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In genomics, pattern matching against a sequence of nucleotides plays a pivotal role for DNA sequence alignment and comparing genomes. This helps tackling some diseases, such as cancer in humans. The complexity of searching biological…

Quantitative Methods · Quantitative Biology 2017-10-04 Fereshte Mozafari , Hossein Babashah , Somayyeh Koohi , Zahra Kavehvash

Measuring the distance between data points is fundamental to many statistical techniques, such as dimension reduction or clustering algorithms. However, improvements in data collection technologies has led to a growing versatility of…

Methodology · Statistics 2022-06-20 George Bolt , Simón Lunagómez , Christopher Nemeth

A new numerical characterization of symbolic sequences is proposed. The partition of sequence based on Ke and Tong algorithm is a starting point. Algorithm decomposes original sequence into set of distinct subsequences - a patterns. The set…

Quantitative Methods · Quantitative Biology 2011-09-08 B. Kozarzewski

Sequential modelling entails making sense of sequential data, which naturally occurs in a wide array of domains. One example is systems that interact with users, log user actions and behaviour, and make recommendations of items of potential…

Information Retrieval · Computer Science 2021-09-15 Christian Hansen

Understanding the structure and dynamics of biological networks is one of the important challenges in system biology. In addition, increasing amount of experimental data in biological networks necessitate the use of efficient methods to…

Artificial Intelligence · Computer Science 2012-07-17 Mohammadreza Keyvanpour , Fereshteh Azizani

The availability of large amounts of time series data, paired with the performance of deep-learning algorithms on a broad class of problems, has recently led to significant interest in the use of sequence-to-sequence models for time series…

Machine Learning · Computer Science 2019-02-27 Vitaly Kuznetsov , Zelda Mariet

Multiple sequence alignment (MSA) has been one of the most important problems in bioinformatics for more decades and it is still heavily examined by many mathematicians and biologists. However, mostly because of the practical motivation of…

Quantitative Methods · Quantitative Biology 2015-11-17 Kristóf Takács

Conformance checking encompasses a body of process mining techniques which aim to find and describe the differences between a process model capturing the expected process behavior and a corresponding event log recording the observed…

Software Engineering · Computer Science 2022-03-29 Daniel Reißner , Abel Armas-Cervantes , Marcello La Rosa

Conformance checking is a set of process mining functions that compare process instances with a given process model. It identifies deviations between the process instances' actual behaviour ("as-is") and its modelled behaviour ("to-be").…

Software Engineering · Computer Science 2020-07-22 Sebastian Dunzer , Matthias Stierle , Martin Matzner , Stephan Baier

This paper investigates the length problem in sequence-level relative reinforcement learning. We observe that, although existing methods partially alleviate length-related phenomena, a more fundamental issue remains insufficiently…

Machine Learning · Computer Science 2026-05-26 Fei Ding , Yongkang Zhang , Runhao Liu , Yuhao Liao , Zijian Zeng , Huiming Yang , Sibo wang , Linglin Liao

The Longest Common Subsequence (LCS) problem is a fundamental problem of sequence comparison. A natural approximation to this problem is a model in which every pairs of letters of two ``sequences'' are matched independently of the other…

Disordered Systems and Neural Networks · Physics 2016-08-31 J. Boutet de Monvel

Linearizability has become the key correctness criterion for concurrent data structures, ensuring that histories of the concurrent object under consideration are consistent, where consistency is judged with respect to a sequential history…

Logic in Computer Science · Computer Science 2015-02-03 Brijesh Dongol , John Derrick

Mathematical modelling allows us to concisely describe fundamental principles in biology. Analysis of models can help to both explain known phenomena, and predict the existence of new, unseen behaviours. Model analysis is often a complex…

Quantitative Methods · Quantitative Biology 2020-08-13 Mark Blyth , Ludovic Renson , Lucia Marucci

The identification of anomalies in temporal data is a core component of numerous research areas such as intrusion detection, fault prevention, genomics and fraud detection. This article provides an experimental comparison of the novelty…

Machine Learning · Computer Science 2019-12-02 Rémi Domingues , Pietro Michiardi , Jérémie Barlet , Maurizio Filippone

This talk will review a little over a decade's research on applying certain stochastic models to biological sequence analysis. The models themselves have a longer history, going back over 30 years, although many novel variants have arisen…

Probability · Mathematics 2007-05-23 T. P. Speed

DNA sequence alignment is important today as it is usually the first step in finding gene mutation, evolutionary similarities, protein structure, drug development and cancer treatment. Covid-19 is one recent example. There are many…

Genomics · Quantitative Biology 2023-06-01 Suchindra , Preetam Nagaraj

Finding the longest common subsequence in $k$-length substrings (LCS$k$) is a recently proposed problem motivated by computational biology. This is a generalization of the well-known LCS problem in which matching symbols from two sequences…

Data Structures and Algorithms · Computer Science 2013-11-20 Sebastian Deorowicz , Szymon Grabowski

Biomolecular structure comparison not only reveals evolutionary relationships, but also sheds light on biological functional properties. However, traditional definitions of structure or sequence similarity always involve superposition or…

Quantitative Methods · Quantitative Biology 2017-07-13 Kelin Xia

Recent advances in high-throughput genomics technologies have resulted in the sequencing of large numbers of (near) complete genomes. These genome sequences are being mined for important functional elements, such as genes. They are also…

Genomics · Quantitative Biology 2007-05-23 Lior Pachter

Using a time series model to mimic an observed time series has a long history. However, with regard to this objective, conventional estimation methods for discrete-time dynamical models are frequently found to be wanting. In fact, they are…

Statistics Theory · Mathematics 2015-03-19 Yingcun Xia , Howell Tong
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