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Using basic properties of p-adic numbers, we consider a simple new approach to describe main aspects of DNA sequence and genetic code. Central role in our investigation plays an ultrametric p-adic information space which basic elements are…

Genomics · Quantitative Biology 2010-12-01 Branko Dragovich , Alexandra Dragovich

This paper gives an expository account of our experiments concerning relations between modular forms for congruence subgroups of SL(3,Z) and three dimensional Galois representations. The main new result presented here is a calculation of…

Number Theory · Mathematics 2008-02-03 Bert van Geemen , Jaap Top

Many modified genetic codes are found in specific genomes in which one or more codons have been reassigned to a different amino acid from that in the canonical code. We present a model that unifies four possible mechanisms for reassignment,…

Populations and Evolution · Quantitative Biology 2007-07-17 Supratim Sengupta , Paul G. Higgs

Evolving genomes increase a number of their genes by gene duplications. To escape degradation in a functionless pseudogene, any gene duplicate needs to be guarded by negative (purifying) selection from otherwise inevitable fixation of…

Populations and Evolution · Quantitative Biology 2007-05-23 Dmitri Parkhomchuk , Sergei Rodin

Convolutional codes are error-correcting linear codes that utilize shift registers to encode. These codes have an arbitrary block size and they can incorporate both past and current information bits. DNA codes represent DNA sequences and…

Information Theory · Computer Science 2021-11-09 Paridhi Latawa , Nuh Aydin

Background: There is a 3-fold redundancy in the Genetic Code; most amino acids are encoded by more than one codon. These synonymous codons are not used equally; there is a Codon Usage Bias (CUB). This article will provide novel information…

Biomolecules · Quantitative Biology 2008-07-25 Jan C Biro

One of the main problems of subspace coding asks for the maximum possible cardinality of a subspace code with minimum distance at least $d$ over $\mathbb{F}_q^n$, where the dimensions of the codewords, which are vector spaces, are contained…

Combinatorics · Mathematics 2019-12-24 Daniel Heinlein , Michael Kiermaier , Sascha Kurz , Alfred Wassermann

A superspace model of knots and links for DNA time series data is proposed to take into account the feedback loop from docking to undocking state of protein-protein interactions. In particular, the direction of interactions between the 8…

General Physics · Physics 2018-05-01 Salvatore Capozziello , Richard Pincak

In evolutionary policy search, neural networks are usually represented using a direct mapping: each gene encodes one network weight. Indirect encoding methods, where each gene can encode for multiple weights, shorten the genome to reduce…

Neural and Evolutionary Computing · Computer Science 2024-12-13 Tarek Kunze , Paul Templier , Dennis G Wilson

$\textbf{Background:}$ High mutability of HIV is the driving force of antiretroviral drug resistance, which represents a medical care challenge. $\textbf{Method and Model Equation:}$ To detect the mutability of each gene in the HIV-1…

Other Quantitative Biology · Quantitative Biology 2019-11-11 Eslam Abbas

Genomes evolve as modules. In prokaryotes (and some eukaryotes), genetic material can be transferred between species and integrated into the genome via homologous or illegitimate recombination. There is little reason to imagine that the…

Genomics · Quantitative Biology 2008-01-29 Cheong Xin Chan , Robert G. Beiko , Aaron E. Darling , Mark A. Ragan

We have presented the basic knowledge on the structure of molecules coding the genetic information, mechanisms of transfer of this information from DNA to proteins and phenomena connected with replication of DNA. In particular, we have…

Genomics · Quantitative Biology 2009-09-30 Dorota Mackiewicz , Stanislaw Cebrat

Important aspects of the process of information storage and retrieval in DNA and RNA, and its evolution, are the role of the anticodons and associated $t$RNA's, and correlations between anticodons and amino acids; the degeneracy of the…

Biological Physics · Physics 2007-05-23 P. D. Jarvis , J. D. Bashford

In addition to variation in terms of single nucleotide polymorphisms (SNPs), whole regions ranging from several kilobases up to a megabase in length differ in copy number among individuals. These differences are referred to as Copy Number…

Genomics · Quantitative Biology 2007-09-27 Philip M. Kim , Jan O. Korbel , Xueying Chen , Mark B. Gerstein

The nature of the quantitative distribution of the 64 DNA codons in the human genome has been an issue of debate for over a decade. Some groups have proposed that the quantitative distribution of the DNA codons ordered as a rank-frequency…

Genomics · Quantitative Biology 2015-01-06 Bohdan B. Khomtchouk

An oscillation with a period of around 500 kb in guanine and cytosine content (GC%) is observed in the DNA sequence of human chromosome 21. This oscillation is localized in the rightmost one-eighth region of the chromosome, from 43.5 Mb to…

Genomics · Quantitative Biology 2007-05-23 Wentian Li , Dirk Holste

In this work it is shown that 20 canonical amino acids (AAs) within genetic code appear to be a whole system with strict distinction in Genetic Code Table (GCT) into some different quantums: 20, 23, 61 amino acid molecules. These molecules…

Biomolecules · Quantitative Biology 2019-09-23 Miloje M. Rakocevic

We updated the agent based Monte Carlo code HERITAGE that simulates human evolution within restrictive environments such as interstellar, sub-light speed spacecraft in order to include the effects of population genetics. We incorporated a…

Popular Physics · Physics 2021-02-03 F. Marin , C. Beluffi , F. Fischer

The rules that specify how the information contained in DNA codes amino acids, is called "the genetic code". Using a simplified version of the Penna nodel, we are using computer simulations to investigate the importance of the genetic code…

Genomics · Quantitative Biology 2009-11-10 E. Gultepe , M. L. Kurnaz

The evolution in coding DNA sequences brings new flexibility and freedom to the codon words, even as the underlying nucleotides get significantly ordered. These curious contra-rules of gene organisation are observed from the distribution of…

Biological Physics · Physics 2007-05-23 Sujay Chattopadhyay , William A. Kanner , Jayprokas Chakrabarti