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Recent methodological advances are enabling better examination of speciation and extinction processes and patterns. A major open question is the origin of large discrepancies in species number between groups of the same age. Existing…

Populations and Evolution · Quantitative Biology 2015-09-01 Sacha Laurent , Marc Robinson-Rechavi , Nicolas Salamin

The margins within the geographic range of species are often specific in terms of ecological and evolutionary processes, and can strongly influence the species' reaction to climate change. One of the frequently observed features at range…

Populations and Evolution · Quantitative Biology 2020-02-28 R. Juhász , B. Oborny

By creating networks of biochemical pathways, communities of micro-organisms are able to modulate the properties of their environment and even the metabolic processes within their hosts. Next-generation high-throughput sequencing has led to…

Applications · Statistics 2023-03-28 Molly G. Hayes , Morgan G. I. Langille , Hong Gu

We have used the Monte Carlo based computer models to show that selection pressure could affect the distribution of recombination hotspots along the chromosome. Close to critical crossover rate, where genomes may switch between the…

Genomics · Quantitative Biology 2015-05-13 Jakub Kowalski , Wojciech Waga , Marta Zawierta , Stanislaw Cebrat

Proliferation and motility are ubiquitous drivers of activity in biological systems. Here, we study a dense binary mixture of motile and proliferating particles with exclusively repulsive interactions, where homeostasis in the proliferating…

Soft Condensed Matter · Physics 2025-06-11 Lukas Hupe , Joanna M. Materska , David Zwicker , Ramin Golestanian , Bartlomiej Waclaw , Philip Bittihn

When a biological population expands into new territory, genetic drift develops an enormous influence on evolution at the propagating front. In such range expansion processes, fluctuations in allele frequencies occur through stochastic…

Biological Physics · Physics 2018-12-24 Sherry Chu , Mehran Kardar , David R. Nelson , Daniel A. Beller

Communication and coordination play a major role in the ability of bacterial cells to adapt to ever changing environments and conditions. Recent work has shown that such coordination underlies several aspects of bacterial responses…

Quantitative Methods · Quantitative Biology 2016-04-12 Shashank Singh , Sabrina Rashid , Zhicheng Long , Saket Navlakha , Hanna Salman , Zoltan N. Oltvai , Ziv Bar-Joseph

We prove a global existence result for a model describing the swarming phenomenon of the bacterium Proteus mirabilis. The model consists of an ordinary differential equation coupled with an age-structured equation involving nonlinear…

Analysis of PDEs · Mathematics 2008-09-09 Philippe Laurençot , Christoph Walker

In a recent work [arXiv:1307.1382] it was pointed out that the link-weight distribution of microRNA (miRNA) co-target network of a wide class of species are universal up to scaling. The number cell types, widely accepted as a measure of…

Genomics · Quantitative Biology 2014-05-20 Mahashweta Basu , Nitai P. Bhattacharyya , P. K. Mohanty

We investigate the nature of genetic drift acting at the leading edge of range expansions, building on recent results in [Hallatschek et al., Proc.\ Natl.\ Acad.\ Sci., \textbf{104}(50): 19926 - 19930 (2007)]. A well mixed population of two…

Populations and Evolution · Quantitative Biology 2010-08-16 Adnan Ali , Stefan Grosskinsky

Recent microbial experiments suggest that enhanced genetic drift at the frontier of a two-dimensional range expansion can cause genetic sectoring patterns with fractal domain boundaries. Here, we propose and analyze a simple model of…

Populations and Evolution · Quantitative Biology 2008-12-12 Oskar Hallatschek , David R. Nelson

Until recently, much of the microbial world was hidden from view. A global research effort has changed this, unveiling and quantifying microbial diversity across enormous range of critically-important contexts, from the human microbiome, to…

Populations and Evolution · Quantitative Biology 2017-10-26 Alice Doucet-Beaupré , James P. O'Dwyer

We study the diffusion front for a natural two-dimensional model where many particles starting at the origin diffuse independently. It turns out that this model can be described using properties of near-critical percolation, and provides a…

Probability · Mathematics 2009-12-21 Pierre Nolin

With the development of high throughput sequencing technology, it becomes possible to directly analyze mutation distribution in a genome-wide fashion, dissociating mutation rate measurements from the traditional underlying assumptions.…

Genomics · Quantitative Biology 2015-05-14 D. Parkhomchuk , V. S. Amstislavskiy , A. Soldatov , V. Ogryzko

Morphogenetic patterns are highly sophisticated dissipative structures. Are they governed by the same general mechanisms as chemical and hydrodynamic patterns? Turing's symmetry breaking and Wolpert's signalling provide alternative…

Pattern Formation and Solitons · Physics 2019-05-22 L. M. Pismen

Bacteria and their bacteriophages are the most abundant, widespread and diverse groups of biological entities on the planet. In an attempt to understand how the interactions between bacteria, virulent phages and temperate phages might…

Populations and Evolution · Quantitative Biology 2009-11-13 Martin Rosvall , Ian B. Dodd , Sandeep Krishna , Kim Sneppen

Bacterial genomes and large-scale computer software projects both consist of a large number of components (genes or software packages) connected via a network of mutual dependencies. Components can be easily added or removed from individual…

Molecular Networks · Quantitative Biology 2013-08-12 Tin Yau Pang , Sergei Maslov

Mixing fronts form when fluids with different chemical compositions are brought into contact. They influence a large range of biogeochemical processes in hydrological systems. An important mechanism governing mixing rates in such fronts is…

Fluid Dynamics · Physics 2023-09-13 Gauthier Rousseau , Satoshi Izumoto , Tanguy Le Borgne , Joris Heyman

Spreading of bacteria in a highly advective, disordered environment is examined. Predictions of super-diffusive spreading for a simplified reaction-diffusion equation are tested. Concentration profiles display anomalous growth and…

Biological Physics · Physics 2007-05-23 John H. Carpenter , Karin A. Dahmen

Textual analysis of typical microbial genomes reveals that they have the statistical characteristics of a DNA sequence of a much shorter length. This peculiar property supports an evolutionary model in which a genome evolves by random…

Biological Physics · Physics 2009-11-07 L. C. Hsieh , L. F. Luo , F. M. Ji , H. C. Lee