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Sequence classification algorithms, such as SVM, require a definition of distance (similarity) measure between two sequences. A commonly used notion of similarity is the number of matches between $k$-mers ($k$-length subsequences) in the…

Data Structures and Algorithms · Computer Science 2017-12-13 Muhammad Farhan , Juvaria Tariq , Arif Zaman , Mudassir Shabbir , Imdad Ullah Khan

This paper presents a new approach to statistical similarity assessment based on sequence alignment. The algorithm performs mutual matching of two random sequences by successively searching for common elements and by applying sequence…

Signal Processing · Electrical Eng. & Systems 2021-06-09 Jakub Nikonowicz , Łukasz Matuszewski , Paweł Kubczak

Graph comparison is fundamentally important for many applications such as the analysis of social networks and biological data and has been a significant research area in the pattern recognition and pattern analysis domains. Nowadays, the…

Data Structures and Algorithms · Computer Science 2015-02-27 Hamida Seba , Sofiane Lagraa , Elsen Ronando

The rapid development of high-throughput sequencing technologies has led to an explosive increase in biological sequence data, making sequence clustering a fundamental task in large-scale bioinformatics analyses. Unlike traditional…

Genomics · Quantitative Biology 2026-01-22 Simeng Zhang , Xinying Liu , Jun Lou , Mudi Jiang , Quan Zou , Zengyou He

A common problem in natural sciences is the comparison of competing models in the light of observed data. Bayesian model comparison provides a statistically sound framework for this comparison based on the evidence each model provides for…

Machine Learning · Statistics 2022-03-23 Jan Boelts

Sequence comparison is a prerequisite to virtually all comparative genomic analyses. It is often realized by sequence alignment techniques, which are computationally expensive. This has led to increased research into alignment-free…

Data Structures and Algorithms · Computer Science 2015-12-23 Maxime Crochemore , Gabriele Fici , Robert Mercaş , Solon P. Pissis

Multiple sequence alignment is a basic procedure in molecular biology, and it is often treated as being essentially a solved computational problem. However, this is not so, and here I review the evidence for this claim, and outline the…

Populations and Evolution · Quantitative Biology 2018-08-24 David A. Morrison

We survey current developments in the approximation theory of sequence modelling in machine learning. Particular emphasis is placed on classifying existing results for various model architectures through the lens of classical approximation…

Machine Learning · Computer Science 2023-02-28 Haotian Jiang , Qianxiao Li , Zhong Li , Shida Wang

Ancestral sequence reconstruction is a key task in computational biology. It consists in inferring a molecular sequence at an ancestral species of a known phylogeny, given descendant sequences at the tip of the tree. In addition to its many…

Populations and Evolution · Quantitative Biology 2022-07-27 Brandon Legried , Sebastien Roch

Sequence-to-Sequence models were introduced to tackle many real-life problems like machine translation, summarization, image captioning, etc. The standard optimization algorithms are mainly based on example-to-example matching like maximum…

Computation and Language · Computer Science 2018-09-05 Wenhu Chen , Guanlin Li , Shujie Liu , Zhirui Zhang , Mu Li , Ming Zhou

We study pattern matching problems on two major representations of uncertain sequences used in molecular biology: weighted sequences (also known as position weight matrices, PWM) and profiles (i.e., scoring matrices). In the simple version,…

Data Structures and Algorithms · Computer Science 2016-07-12 Tomasz Kociumaka , Solon P. Pissis , Jakub Radoszewski

Machine learning for data-driven diagnosis has been actively studied in medicine to provide better healthcare. Supporting analysis of a patient cohort similar to a patient under treatment is a key task for clinicians to make decisions with…

Medical Physics · Physics 2020-03-25 Rongchen Guo , Takanori Fujiwara , Yiran Li , Kelly M. Lima , Soman Sen , Nam K. Tran , Kwan-Liu Ma

A classical measure of string comparison is given by the longest common subsequence (LCS) problem on a pair of strings. We consider its generalisation, called the semi-local LCS problem, which arises naturally in many string-related…

Data Structures and Algorithms · Computer Science 2015-03-13 Alexander Tiskin

Sequence comparison is a prerequisite to virtually all comparative genomic analyses. It is often realised by sequence alignment techniques, which are computationally expensive. This has led to increased research into alignment-free…

Data Structures and Algorithms · Computer Science 2018-06-08 Panagiotis Charalampopoulos , Maxime Crochemore , Gabriele Fici , Robert Mercas , Solon P. Pissis

Sequence classification is an important data mining task in many real world applications. Over the past few decades, many sequence classification methods have been proposed from different aspects. In particular, the pattern-based method is…

Machine Learning · Computer Science 2020-12-15 Zengyou He , Guangyao Xu , Chaohua Sheng , Bo Xu , Quan Zou

Subsequence matching has appeared to be an ideal approach for solving many problems related to the fields of data mining and similarity retrieval. It has been shown that almost any data class (audio, image, biometrics, signals) is or can be…

Multimedia · Computer Science 2012-06-13 David Novak , Petr Volny , Pavel Zezula

String matching algorithm plays the vital role in the Computational Biology. The functional and structural relationship of the biological sequence is determined by similarities on that sequence. For that, the researcher is supposed to aware…

Data Structures and Algorithms · Computer Science 2014-01-30 Pandiselvam. P , Marimuthu. T , Lawrance. R

Longest common subsequence (LCS) is one of the most fundamental problems in combinatorial optimization. Apart from theoretical importance, LCS has enormous applications in bioinformatics, revision control systems, and data comparison…

Data Structures and Algorithms · Computer Science 2020-03-17 MohammadTaghi Hajiaghayi , Masoud Seddighin , Saeed Seddighin , Xiaorui Sun

Biological sequence comparison is a key step in inferring the relatedness of various organisms and the functional similarity of their components. Thanks to the Next Generation Sequencing efforts, an abundance of sequence data is now…

Machine Learning · Computer Science 2016-09-13 Dhananjay Kimothi , Akshay Soni , Pravesh Biyani , James M. Hogan

New proposed models are often compared to state-of-the-art using statistical significance testing. Literature is scarce for classifier comparison using metrics other than accuracy. We present a survey of statistical methods that can be used…

Machine Learning · Computer Science 2016-11-17 Lovedeep Gondara
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