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Sequence alignment is common nowadays as it is used in many fields to determine how closely two sequences are related and at times to see how little they differ. In computational biology / Bioinformatics, there are many algorithms developed…

Information Theory · Computer Science 2023-05-02 Bharath Reddy , Richard Fields

Functions of chemical composition are complex and discrete in nature making it impossible to optimize them with gradient methods. Genetic algorithms, which do not use derivative information, are used to maximize the thermal conductivity of…

Materials Science · Physics 2018-01-30 Alexander Kerr , Kieran Mullen

The alignment of biological sequences such as DNA, RNA, and proteins, is one of the basic tools that allow to detect evolutionary patterns, as well as functional/structural characterizations between homologous sequences in different…

Quantitative Methods · Quantitative Biology 2023-05-01 Louise Budzynski , Andrea Pagnani

In this paper we present a new algorithm for a layout optimization problem: this concerns the placement of weighted polygons inside a circular container, the two objectives being to minimize imbalance of mass and to minimize the radius of…

Computational Geometry · Computer Science 2008-09-30 Yi-Chun Xu , Ren-Bin Xiao , Martyn Amos

In this paper, we present novel randomized algorithms for solving saddle point problems whose dual feasible region is given by the direct product of many convex sets. Our algorithms can achieve an ${\cal O}(1/N)$ and ${\cal O}(1/N^2)$ rate…

Optimization and Control · Mathematics 2015-11-16 Cong Dang , Guanghui Lan

This study combines simulated annealing with delta evaluation to solve the joint stratification and sample allocation problem. In this problem, atomic strata are partitioned into mutually exclusive and collectively exhaustive strata. Each…

Artificial Intelligence · Computer Science 2021-11-23 Mervyn O'Luing , Steven Prestwich , S. Armagan Tarim

Several recently proposed semi--automatic and fully--automatic coarse--graining schemes for polymer simulations are discussed. All these techniques derive effective potentials for multi--atom units or super--atoms from atomistic…

Soft Condensed Matter · Physics 2007-05-23 Roland Faller

We introduce a method for manifold alignment of different modalities (or domains) of remote sensing images. The problem is recurrent when a set of multitemporal, multisource, multisensor and multiangular images is available. In these…

Computer Vision and Pattern Recognition · Computer Science 2021-04-19 Devis Tuia , Michele Volpi , Maxime Trolliet , Gustau Camps-Valls

Biological network alignment is currently in a state of disarray, with more than two dozen network alignment tools having been introduced in the past decade, with no clear winner, and other new tools being published almost quarterly. Part…

Molecular Networks · Quantitative Biology 2017-09-06 Dillon P. Kanne , Wayne B. Hayes

This paper addresses the path selection problem from a known sender to the receiver. The proposed work shows path selection using genetic algorithm(GA)and simulated annealing (SA) approaches. In genetic algorithm approach, the multi point…

Neural and Evolutionary Computing · Computer Science 2016-09-08 T. R. Gopalakrishnan Nair , Kavitha Sooda

We study the problem of image alignment for panoramic stitching. Unlike most existing approaches that are feature-based, our algorithm works on pixels directly, and accounts for errors across the whole images globally. Technically, we…

Computer Vision and Pattern Recognition · Computer Science 2019-09-04 Yuelong Li , Mohammad Tofighi , Vishal Monga

This paper considers convex optimization problems where nodes of a network have access to summands of a global objective. Each of these local objectives is further assumed to be an average of a finite set of functions. The motivation for…

Optimization and Control · Mathematics 2015-06-16 Aryan Mokhtari , Alejandro Ribeiro

In this paper, we propose a novel Dual Inexact Splitting Algorithm (DISA) for distributed convex composite optimization problems, where the local loss function consists of a smooth term and a possibly nonsmooth term composed with a linear…

Optimization and Control · Mathematics 2023-04-25 Luyao Guo , Xinli Shi , Shaofu Yang , Jinde Cao

The progressive hedging algorithm (PHA) is a cornerstone among algorithms for large-scale stochastic programming problems. However, its traditional implementation is hindered by some limitations, including the requirement to solve all…

Optimization and Control · Mathematics 2025-03-13 Di Zhang , Yihang Zhang , Suvrajeet Sen

Pyrosequencing is among the emerging sequencing techniques, capable of generating upto 100,000 overlapping reads in a single run. This technique is much faster and cheaper than the existing state of the art sequencing technique such as…

Genomics · Quantitative Biology 2016-09-08 Fahad Saeed , Ashfaq Khokhar , Osvaldo Zagordi , Niko Beerenwinkel

Binary segmentation, which is sequential in nature is thus far the most widely used method for identifying multiple change points in statistical models. Here we propose a top down methodology called arbitrary segmentation that proceeds in a…

Statistics Theory · Mathematics 2019-06-12 Abhishek Kaul , Venkata K Jandhyala , Stergios B Fotopoulos

The quadratic assignment problem (QAP) is one of the most difficult combinatorial optimization problems. One of the most powerful and commonly used heuristics to obtain approximations to the optimal solution of the QAP is simulated…

Neural and Evolutionary Computing · Computer Science 2011-11-08 Gerald Paul

Although with progress in introducing auxiliary amortized inference models, learning discrete latent variable models is still challenging. In this paper, we show that the annoying difficulty of obtaining reliable stochastic gradients for…

Machine Learning · Statistics 2020-05-29 Zhijian Ou , Yunfu Song

We consider the variable selection problem of generalized linear models (GLMs). Stability selection (SS) is a promising method proposed for solving this problem. Although SS provides practical variable selection criteria, it is…

Machine Learning · Statistics 2025-08-06 Takashi Takahashi , Yoshiyuki Kabashima

We suggest a new multi-modal algorithm for joint inference of paired structurally aligned samples with Rectified Flow models. While some existing methods propose a codependent generation process, they do not view the problem of joint…

Computer Vision and Pattern Recognition · Computer Science 2026-04-24 Boyi Pang , Savva Ignatyev , Vladimir Ippolitov , Ramil Khafizov , Yurii Melnik , Oleg Voynov , Maksim Nakhodnov , Aibek Alanov , Xiaopeng Fan , Peter Wonka , Evgeny Burnaev