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One of the famous results of network science states that networks with heterogeneous connectivity are more susceptible to epidemic spreading than their more homogeneous counterparts. In particular, in networks of identical nodes it has been…

Physics and Society · Physics 2015-08-05 Hui Yang , Ming Tang , Thilo Gross

Clustering is a difficult and widely-studied data mining task, with many varieties of clustering algorithms proposed in the literature. Nearly all algorithms use a similarity measure such as a distance metric (e.g. Euclidean distance) to…

Neural and Evolutionary Computing · Computer Science 2019-10-24 Andrew Lensen , Bing Xue , Mengjie Zhang

With complex networks emerging as an effective tool to tackle multidisciplinary problems, models of network generation have gained an importance of their own. These models allow us to extensively analyze the data obtained from real-world…

Physics and Society · Physics 2018-09-05 G. Kashyap , G. Ambika

In this paper, a random clique network model to mimic the large clustering coefficient and the modular structure that exist in many real complex networks, such as social networks, artificial networks, and protein interaction networks, is…

Physics and Society · Physics 2017-05-05 Yi-Min Ding , Jun Meng , Jing-Fang Fan , Fang-Fu Ye , Xiao-Song Chen

Site-specific recombination on supercoiled circular DNA molecules can yield a variety of knots and catenanes. Twist knots are some of the most common conformations of these products and they can act as substrates for further rounds of…

Quantitative Methods · Quantitative Biology 2011-06-23 Karin Valencia , Dorothy Buck

We consider character sequences evolving on a phylogenetic tree under the TKF91 model. We show that as the sequence lengths tend to infinity the the topology of the phylogenetic tree and the edge lengths are determined by any one of (a) the…

Genomics · Quantitative Biology 2007-05-23 Bhalchandra D. Thatte

Graphs can be used to effectively represent complex data structures. Learning these irregular data in graphs is challenging and still suffers from shallow learning. Applying deep learning on graphs has recently showed good performance in…

Machine Learning · Computer Science 2020-09-16 Thosini Bamunu Mudiyanselage , Xiujuan Lei , Nipuna Senanayake , Yanqing Zhang , Yi Pan

We derive exact equations for the spectral density of sparse networks with an arbitrary distribution of the number of single edges and triangles per node. These equations enable a systematic investigation of the effect of clustering on the…

Disordered Systems and Neural Networks · Physics 2025-01-29 Tuan Minh Pham , Thomas Peron , Fernando L. Metz

A model of correlated random networks is examined, i.e. networks with correlations between the degrees of neighboring nodes. These nodes do not necessarily have to be direct neighbors, the maximum range of the correlations can be…

Statistical Mechanics · Physics 2007-05-23 W. Pietsch

We study aggregation as a mechanism for the creation of complex networks. In this evolution process vertices merge together, which increases the number of highly connected hubs. We study a range of complex network architectures produced by…

Statistical Mechanics · Physics 2009-11-10 M. J. Alava , S. N. Dorogovtsev

Many innovations are inspired by past ideas in a non-trivial way. Tracing these origins and identifying scientific branches is crucial for research inspirations. In this paper, we use citation relations to identify the descendant chart,…

Physics and Society · Physics 2015-05-30 S. Gualdi , C. H. Yeung , Y. -C. Zhang

The study of networks has grown into a substantial interdisciplinary endeavour that encompasses myriad disciplines in the natural, social, and information sciences. Here we introduce a framework for constructing taxonomies of networks based…

Data Analysis, Statistics and Probability · Physics 2012-05-21 Jukka-Pekka Onnela , Daniel J. Fenn , Stephen Reid , Mason A. Porter , Peter J. Mucha , Mark D. Fricker , Nick S. Jones

We investigate gene interaction networks in various cancer cells by spectral analysis of the adjacency matrices. We observe localization of the networks on hub genes which have extraordinarily many links. The eigenvector centralities take…

Molecular Networks · Quantitative Biology 2019-09-25 Ayumi Kikkawa

Recent tumor genome sequencing confirmed that one tumor often consists of multiple cell subpopulations (clones) which bear different, but related, genetic profiles such as mutation and copy number variation profiles. Thus far, one tumor has…

Molecular Networks · Quantitative Biology 2014-09-09 Edwin Wang , Jinfeng Zou , Naif Zaman , Lenore K. Beitel , Mark Trifiro , Miltiadis Paliouras

Individual cancer cells carry a bewildering number of distinct genomic alterations i.e., copy number variations and mutations, making it a challenge to uncover genomic-driven mechanisms governing tumorigenesis. Here we performed…

We develop novel hierarchical reciprocal graphical models to infer gene networks from heterogeneous data. In the case of data that can be naturally divided into known groups, we propose to connect graphs by introducing a hierarchical prior…

Methodology · Statistics 2018-01-23 Yang Ni , Peter Mueller , Yitan Zhu , Yuan Ji

Inferring gene regulatory networks (GRNs) from single-cell RNA sequencing (scRNA-seq) data is a complex challenge that requires capturing the intricate relationships between genes and their regulatory interactions. In this study, we tackle…

Machine Learning · Computer Science 2024-07-26 Sindhura Kommu , Yizhi Wang , Yue Wang , Xuan Wang

A fundamental property of complex networks is the tendency for edges to cluster. The extent of the clustering is typically quantified by the clustering coefficient, which is the probability that a length-2 path is closed, i.e., induces a…

Social and Information Networks · Computer Science 2018-05-23 Hao Yin , Austin R. Benson , Jure Leskovec

Congruence theory has many applications in physical, social, biological and technological systems. Congruence arithmetic has been a fundamental tool for data security and computer algebra. However, much less attention was devoted to the…

Number Theory · Mathematics 2016-03-21 Xiao-Yong Yan , Wen-Xu Wang , Guan-Rong Chen , Ding-Hua Shi

Interest in the inference of evolutionary networks relating species or populations has grown with the increasing recognition of the importance of hybridization, gene flow and admixture, and the availability of large-scale genomic data.…

Populations and Evolution · Quantitative Biology 2024-07-23 John A. Rhodes , Hector Banos , Jingcheng Xu , Cécile Ané