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We introduce HyperDiffusionFields (HyDiF), a framework that models 3D molecular conformers as continuous fields rather than discrete atomic coordinates or graphs. At the core of our approach is the Molecular Directional Field (MDF), a…

Machine Learning · Computer Science 2025-10-22 Sudarshan Babu , Phillip Lo , Xiao Zhang , Aadi Srivastava , Ali Davariashtiyani , Jason Perera , Michael Maire , Aly A. Khan

Motivation: DNA methylation is an intensely studied epigenetic mark, yet its functional role is incompletely understood. Attempts to quantitatively associate average DNA methylation to gene expression yield poor correlations outside of the…

Genomics · Quantitative Biology 2016-11-17 Chantriolnt-Andreas Kapourani , Guido Sanguinetti

In 2D+3D facial expression recognition (FER), existing methods generate multi-view geometry maps to enhance the depth feature representation. However, this may introduce false estimations due to local plane fitting from incomplete point…

Computer Vision and Pattern Recognition · Computer Science 2020-11-18 Yang Jiao , Yi Niu , Trac D. Tran , Guangming Shi

Guiding Vector Fields (GVFs) are a powerful tool for robotic path following. However, classical methods assume smooth, ordered curves and fail when paths are unordered, multi-branch, or generated by probabilistic models. We propose a…

Robotics · Computer Science 2026-04-28 Zirui Chen , Shiliang Guo , Shiyu Zhao

Proteins populate a manifold in the high-dimensional sequence space whose geometrical structure guides their natural evolution. Leveraging recently-developed structure prediction tools based on transformer models, we first examine the…

Biomolecules · Quantitative Biology 2023-11-13 A. Zambon , R. Zecchina , G. Tiana

A good feature representation is a determinant factor to achieve high performance for many machine learning algorithms in terms of classification. This is especially true for techniques that do not build complex internal representations of…

Neural and Evolutionary Computing · Computer Science 2019-08-22 Noëlie Cherrier , Jean-Philippe Poli , Maxime Defurne , Franck Sabatié

Image blending aims to combine multiple images seamlessly. It remains challenging for existing 2D-based methods, especially when input images are misaligned due to differences in 3D camera poses and object shapes. To tackle these issues, we…

Computer Vision and Pattern Recognition · Computer Science 2023-08-17 Hyunsu Kim , Gayoung Lee , Yunjey Choi , Jin-Hwa Kim , Jun-Yan Zhu

Matched Field Processing (MFP) locates the underwater sources by matching the received data with the replica vectors, which could be regarded as a generalized beamformer. In this paper, the MFP method is combined with a recently developed…

Signal Processing · Electrical Eng. & Systems 2022-01-11 Peng Xiao , Lingji Xu , Liya Xu , Jianmin Yang , Qing Hu

Predicting the nonlinear evolution of cosmic structure from initial conditions is typically approached using Lagrangian, particle-based methods. These techniques excel in terms of tracking individual trajectories, but they might not be…

Cosmology and Nongalactic Astrophysics · Physics 2026-02-11 Marion Ullmo , Nabila Aghanim , Aurélien Decelle , Miguel Aragon-Calvo

Recent advances in Spatial Transcriptomics (ST) pair histology images with spatially resolved gene expression profiles, enabling predictions of gene expression across different tissue locations based on image patches. This opens up new…

Computer Vision and Pattern Recognition · Computer Science 2025-03-21 Aniruddha Ganguly , Debolina Chatterjee , Wentao Huang , Jie Zhang , Alisa Yurovsky , Travis Steele Johnson , Chao Chen

Cellular responses often require the fast activation or repression of specific genes, which depends on Transcription Factors (TFs) that have to quickly find the promoters of these genes within a large genome. Transcription Factors (TFs)…

Subcellular Processes · Quantitative Biology 2015-09-02 Jérôme Cartailler , Jürgen Reingruber

Strong experimental and theoretical evidence shows that transcription factors and other specific DNA-binding proteins find their sites using a two-mode search: alternating between 3D diffusion through the cell and 1D sliding along the DNA.…

Biomolecules · Quantitative Biology 2008-06-11 Zeba Wunderlich , Leonid A. Mirny

In living cells, proteins combine 3D bulk diffusion and 1D sliding along the DNA to reach a target faster. This process is known as facilitated diffusion, and we investigate its dynamics in the physiologically relevant case of confined DNA.…

Soft Condensed Matter · Physics 2015-06-12 G. Foffano , D. Marenduzzo , E. Orlandini

This paper study provides a novel contribution to the field of signal processing and DL for ECG signal analysis by introducing a new feature representation method for ECG signals. The proposed method is based on transforming time frequency…

Signal Processing · Electrical Eng. & Systems 2023-08-07 Youssef Elmir , Yassine Himeur , Abbes Amira

We study by simulation the effect of the diffusive motion of repressor molecules on the noise in mRNA and protein levels in the case of a repressed gene. We find that spatial fluctuations due to diffusion can drastically enhance the noise…

Molecular Networks · Quantitative Biology 2007-05-23 Jeroen S. van Zon , Marco J. Morelli , Sorin Tanase-Nicola , Pieter Rein ten Wolde

While 2D generative adversarial networks have enabled high-resolution image synthesis, they largely lack an understanding of the 3D world and the image formation process. Thus, they do not provide precise control over camera viewpoint or…

Computer Vision and Pattern Recognition · Computer Science 2021-03-31 Katja Schwarz , Yiyi Liao , Michael Niemeyer , Andreas Geiger

The advent of new experimental genomic technologies and the massive increase of DNA sequence information is helping researchers better understand how our genes work. Recently, experiments on mRNA abundance (gene expression) have revealed…

Biomolecules · Quantitative Biology 2009-11-10 T. Ochiai , J. C. Nacher , T. Akutsu

Neural Radiance Fields (NeRF) has been wildly applied to various tasks for its high-quality representation of 3D scenes. It takes long per-scene training time and per-image testing time. In this paper, we present EfficientNeRF as an…

Computer Vision and Pattern Recognition · Computer Science 2022-06-03 Tao Hu , Shu Liu , Yilun Chen , Tiancheng Shen , Jiaya Jia

This paper presents a novel, automated, generative adversarial networks (GAN) based synthetic feeder generation mechanism, abbreviated as FeederGAN. FeederGAN digests real feeder models represented by directed graphs via a deep learning…

Systems and Control · Electrical Eng. & Systems 2020-10-13 Ming Liang , Yao Meng , Jiyu Wang , David Lubkeman , Ning Lu

Approximating wind flows using computational fluid dynamics (CFD) methods can be time-consuming. Creating a tool for interactively designing prototypes while observing the wind flow change requires simpler models to simulate faster. Instead…

Computer Vision and Pattern Recognition · Computer Science 2022-01-05 Henrik Hoeiness , Kristoffer Gjerde , Luca Oggiano , Knut Erik Teigen Giljarhus , Massimiliano Ruocco