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Within bioinformatics, the textual alignment of amino acid sequences has long dominated the determination of similarity between proteins, with all that implies for shared structure, function and evolutionary descent. Despite the relative…

Quantitative Methods · Quantitative Biology 2016-02-10 Amit K Chattopadhyay , Diar Nasiev , Darren R Flower

With distributed computing and mobile applications, synchronizing diverging replicas of data structures is a more and more common problem. We use algebraic methods to reason about filesystem operations, and introduce a simplified definition…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-07-24 Elod Pal Csirmaz

Comparison and contrast are the basic means to unveil causation and learn which treatments work. To build good comparison groups, randomized experimentation is key, yet often infeasible. In such non-experimental settings, we illustrate and…

Methodology · Statistics 2024-01-30 Ambarish Chattopadhyay , Jose R. Zubizarreta

We target the problem of provably computing the equivalence between two complex expression trees. To this end, we formalize the problem of equivalence between two such programs as finding a set of semantics-preserving rewrite rules from one…

Programming Languages · Computer Science 2021-06-10 Steve Kommrusch , Théo Barollet , Louis-Noël Pouchet

The study of the topological structure of complex networks has fascinated researchers for several decades, and today we have a fairly good understanding of the types and reoccurring characteristics of many different complex networks.…

Social and Information Networks · Computer Science 2014-06-23 Matthieu Roy , Stefan Schmid , Gilles Trédan

Set similarity join is a fundamental and well-studied database operator. It is usually studied in the exact setting where the goal is to compute all pairs of sets that exceed a given similarity threshold (measured e.g. as Jaccard…

Databases · Computer Science 2018-03-05 Tobias Christiani , Rasmus Pagh , Johan Sivertsen

Using an asymmetric associative network with synchronous updating, it is possible to recall a sequence of patterns. To obtain a stable sequence generation with a large storage capacity, we introduce a threshold that eliminates the…

comp-gas · Physics 2008-02-03 F. Zertuche , R. López-Peña , H. Waelbroeck

Graph matching is the process of computing the similarity between two graphs. Depending on the requirement, it can be exact or inexact. Exact graph matching requires a strict correspondence between nodes of two graphs, whereas inexact…

Social and Information Networks · Computer Science 2022-01-13 Shri Prakash Dwivedi

Now a days, data mining and knowledge discovery methods are applied to a variety of enterprise and engineering disciplines to uncover interesting patterns from databases. The study of Sequential patterns is an important data mining problem…

Databases · Computer Science 2009-06-24 Jigyasa Bisaria , Namita Shrivastava , K. R. Pardasani

We consider universal inference in variance components models, focusing on settings where the parameter is near or at the boundary of the parameter set. Two cases, which are not handled by existing state-of-the-art methods, are of…

Methodology · Statistics 2025-09-03 Yiqiao Zhang , Karl Oskar Ekvall , Aaron J. Molstad

A central problem in comparative genomics consists in computing a (dis-)similarity measure between two genomes, e.g. in order to construct a phylogeny. All the existing measures are defined on genomes without duplicates. However, we know…

Quantitative Methods · Quantitative Biology 2008-12-18 Sébastien Angibaud , Guillaume Fertin , Irena Rusu , Annelyse Thevenin , Stéphane Vialette

This paper presents a new, parallel implementation of clustering and demonstrates its utility in greatly speeding up the process of identifying homologous proteins. Clustering is a technique to reduce the number of comparison needed to find…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-08-29 Stuart Byma , Akash Dhasade , Adrian Altenhoff , Christophe Dessimoz , James R. Larus

Transformer architectures have facilitated the development of large-scale and general-purpose sequence models for prediction tasks in natural language processing and computer vision, e.g., GPT-3 and Swin Transformer. Although originally…

Machine Learning · Computer Science 2023-06-27 Muning Wen , Runji Lin , Hanjing Wang , Yaodong Yang , Ying Wen , Luo Mai , Jun Wang , Haifeng Zhang , Weinan Zhang

A novel non-linear approach to fast and effective comparison of sequences is presented, compared to the traditional cross-correlation operator, and illustrated with respect to DNA sequences.

Computer Vision and Pattern Recognition · Computer Science 2007-05-23 Luciano da Fontoura Costa

A supersequence over a finite set is a sequence that contains as subsequence all permutations of the set. This paper defines an infinite array of methods to create supersequences of decreasing lengths. This yields the shortest known…

Combinatorics · Mathematics 2025-01-07 Oliver Tan

Quantifying the similarity of two or more datasets has widespread applications in statistics and machine learning. The method choice is, however, difficult due to the abundance of proposed methods and the lack of neutral comparison studies,…

Methodology · Statistics 2026-04-14 Marieke Stolte , Jörg Rahnenführer , Andrea Bommert

Exact structured inference with neural network scoring functions is computationally challenging but several methods have been proposed for approximating inference. One approach is to perform gradient descent with respect to the output…

Computation and Language · Computer Science 2019-07-09 Lifu Tu , Kevin Gimpel

Traditional methods for matching in causal inference are impractical for high-dimensional datasets. They suffer from the curse of dimensionality: exact matching and coarsened exact matching find exponentially fewer matches as the input…

Machine Learning · Statistics 2026-02-12 Oscar Clivio , Fabian Falck , Brieuc Lehmann , George Deligiannidis , Chris Holmes

Measuring the similarity of short written contexts is a fundamental problem in Natural Language Processing. This article provides a unifying framework by which short context problems can be categorized both by their intended application and…

Computation and Language · Computer Science 2010-10-19 Ted Pedersen

In the course of evolution, proteins undergo important changes in their amino acid sequences, while their three-dimensional folded structure and their biological function remain remarkably conserved. Thanks to modern sequencing techniques,…

Biomolecules · Quantitative Biology 2019-10-07 Simona Cocco , Christoph Feinauer , Matteo Figliuzzi , Remi Monasson , Martin Weigt