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We propose a mean-field model for describing the averaged properties of a class of stochastic diffusion-limited growth systems. We then show that this model exhibits a morphology transition from a dense-branching structure with a convex…

patt-sol · Physics 2009-10-28 Yuhai Tu , Herbert Levine

The Price equation partitions total evolutionary change into two components. The first component provides an abstract expression of natural selection. The second component subsumes all other evolutionary processes, including changes during…

Populations and Evolution · Quantitative Biology 2012-05-21 Steven A. Frank

Natural selection acts on traits at different scales, often with opposing consequences. This article identifies the particular forces that act at each scale and how those forces combine to determine the overall evolutionary outcome. A…

Populations and Evolution · Quantitative Biology 2025-10-30 Steven A. Frank

In ecology and population dynamics, gene-flow refers to the transfer of a trait from one population to another. This phenomenon appears in studying the evolution of social features, such as languages. From the mathematical point of view,…

Optimization and Control · Mathematics 2021-10-22 Idriss Mazari , Domenec Ruiz-Balet , Enrique Zuazua

Many socio-economic and biological processes can be modeled as systems of interacting individuals. The behaviour of such systems can be often described within game-theoretic models. In these lecture notes, we introduce fundamental concepts…

Populations and Evolution · Quantitative Biology 2013-05-30 Jacek Miekisz

Fundamental properties of macroscopic gene-mating dynamic evolutionary systems are investigated. We focus on a single locus, any number of alleles in a two-gender dioecious population, for a large class of systems within population…

Populations and Evolution · Quantitative Biology 2020-07-22 Juven Wang , Jiunn-Wei Chen

The predominant success of diffusion models in generative modeling has spurred significant interest in understanding their theoretical foundations. In this work, we propose a feature learning framework aimed at analyzing and comparing the…

Machine Learning · Statistics 2025-03-04 Andi Han , Wei Huang , Yuan Cao , Difan Zou

Naturally evolving proteins gradually accumulate mutations while continuing to fold to thermodynamically stable native structures. This process of neutral protein evolution is an important mode of genetic change, and forms the basis for the…

Populations and Evolution · Quantitative Biology 2007-05-23 Jesse D Bloom , Alpan Raval , Claus O Wilke

This paper develops the notion and properties of the generalized principal eigenvalue for an elliptic system coupling an equation in a plane with one on a line in this plane, together with boundary conditions that express exchanges taking…

Analysis of PDEs · Mathematics 2018-11-01 Henri Berestycki , Romain Ducasse , Luca Rossi

Variation and selection are the core principles of Darwinian evolution, yet quantitatively relating the diversity of a population to its capacity to respond to selection is challenging. Here, we examine this problem at a molecular level in…

Populations and Evolution · Quantitative Biology 2016-04-27 Sébastien Boyer , Dipanwita Biswas , Ananda Kumar Soshee , Natale Scaramozzino , Clément Nizak , Olivier Rivoire

In the spirit of the many recent simple models of evolution inspired by statistical physics, we put forward a simple model of the evolution of such models. Like its objects of study, it is (one supposes) in principle testable and capable of…

adap-org · Physics 2007-05-23 Cosma Rohilla Shalizi , William A. Tozier

The spreading of evolutionary novelties across populations is the central element of adaptation. Unless population are well-mixed (like bacteria in a shaken test tube), the spreading dynamics not only depends on fitness differences but also…

Populations and Evolution · Quantitative Biology 2015-06-19 Oskar Hallatschek , Daniel S. Fisher

We consider the general properties of the quasispecies dynamical system from the standpoint of its evolution and stability. Vector field analysis as well as spectral properties of such system has been studied. Mathematical modelling of the…

Condensed Matter · Physics 2007-05-23 V. V. Gafiychuk , A. K. Prykarpatsky

We describe the time evolution of gene expression levels by using a time translational matrix to predict future expression levels of genes based on their expression levels at some initial time. We deduce the time translational matrix for…

Statistical Mechanics · Physics 2009-11-07 Neal S. Holter , Amos Maritan , Marek Cieplak , Nina V. Fedoroff , Jayanth R. Banavar

A simple model of macroevolution is proposed exhibiting both the property of punctuated equilibrium and the dynamics of potentialities for different species to evolve towards increasingly higher complexity. It is based on the phenomenon of…

Biological Physics · Physics 2007-05-23 Siegfried Fussy , Gerhard Groessing , Herbert Schwabl

Evolution by Natural Selection is a process by which progeny inherit some properties from their progenitors with small variation. These properties are subject to Natural Selection and are called adaptive traits and carriers of the latter…

Analysis of PDEs · Mathematics 2024-01-29 Gonzalo Galiano , Yosef Cohen

In this paper, we consider domain-invariant deep learning by explicitly modeling domain shifts with only a small amount of domain-specific parameters in a Convolutional Neural Network (CNN). By exploiting the observation that a…

Machine Learning · Computer Science 2020-09-30 Ze Wang , Xiuyuan Cheng , Guillermo Sapiro , Qiang Qiu

We study the large population limit of the Moran process, assuming weak-selection, and for different scalings. Depending on the particular choice of scalings, we obtain a continuous model that may highlight the genetic-drift (neutral…

Populations and Evolution · Quantitative Biology 2013-01-21 Fabio A. C. C. Chalub , Max O. Souza

The diffusion-controlled limit of reaction times for site-specific DNA-binding proteins is derived from first principles. We follow the generally accepted concept that a protein propagates via two competitive modes, a three-dimensional…

Biological Physics · Physics 2009-11-11 Konstantin V. Klenin , Holger Merlitz , Joerg Langowski , Chen-Xu Wu

Mathematical theory of selection is developed within the frameworks of general models of inhomogeneous populations with continuous time. Methods that allow us to study the distribution dynamics under natural selection and to construct…

Populations and Evolution · Quantitative Biology 2009-12-22 Georgy P. Karev