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The Thermodynamic Formalism provides a rigorous mathematical framework to study quantitative and qualitative aspects of dynamical systems. At its core there is a variational principle corresponding, in its simplest form, to the Maximum…

Neurons and Cognition · Quantitative Biology 2020-12-30 Rodrigo Cofré , Cesar Maldonado , Bruno Cessac

The cellular Potts model (CPM) is a powerful computational method for simulating collective spatiotemporal dynamics of biological cells. To drive the dynamics, CPMs rely on physics-inspired Hamiltonians. However, as first principles remain…

Machine Learning · Computer Science 2025-02-05 Koen Minartz , Tim d'Hondt , Leon Hillmann , Jörn Starruß , Lutz Brusch , Vlado Menkovski

Neural population activity often exhibits rich variability and temporal structure. This variability is thought to arise from single-neuron stochasticity, neural dynamics on short time-scales, as well as from modulations of neural firing…

Machine Learning · Statistics 2014-10-14 Mijung Park , Jakob H. Macke

The neural mechanism of memory has a very close relation with the problem of representation in artificial intelligence. In this paper a computational model was proposed to simulate the network of neurons in brain and how they process…

Neurons and Cognition · Quantitative Biology 2020-12-02 Hui Wei

The traditional view of neural computation in the cerebral cortex holds that sensory neurons are specialized, i.e., selective for certain dimensions of sensory stimuli. This view was challenged by evidence of contextual interactions between…

Neurons and Cognition · Quantitative Biology 2022-04-26 Sergei Gepshtein , Ambarish Pawar , Sunwoo Kwon , Sergey Savel'ev , Thomas D. Albright

To fully understand, analyze, and determine the behavior of dynamical systems, it is crucial to identify their intrinsic modal coordinates. In nonlinear dynamical systems, this task is challenging as the modal transformation based on the…

Machine Learning · Computer Science 2025-03-13 Abdolvahhab Rostamijavanani , Shanwu Li , Yongchao Yang

Representation of brain network interactions is fundamental to the translation of neural structure to brain function. As such, methodologies for mapping neural interactions into structural models, i.e., inference of functional connectome…

Neurons and Cognition · Quantitative Biology 2022-03-18 Rahul Biswas , Eli Shlizerman

Thanks to novel, powerful brain activity recording techniques, we can create data-driven models from thousands of recording channels and large portions of the cortex, which can improve our understanding of brain-states neuromodulation and…

Metastable brain dynamics are characterized by abrupt, jump-like modulations so that the neural activity in single trials appears to unfold as a sequence of discrete, quasi-stationary states. Evidence that cortical neural activity unfolds…

Neurons and Cognition · Quantitative Biology 2019-06-20 Giancarlo La Camera , Alfredo Fontanini , Luca Mazzucato

Experimental manipulations perturb the neuronal activity. This phenomenon is manifested in the fMRI response. Dynamic causal model and its variants can model these neuronal responses along with the BOLD responses [1, 2, 3, 4, 5] .…

Neurons and Cognition · Quantitative Biology 2021-01-15 Sayan Nag

We present a fiber-distributed model of the reinforcing collagen of the human cornea. The model describes the basic connections between the components of the tissue by defining an elementary block (cell) and upscaling it to the physical…

Biological Physics · Physics 2023-06-28 Maria Laura De Bellis , Marcello Vasta , Alessio Gizzi , Anna Pandolfi

Human brain functional connectivity (FC) is often measured as the similarity of functional MRI responses across brain regions when a brain is either resting or performing a task. This paper aims to statistically analyze the dynamic nature…

Computer Vision and Pattern Recognition · Computer Science 2024-10-30 Mengyu Dai , Zhengwu Zhang , Anuj Srivastava

Robust characterization of dynamic causal interactions in multivariate biomedical signals is essential for advancing computational and algorithmic methods in biomedical imaging. Conventional approaches, such as Dynamic Bayesian Networks…

Signal Processing · Electrical Eng. & Systems 2026-02-17 Farwa Abbas , Wei Dai , Zoran Cvetkovic , Verity McClelland

In this paper, we present a novel general framework grounded in the factor graph theory to solve kinematic and dynamic problems for multi-body systems. Although the motion of multi-body systems is considered to be a well-studied problem and…

Robotics · Computer Science 2021-07-27 José-Luis Blanco-Claraco , Antonio Leanza , Giulio Reina

We introduce a foundational model for brain dynamics that utilizes stochastic optimal control (SOC) and amortized inference. Our method features a continuous-discrete state space model (SSM) that can robustly handle the intricate and noisy…

Machine Learning · Computer Science 2025-02-10 Joonhyeong Park , Byoungwoo Park , Chang-Bae Bang , Jungwon Choi , Hyungjin Chung , Byung-Hoon Kim , Juho Lee

We propose a data-driven approach to represent neuronal network dynamics as a Probabilistic Graphical Model (PGM). Our approach learns the PGM structure by employing dimension reduction to network response dynamics evoked by stimuli applied…

Neurons and Cognition · Quantitative Biology 2017-11-02 Hexuan Liu , Jimin Kim , Eli Shlizerman

Simplified models are a necessary steppingstone for understanding collective neural network dynamics, in particular the transitions between different kinds of behavior, whose universality can be captured by such models, without prejudice.…

Chaotic Dynamics · Physics 2022-10-25 Rashid V. Williams-García , Stam Nicolis

Representing dynamical systems through data-driven universal spaces has proven effective; however, achieving this universality for human brain activity remains a significant challenge, further aggravated by diverse cognitive states and…

Quantitative Methods · Quantitative Biology 2026-05-06 Ronghua Zheng , Chengyuan Qian , Weiyang Ding

Feed-forward neural networks consist of a sequence of layers, in which each layer performs some processing on the information from the previous layer. A downside to this approach is that each layer (or module, as multiple modules can…

Machine Learning · Computer Science 2020-10-19 Alex Lamb , Anirudh Goyal , Agnieszka Słowik , Michael Mozer , Philippe Beaudoin , Yoshua Bengio

In this paper we provide a comprehensive analysis of a structural model for the dynamics of prices of assets traded in a market originally proposed in [1]. The model takes the form of an interacting generalization of the geometric Brownian…

Statistical Finance · Quantitative Finance 2018-06-06 Kartik Anand , Jonathan Khedair , Reimer Kuehn
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