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In systems biology, it is common to measure biochemical entities at different levels of the same biological system. One of the central problems for the data fusion of such data sets is the heterogeneity of the data. This thesis discusses…

Genomics · Quantitative Biology 2019-08-27 Yipeng Song

In systems biology, it is becoming increasingly common to measure biochemical entities at different levels of the same biological system. Hence, data fusion problems are abundant in the life sciences. With the availability of a multitude of…

We systematically examine all the tight-binding parameters pertinent to charge transfer along DNA. The $\pi$ molecular structure of the four DNA bases (adenine, thymine, cytosine, and guanine) is investigated by using the linear combination…

Biological Physics · Physics 2010-08-20 L. G. D. Hawke , G. Kalosakas , C. Simserides

Many materials, processes, and structures in science and engineering have important features at multiple scales of time and/or space; examples include biological tissues, active matter, oceans, networks, and images. Explicitly extracting,…

Fluid Dynamics · Physics 2021-01-12 Daniel Floryan , Michael D. Graham

The standard model of large scale structure is considered, in which the structure originates as a Gaussian adiabatic density perturbation with a nearly scale invariant spectrum. The basic theoretical tool of cosmological perturbation theory…

Astrophysics · Physics 2007-05-23 David H Lyth , Andrew R Liddle

We discuss correlation properties of a general mass density field introducing a classification of structures based on their complexity. Standard cosmological models for primordial mass fluctuations are characterized by a sort of large-scale…

Astrophysics · Physics 2009-11-10 Francesco Sylos Labini , Andrea Gabrielli

The spatial distribution of DNA base sequence A, C, G and T exhibit selfsimilar fractal fluctuations and the corresponding power spectra follow inverse power law form, which implies the following: (1) A scale invariant eddy continuum,…

General Physics · Physics 2007-05-23 A. M. Selvam

Spatial fluctuations of guanine and cytosine base content (GC%) are studied by spectral analysis for the complete set of human genomic DNA sequences. We find that (i) the 1/f^alpha decay is universally observed in the power spectra of all…

Genomics · Quantitative Biology 2007-05-23 Wentian Li , Dirk Holste

In this paper we treat some fractal and statistical features of the DNA sequences. First, a fractal record model of DNA sequence is proposed by mapping DNA sequences to integer sequences, followed by R/S analysis of the model and…

Biological Physics · Physics 2018-01-17 Zu-Guo Yu , Guo-Yi Chen

Hyperuniform many-body systems in $d$-dimensional Euclidean space are characterized by completely suppressed (normalized) infinite-wavelength density fluctuations, and appear to be endowed with novel exotic physical properties. In this…

Soft Condensed Matter · Physics 2021-06-09 Duyu Chen , Yu Zheng , Chia-Hao Lee , Sangmin Kang , Wenjuan Zhu , Houlong Zhuang , Pinshane Y. Huang , Yang Jiao

Although theories regarding the role of sequence-specific DNA resonance in biology have abounded for over 40 years, the published evidence for it is lacking. Here, the authors reasoned that for sustained resonance signaling, the number of…

Other Quantitative Biology · Quantitative Biology 2019-10-28 Ivan Savelev , Max Myakishev-Rempel

We study a scenario for the very early universe in which there is a fast phase transition from a non-geometric, high temperature phase to a low temperature, geometric phase described by a classical solution to the Einstein equations. In…

Astrophysics · Physics 2008-11-26 Joao Magueijo , Lee Smolin , Carlo R. Contaldi

In this paper the question about statistical properties of block--hierarchical random matrices is raised for the first time in connection with structural characteristics of random hierarchical networks obtained by mipmapping procedure. In…

Disordered Systems and Neural Networks · Physics 2015-05-13 V. A. Avetisov , A. V. Chertovich , S. K. Nechaev , O. A. Vasilyev

An idea to analyze the fluctuational mode or/and spectrum of water molecules in an inhomogeneous environment around a biomolecule such as protein and DNA is proposed based on the generalized Langevin equation (GLE) for water interacting…

Statistical Mechanics · Physics 2022-07-18 Fumio Hirata

The human genome contains repetitive DNA at different level of sequence length, number and dispersion. Highly repetitive DNA is particularly rich in homo-- and di--nucleotide repeats, while middle repetitive DNA is rich of families of…

Genomics · Quantitative Biology 2009-11-11 Francesco Piazza , Pietro Lio

In a class of heterogeneous random networks, where each node dynamics is a random dynamical system, interacting with neighbor nodes via a random coupling function, we characterize the hub behavior as the mean-field, subject to statistically…

Dynamical Systems · Mathematics 2025-06-25 Zheng Bian , Jeroen S. W. Lamb , Tiago Pereira

Using a well defined soft model glass in the framework of Molecular Dynamics simulations, the inherent structures are probed by means of a recently developed deformation protocol that aims to capture the Dynamical Heterogeneities (DH), as…

Disordered Systems and Neural Networks · Physics 2013-02-15 F. Leonforte

We applied coherence analysis to molecular dynamics simulations of the plant protein crambin, a thionin storage protein found in Abyssinian cabbage. Coherence analysis was developed by engineers to identify linear interactions, without…

Biomolecules · Quantitative Biology 2023-05-03 Stanley Nicholson , David Minh , Robert Eisenberg

We develop a picture of dipole-nucleus (namely dilute-dense) and dipole-dipole (dilute-dilute) scattering in the high-energy regime based on the analysis of the fluctuations in the quantum evolution. We emphasize the difference in the…

High Energy Physics - Phenomenology · Physics 2015-06-23 Stephane Munier

Granular simulations are used to probe the particle scale dynamics at short, intermediate, and long time scales for gravity driven, dense granular flows down an inclined plane. On approach to the angle of repose, where motion ceases, the…

Soft Condensed Matter · Physics 2009-11-11 L. E. Silbert