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Receptor-mediated endocytosis is an ubiquitous process through which cells internalize biological or synthetic nanoscale objects, including viruses, unicellular parasites, and nanomedical vectors for drug or gene delivery. In passive…

Biological Physics · Physics 2018-09-19 Lorenzo Di Michele , Pritam Kumar Jana , Bortolo Matteo Mognetti

Different types of interactions coexist and coevolve to shape the structure and function of a multiplex network. We propose here a general class of growth models in which the various layers of a multiplex network coevolve through a set of…

Physics and Society · Physics 2014-10-15 Vincenzo Nicosia , Ginestra Bianconi , Vito Latora , Marc Barthelemy

Complex networks have certain properties that distinguish them from their respective uniform or regular counterparts. One of these properties is the variation of topological properties along different hierarchical levels. In this work, we…

Pattern Formation and Solitons · Physics 2023-06-19 Alexandre Benatti , Luciano da Fontoura Costa

The more we learn about the cytoplasm of cells, the more we realise that the cytoplasm is not uniform but instead is highly inhomogeneous. In any inhomogeneous solution, there are concentration gradients, and particles move either up or…

Subcellular Processes · Quantitative Biology 2019-04-03 Richard P. Sear

In this paper, we derive a new chemotaxis model with degenerate diffusion and density-dependent chemotactic sensitivity, and we provide a more realistic description of cell migration process for its early and late stages. Different from the…

Analysis of PDEs · Mathematics 2023-07-19 Tianyuan Xu , Shanming Ji , Chunhua Jin , Ming Mei , Jingxue Yin

Morphological neural networks, or layers, can be a powerful tool to boost the progress in mathematical morphology, either on theoretical aspects such as the representation of complete lattice operators, or in the development of image…

Computer Vision and Pattern Recognition · Computer Science 2024-07-02 Samy Blusseau

Trafficking of glutamate receptors into and out of synapses is critically involved in the plasticity of excitatory synaptic transmission. Endocytosis and exocytosis of receptors have initially been thought to account alone for this…

Optics · Physics 2007-05-23 Laurent Cognet , Laurent Groc , Brahim Lounis , Daniel Choquet

Endocytosis underlies many cellular functions including signaling and nutrient uptake. The endocytosed cargo gets redistributed across a dynamic network of endosomes undergoing fusion and fission. Here, a theoretical approach is reviewed…

Subcellular Processes · Quantitative Biology 2014-12-04 Lionel Foret , Lutz Brusch , Frank Jülicher

The function of a real network depends not only on the reliability of its own components, but is affected also by the simultaneous operation of other real networks coupled with it. Robustness of systems composed of interdependent network…

Physics and Society · Physics 2015-07-10 Filippo Radicchi

Recent experimental studies have demonstrated that cellular motion can be directed by topographical gradients, such as those resulting from spatial variations in the features of a micropatterned substrate. This phenomenon, known as…

The optimal use of resources has motivated the engineering community to employ controlled distribution of material within their structural designs, often relying on cellular and lattice porous structures. In this research work, a…

Materials Science · Physics 2022-07-15 A. E Gomez-Ovalle

There are three fundamental physical processes that gives rise to the morphology of a surface: deposition, surface diffusion and desorption. The characteristics of the interfaces generated by the combination of deposition and surface…

Statistical Mechanics · Physics 2007-05-23 Juan R. Sanchez

We study a continuum model of dislocation transport in order to investigate the formation of heterogeneous dislocation patterns. We propose a physical mechanism which relates the formation of heterogeneous patterns to the dynamics of a…

Materials Science · Physics 2018-08-29 Ronghai Wu , Daniel Tüzes , Péter Dusán Ispánovity , István Groma , Michael Zaiser

Ion transport in biological tissues is crucial in the study of many biological and pathological problems. Some multi-cellular structures, like smooth muscles on the vessel walls, could be treated as periodic bi-domain structures, which…

Analysis of PDEs · Mathematics 2021-03-11 Chun Xiao , Xingye Yue , Huaxiong Huang , Shixin Xu

A major challenge in flow through porous media is to better understand the link between microstructure and macroscale flow and transport. For idealised microstructures, the mathematical framework of homogenisation theory can be used for…

The migratory dynamics of cells can be influenced by the complex micro-environment through which they move. It remains unclear how the motility machinery of confined cells responds and adapts to their micro-environment. Here, we propose a…

Biological Physics · Physics 2023-12-04 Johannes Flommersfeld , Stefan Stöberl , Omar Shah , Joachim O. Rädler , Chase P. Broedersz

The intentional growth of metastable surface structures of organic molecules adsorbed on inorganic substrates is a challenging task. It is usually unclear which kinetic mechanism leads to the metastable surface polymorph after a deposition…

Materials Science · Physics 2025-07-18 Simon B. Hollweger , Anna Werkovits , Oliver T. Hofmann

We consider a partial differential equation model for the growth of heterogeneous cell populations subdivided into multiple distinct discrete phenotypes. In this model, cells preferentially move towards regions where they feel less…

Analysis of PDEs · Mathematics 2025-04-04 José A. Carrillo , Tommaso Lorenzi , Fiona R. Macfarlane

Transition points mark qualitative changes in the macroscopic properties of large complex systems. Explosive transitions, exhibiting properties of both continuous and discontinuous phase transitions, have recently been uncovered in network…

Physics and Society · Physics 2021-06-01 Nora Molkenthin , Malte Schröder , Marc Timme

Growth pattern dynamics lie at the heart of morphogenesis. Here, we investigate the growth of plant leaves. We compute the conformal transformation that maps the contour of a leaf at a given stage onto the contour of the same leaf at a…

Tissues and Organs · Quantitative Biology 2016-11-23 Karen Alim , Shahaf Armon , Boris I. Shraiman , Arezki Boudaoud
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