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We construct toric codes on various high-dimensional manifolds. Assuming a conjecture in geometry we find families of quantum CSS stabilizer codes on $N$ qubits with logarithmic weight stabilizers and distance $N^{1-\epsilon}$ for any…

Quantum Physics · Physics 2016-08-19 M. B. Hastings

The sequence-dependent elasticity of double-helical DNA on a nm length scale can be captured by the rigid base-pair model, whose strains are the relative position and orientation of adjacent base-pairs. Corresponding elastic potentials have…

Biomolecules · Quantitative Biology 2013-05-29 Nils B. Becker , Ralf Everaers

A three-dimensional model of the genetic vocabulary is proposed in terms of determinative degree, an introduced characteristic of nucleotide, which reflects absolute difference between purin and pyrimidin bases in one DNA strand. In the…

Chemical Physics · Physics 2007-05-23 Diana Duplij , Steven Duplij

We study the dynamics of a lattice hard-core boson gas released from a domain wall initial state in the presence of two weak links (defects). When the two defects are separated by a finite distance, the resulting density profile exhibits…

Quantum Gases · Physics 2026-04-01 A. Takacs , J. Dubail , P. Calabrese

In the human genomes, recombination frequency between homologous chromosomes during meiosis is highly correlated with their physical length while it differs significantly when their coding density is considered. Furthermore, it has been…

Populations and Evolution · Quantitative Biology 2010-02-01 Dorota Mackiewicz , Marta Zawierta , Wojciech Waga , Stanislaw Cebrat

Protein structures can be encoded into binary sequences, these are used to define a Hamming distance in conformational space: the distance between two different molecular conformations is the number of different bits in their sequences.…

Biological Physics · Physics 2008-12-14 Cyril Laboulais , Mohammed Ouali , Marc Le Bret , Jacques Gabarro-Arpa

Parts of DNA sequences known as exons and introns play very different role in coding and storage of genetic information. Here we show that their conducting properties are also very different. Taking into account long-range correlations…

Soft Condensed Matter · Physics 2015-05-14 A. A. Krokhin , V. M. K. Bagci , F. M. Izrailev , O. V. Usatenko , V. A. Yampol'skii

The quantum enveloping algebra U_q(sl(2) \oplus sl(2)) in the limit q \to 0 is proposed as a symmetry algebra for the genetic code. In this approach the triplets of nucleotids or codons in the DNA chain are classified in crystal bases,…

Biological Physics · Physics 2009-10-31 L. Frappat , A. Sciarrino , P. Sorba

Heaps' or Herdan's law is a linguistic law describing the relationship between the vocabulary/dictionary size (type) and word counts (token) to be a power-law function. Its existence in genomes with certain definition of DNA words is…

Genomics · Quantitative Biology 2024-07-02 Wentian Li , Yannis Almirantis , Astero Provata

We recently introduced a physical model [Hoang et al., P. Natl. Acad. Sci. USA (2004), Banavar et al., Phys. Rev. E (2004)] for proteins which incorporates, in an approximate manner, several key features such as the inherent anisotropy of a…

Biomolecules · Quantitative Biology 2007-05-23 Trinh X. Hoang , Antonio Trovato , Flavio Seno , Jayanth R. Banavar , Amos Maritan

In special coordinates (codon position--specific nucleotide frequencies) bacterial genomes form two straight lines in 9-dimensional space: one line for eubacterial genomes, another for archaeal genomes. All the 348 distinct bacterial…

Genomics · Quantitative Biology 2007-11-13 A. N. Gorban , A. Yu. Zinovyev

Given a set of sequences, the distance between pairs of them helps us to find their similarity and derive structural relationship amongst them. For genomic sequences such measures make it possible to construct the evolution tree of…

Information Theory · Computer Science 2012-08-29 Sandeep Hosangadi

The genetic code underlying protein synthesis is a canonical example of a degenerate biological system. Degeneracies in physical and biological systems can be lifted by external perturbations thus allowing degenerate systems to exhibit a…

Genomics · Quantitative Biology 2013-04-23 Arvind R. Subramaniam , Tao Pan , Philippe Cluzel

In DNA-based data storage, DNA codes with biochemical constraints and error correction are designed to protect data reliability. Single-stranded DNA sequences with secondary structure avoidance (SSA) help to avoid undesirable secondary…

Information Theory · Computer Science 2023-07-04 Shu Liu , Chaoping Xing , Yaqian Zhang

We perform an exhaustive analysis of genome statistics for organisms, particularly extremophiles, growing in a wide range of physicochemical conditions. Specifically, we demonstrate how the correlation between the frequency of amino acids…

Genomics · Quantitative Biology 2013-09-19 Benjamin Greenbaum , Pradeep Kumar , Albert Libchaber

We study the thermodynamic behavior of a model protein with 54 amino acids that is designed to form a three-helix bundle in its native state. The model contains three types of amino acids and five to six atoms per amino acid, and has the…

Soft Condensed Matter · Physics 2007-05-23 Anders Irbäck , Fredrik Sjunnesson , Stefan Wallin

There is an intrinsic relationship between the molecular evolution in primordial period and the properties of genomes and proteomes of contemporary species. The genomic data may help us understand the driving force of evolution of life at…

Genomics · Quantitative Biology 2009-11-25 Dirson Jian Li , Shengli Zhang

The biggest challenge when using DNA as a storage medium is maintaining its stability. The relative occurrence of Guanine (G) and Cytosine (C) is essential for the longevity of DNA. In addition to that, reverse complementary base pairs…

Information Theory · Computer Science 2023-08-03 NallappaBhavithran G , Selvakumar R

A model for the information transfer from DNA to protein using quantum information and computation techniques is presented. DNA is modeled as the sender and proteins are modeled as the receiver of this information. On the DNA side, a…

Quantum Physics · Physics 2008-01-21 Ioannis G. Karafyllidis

This note represents the further progress in understanding the determination of the genetic code by Golden mean (Rakocevic, 1998). Three classes of amino acids that follow from this determination (the 7 "golden" amino acids, 7 of their…

Biomolecules · Quantitative Biology 2009-03-25 Miloje M. Rakocevic
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