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Amino acid sequence portrays most intrinsic form of a protein and expresses primary structure of protein. The order of amino acids in a sequence enables a protein to acquire a particular stable conformation that is responsible for the…

Machine Learning · Computer Science 2022-08-29 Ashish Ranjan , Md Shah Fahad , David Fernandez-Baca , Akshay Deepak , Sudhakar Tripathi

Sequence-to-sequence constituent parsing requires a linearization to represent trees as sequences. Top-down tree linearizations, which can be based on brackets or shift-reduce actions, have achieved the best accuracy to date. In this paper,…

Computation and Language · Computer Science 2020-05-28 Daniel Fernández-González , Carlos Gómez-Rodríguez

We introduce a novel ensemble approach for feature selection based on hierarchical stacking for non-stationarity and/or a limited number of samples with a large number of features. Our approach exploits the co-dependency between features…

Machine Learning · Computer Science 2024-10-08 Aysin Tumay , Mustafa E. Aydin , Ali T. Koc , Suleyman S. Kozat

Biological sequence comparison is a key step in inferring the relatedness of various organisms and the functional similarity of their components. Thanks to the Next Generation Sequencing efforts, an abundance of sequence data is now…

Machine Learning · Computer Science 2016-09-13 Dhananjay Kimothi , Akshay Soni , Pravesh Biyani , James M. Hogan

An important problem in multi-label classification is to capture label patterns or underlying structures that have an impact on such patterns. This paper addresses one such problem, namely how to exploit hierarchical structures over labels.…

Machine Learning · Computer Science 2015-04-17 Jinseok Nam , Johannes Fürnkranz

Multi-label classification is an important yet challenging task in natural language processing. It is more complex than single-label classification in that the labels tend to be correlated. Existing methods tend to ignore the correlations…

Computation and Language · Computer Science 2018-06-18 Pengcheng Yang , Xu Sun , Wei Li , Shuming Ma , Wei Wu , Houfeng Wang

In this paper we present a novel Neural Network algorithm for conducting semi-supervised learning for sequence labeling tasks arranged in a linguistically motivated hierarchy. This relationship is exploited to regularise the representations…

Computation and Language · Computer Science 2016-12-30 Jonathan Godwin , Pontus Stenetorp , Sebastian Riedel

Alignment algorithms usually rely on simplified models of gaps for computational efficiency. Based on an isomorphism between alignments and physical helix-coil models, we show in statistical mechanics that alignments with realistic laws for…

Genomics · Quantitative Biology 2015-06-26 E. Yeramian , E. Debonneuil

Entity alignment is to find identical entities in different knowledge graphs. Although embedding-based entity alignment has recently achieved remarkable progress, training data insufficiency remains a critical challenge. Conventional…

Artificial Intelligence · Computer Science 2022-03-15 Kexuan Xin , Zequn Sun , Wen Hua , Bing Liu , Wei Hu , Jianfeng Qu , Xiaofang Zhou

In this paper, we develop a neural summarization model which can effectively process multiple input documents and distill Transformer architecture with the ability to encode documents in a hierarchical manner. We represent cross-document…

Computation and Language · Computer Science 2019-05-31 Yang Liu , Mirella Lapata

Robust language processing systems are becoming increasingly important given the recent awareness of dangerous situations where brittle machine learning models can be easily broken with the presence of noises. In this paper, we introduce a…

Computation and Language · Computer Science 2019-11-25 Zhiwei Wang , Hui Liu , Jiliang Tang , Songfan Yang , Gale Yan Huang , Zitao Liu

Motivation: The multiple sequence alignment (MSA) problem has been extensively studied, with numerous approaches developed over recent years. With the rapid growth of sequence data, there is an increasing need for fast and accurate MSA…

Computational Engineering, Finance, and Science · Computer Science 2026-01-23 Emily G. Light , Morgan Prior , Noah M. Daniels , Najib Ishaq

Inferring the structural properties of a protein from its amino acid sequence is a challenging yet important problem in biology. Structures are not known for the vast majority of protein sequences, but structure is critical for…

Machine Learning · Computer Science 2019-10-17 Tristan Bepler , Bonnie Berger

We present algorithms for aligning components of Abstract Meaning Representation (AMR) graphs to spans in English sentences. We leverage unsupervised learning in combination with heuristics, taking the best of both worlds from previous AMR…

Computation and Language · Computer Science 2021-06-14 Austin Blodgett , Nathan Schneider

A heuristic extending the Squarified Treemap technique for the representation of hierarchical information as treemaps is presented. The original technique gives high quality treemap views, since items are laid out with rectangles that…

Human-Computer Interaction · Computer Science 2016-09-06 Antonio Cesarano , FIlomena Ferrucci , Mario Torre

A scalable graphical method is presented for selecting, and partitioning datasets for the training phase of a classification task. For the heuristic, a clustering algorithm is required to get its computation cost in a reasonable proportion…

Machine Learning · Computer Science 2019-07-25 Sumedh Yadav , Mathis Bode

The alignment of biological sequences such as DNA, RNA, and proteins, is one of the basic tools that allow to detect evolutionary patterns, as well as functional/structural characterizations between homologous sequences in different…

Quantitative Methods · Quantitative Biology 2023-05-01 Louise Budzynski , Andrea Pagnani

We introduce a multiple testing procedure (TreeBH) which addresses the challenge of controlling error rates at multiple levels of resolution. Conceptually, we frame this problem as the selection of hypotheses which are organized…

Methodology · Statistics 2018-10-25 Marina Bogomolov , Christine B. Peterson , Yoav Benjamini , Chiara Sabatti

We present an extension of Felsenstein's algorithm to indel models defined on entire sequences, without the need to condition on one multiple alignment. The algorithm makes use of a generalization from probabilistic substitution matrices to…

Populations and Evolution · Quantitative Biology 2014-10-24 Oscar Westesson , Gerton Lunter , Benedict Paten , Ian Holmes

Time series imputation benefits from leveraging cross-feature correlations, yet existing attention-based methods re-discover feature relationships at each layer, lacking persistent anchors to maintain consistent representations. To address…

Machine Learning · Computer Science 2026-05-05 Fengming Zhang , Wenjie Du , Huan Zhang , Ke Yu , Shen Qu