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Worldwide, many millions of people die suddenly and unexpectedly each year, either with or without a prior history of cardiovascular disease. Such events are sparse (once in a lifetime), many victims will not have had prior investigations…

Machine Learning · Computer Science 2023-09-06 Yola Jones , Fani Deligianni , Jeff Dalton , Pierpaolo Pellicori , John G F Cleland

Model averaging combines forecasts obtained from a range of models, and it often produces more accurate forecasts than a forecast from a single model. The crucial part of forecast accuracy improvement in using the model averaging lies in…

Applications · Statistics 2018-10-01 Han Lin Shang , Steven Haberman

In recent we introduced, developed and established a new concept, model, methodology and principle for studying human longevity in terms of demographic basis. We call the new model the "Weon model", which is a general model modified from…

Populations and Evolution · Quantitative Biology 2007-05-23 Byung Mook Weon

The risk of dying increases exponentially with age, in humans as well as in many other species. This increase is often attributed to the "accumulation of damage" known to occur in many biological structures and systems. The aim of this…

Populations and Evolution · Quantitative Biology 2020-07-01 Anders Ledberg

We succeeded in obtaining exact results of the bit-string model of biological aging for populations whose individuals breed only once. These results are in excellent agreement with those obtained through computer simulations. In addition,…

adap-org · Physics 2009-10-28 T. J. P. Penna , S. Moss de Oliveira

Mortality forecasting plays a pivotal role in insurance and financial risk management of life insurers, pension funds, and social securities. Mortality data is usually high-dimensional in nature and favors factor model approaches to…

Applications · Statistics 2021-12-10 Lingyu He , Fei Huang , Yanrong Yang

This note presents an Agent-Based Model (ABM) with Monte Carlo sampling, designed to simulate the behaviour of a population of objects over time. The model incorporates damage functions with the risk parameters of the ABC framework to…

Computers and Society · Computer Science 2024-07-02 Josep Grau-Bové , Miriam Andrews

We report a new system of artificial life called Lenia (from Latin lenis "smooth"), a two-dimensional cellular automaton with continuous space-time-state and generalized local rule. Computer simulations show that Lenia supports a great…

Cellular Automata and Lattice Gases · Physics 2021-07-12 Bert Wang-Chak Chan

Complex biological processes are usually experimented along time among a collection of individuals. Longitudinal data are then available and the statistical challenge is to better understand the underlying biological mechanisms. The…

Statistics Theory · Mathematics 2015-06-11 Pierre Barbillon , Célia Barthélémy , Adeline Samson

In this paper we present a novel tool to evaluate problem solving systems. Instead of using a system to solve a problem, we suggest using the problem to evaluate the system. By finding a numerical representation of a problem's complexity,…

Neural and Evolutionary Computing · Computer Science 2007-05-23 Goren Gordon , Uri Einziger-Lowicz

We introduce a generic model for spouse's pensions. The generic model allows for the modeling of various types of spouse's pensions with payments commencing at the death of the insured. We derive abstract formulas for cashflows and…

Risk Management · Quantitative Finance 2015-12-07 Alexander Sokol

Changes of mind can become less likely the longer an agent has adopted a given opinion state. This resilience or inertia to change has been called ``aging''. We perform a comparative study of the effects of aging on the critical behavior of…

Physics and Society · Physics 2024-08-01 Jaume Llabres , Sara Oliver-Bonafoux , Celia Anteneodo , Raul Toral

Human life expectancy has dramatically improved over the course of the last century. Although this reflects a global improvement in sanitation and medical care, this also implies that more people suffer from diseases that typically manifest…

Other Quantitative Biology · Quantitative Biology 2022-07-11 Alexis Rapin , Maroun Bou Sleiman , Johan Auwerx

A modeling formalism is proposed for the description and study of living and life-like systems. It provides an abstract conceptual model framework for real life and evolution of biological organisms. It is proposed, that this model…

Populations and Evolution · Quantitative Biology 2013-06-14 Margareta Segerståhl

We consider the so-called prion equation with the general incidence term introduced in [Greer et al., 2007], and we investigate the stability of the steady states. The method is based on the reduction technique introduced in [Gabriel,…

Analysis of PDEs · Mathematics 2019-02-28 Pierre Gabriel

A one dimensional non-equilibrium stochastic model is proposed where each site of the lattice is occupied by a particle, which may be of type A or B. The time evolution of the model occurs through three processes: autocatalytic generation…

Statistical Mechanics · Physics 2007-05-23 Wellington G. Dantas , Armando Ticona , Jurgen F. Stilck

A widely-used model for determining the long-term health impacts of public health interventions, often called a "multistate lifetable", requires estimates of incidence, case fatality, and sometimes also remission rates, for multiple…

Applications · Statistics 2023-03-23 Christopher Jackson , Belen Zapata-Diomedi , James Woodcock

This paper develops a point-mutation model describing the evolutionary dynamics of a population of adult stem cells. Such a model may prove useful for quantitative studies of tissue aging and the emergence of cancer. We consider two modes…

Tissues and Organs · Quantitative Biology 2009-11-10 Emmanuel Tannenbaum , James L. Sherley , Eugene I. Shakhnovich

In the seminal work [5], Ben Arous and \v{C}ern\'y give a general characterization of aging for trap models in terms of $\alpha$-stable subordinators with $\alpha \in (0,1)$. Some of the important examples that fall into this universality…

Probability · Mathematics 2013-12-05 Onur Gün

We review the most striking experimental results on aging in a variety of disordered systems, which reveal similar features but also important differences. We argue that a generic model that reproduce many of these features is that of {\it…

Condensed Matter · Physics 2007-05-23 Jean-Philippe Bouchaud
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