Related papers: Spike timing precision and neural error correction…

Background: In neurophysiological data, latency refers to a global shift of spikes from one spike train to the next, either caused by response onset fluctuations or by finite propagation speed. Such systematic shifts in spike timing lead to…

We derive a synaptic weight update rule for learning temporally precise spike train to spike train transformations in multilayer feedforward networks of spiking neurons. The framework, aimed at seamlessly generalizing error backpropagation…

A single neuron is known to generate almost identical spike trains when the same fluctuating input is repeatedly applied. Here, we study the reliability of spike firing in a pulse-coupled network of oscillator neurons receiving fluctuating…

Using a realistic model of activity dependent dynamical synapses and a standard integrate and fire neuron model we study, both analytically and numerically, the conditions in which a postsynaptic neuron efficiently detects temporal…

Although recent neurophysiological experiments suggest that synchronous neural activity is involved in some perceptual and cognitive processes, the functional role of such coherent neuronal behavior is not well understood. As a first step…

In timing-based neural codes, neurons have to emit action potentials at precise moments in time. We use a supervised learning paradigm to derive a synaptic update rule that optimizes via gradient ascent the likelihood of postsynaptic firing…

Synapses change on multiple timescales, ranging from milliseconds to minutes, due to a combination of both short- and long-term plasticity. Here we develop an extension of the common Generalized Linear Model to infer both short- and…

This paper uses a simple optogenetic model to compare the timing distortion between a randomly-generated target spike sequence and an externally-stimulated neuron spike sequence. Optogenetics is an emerging field of neuroscience where…

In the last century, most sensorimotor studies of cortical neurons relied on average firing rates. Rate coding is efficient for fast sensorimotor processing that occurs within a few seconds. Much less is known about the neural mechanisms…

Neural variability plays a central role in neural coding and neuronal network dynamics. Unreliability of synaptic transmission is a major source of neural variability: synaptic neurotransmitter vesicles are released probabilistically in…

We study a network model of two conductance-based pacemaker neurons of differing natural frequency, coupled with either mutual excitation or inhibition, and receiving shared random inhibitory synaptic input. The networks may phase-lock…

Why do neurons communicate through spikes? By definition, spikes are all-or-none neural events which occur at continuous times. In other words, spikes are on one side binary, existing or not without further details, and on the other can…

While spike timing has been shown to carry detailed stimulus information at the sensory periphery, its possible role in network computation is less clear. Most models of computation by neural networks are based on population firing rates.…

Spike time response curves (STRC's) are used to study the influence of synaptic stimuli on the firing times of a neuron oscillator without the assumption of weak coupling. They allow us to approximate the dynamics of synchronous state in…

We experimentally show that the neuron functions as a precise time-integrator, where the accumulated changes in neuronal response latencies, under complex and random stimulation patterns, are solely a function of a global quantity, the…

Precise timing of spikes and temporal locking are key elements of neural computation. Here we demonstrate how even strongly heterogeneous, deterministic neural networks with delayed interactions and complex topology can exhibit periodic…

Spiking neuronal networks are usually simulated with three main simulation schemes: the classical time-driven and event-driven schemes, and the more recent hybrid scheme. All three schemes evolve the state of a neuron through a series of…

Predictive coding can be regarded as a function which reduces the error between an input signal and a top-down prediction. If reducing the error is equivalent to reducing the influence of stimuli from the environment, predictive coding can…

We address the problem of identifying functional interactions among stochastic neurons with variable-length memory from their spiking activity. The neuronal network is modeled by a stochastic system of interacting point processes with…

Spike generation in neurons produces a temporal point process, whose statistics is governed by intrinsic phenomena and the external incoming inputs to be coded. In particular, spike-evoked adaptation currents support a slow temporal process…