss and large third-order nonlinear…

Optics · Physics 2018-07-04 Miaodi Guo , Xuemei Su

All-optical, mirrorless switching and bistability is demonstrated with bacteriorhodopsin (bR). A low-power, 532 nm laser beam modulates the transmission of a cw laser beam at 635 nm that corresponds to peak absorption of the O-excited state…

Optics · Physics 2009-11-10 S. Roy , P. Sharma , A. K. Dharmadhikari , D. Mathur

The pioneering experiments of linear spectroscopy were performed using flames in the 1800s, but nonlinear optical measurements had to wait until lasers became available in the twentieth century. Because the nonlinear cross section of…

Quantum Physics · Physics 2016-07-13 Andreas Maser , Benjamin Gmeiner , Tobias Utikal , Stephan Götzinger , Vahid Sandoghdar

Switching anisotropic molecules from strongly-absorbing to strongly-amplifying through a transparent state is shown to be possible by application of dc or ac control electric fields without the requirement of the population inversion. It is…

Quantum Physics · Physics 2015-06-26 A. K. Popov , V. V. Slabko

We apply a first-principles computational approach to study a light-sensitive molecular switch. The molecule that comprises the switch can convert between a trans and a cis configuration upon photo-excitation. We find that the conductance…

Mesoscale and Nanoscale Physics · Physics 2015-06-18 Chun Zhang , M. -H. Du , H. -P. Cheng , X. -G. Zhang , A. E. Roitberg , J. L. Krause

All-optical switches are introduced which are based on deoxyribonucleic acid (DNA) in the form of electrospun fibers, where DNA is semi-intercalated with a push-pull, luminescent nonlinear pyrazoline derivative. Optical birefringence is…

Applied Physics · Physics 2018-12-18 Adam Szukalski , Maria Moffa , Andrea Camposeo , Dario Pisignano , Jaroslaw Mysliwiec

The advent of single molecule optics has had a profound impact in fields ranging from biophysics to material science, photophysics, and quantum optics. However, all existing room-temperature single molecule methods have been based on…

Mesoscale and Nanoscale Physics · Physics 2010-07-22 Michele Celebrano , Philipp Kukura , Alois Renn , Vahid Sandoghdar

Azophenine has previously been identified as a controllable molecular switch when deposited on a Cu(110) surface, where it can be in two symmetry-equivalent states. Each of the two states can be set as well as read by means of a scanning…

Atomic and Molecular Clusters · Physics 2018-01-04 Herbert Fruchtl , Tanja van Mourik

We demonstrate a fiber-optical switch that is activated at tiny energies corresponding to few hundred optical photons per pulse. This is achieved by simultaneously confining both photons and a small laser-cooled ensemble of atoms inside the…

Quantum Physics · Physics 2015-05-13 M. Bajcsy , S. Hofferberth , V. Balic , T. Peyronel , M. Hafezi , A. S. Zibrov , V. Vuletic , M. D. Lukin

We discuss the influence of the superconducting transition in a film on the fluorescence spectrum of a single molecule located nearby. We show that single molecule spectroscopy (SMS) should be an appropriate tool to detect the electric…

Superconductivity · Physics 2007-05-23 M. Faure , B. Lounis , A. I. Buzdin

Single molecule FRET (fluorescence resonance energy transfer) is a powerful technique for detecting real-time conformational changes and molecular interactions during biological reactions. In this review, we examine different techniques of…

Biomolecules · Quantitative Biology 2007-05-23 Ivan Rasnik , Sean A. McKinney , Taekjip Ha
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