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Phylogenetic networks provide a means of describing the evolutionary history of sets of species believed to have undergone hybridization or gene flow during their evolution. The mutation process for a set of such species can be modeled as a…

Populations and Evolution · Quantitative Biology 2022-11-23 Travis Barton , Elizabeth Gross , Colby Long , Joseph Rusinko

In this paper we present a novel tool to evaluate problem solving systems. Instead of using a system to solve a problem, we suggest using the problem to evaluate the system. By finding a numerical representation of a problem's complexity,…

Neural and Evolutionary Computing · Computer Science 2007-05-23 Goren Gordon , Uri Einziger-Lowicz

Evolution is a process that is influenced by various environmental factors, e.g. the interactions between different species, genes, and biogeographical properties. Hence, it is interesting to study the combined evolutionary history of…

Quantitative Methods · Quantitative Biology 2013-08-02 Nicolas Wieseke , Matthias Bernt , Martin Middendorf

Simple stochastic models for phylogenetic trees on species have been well studied. But much paleontology data concerns time series or trees on higher-order taxa, and any broad picture of relationships between extant groups requires use of…

Populations and Evolution · Quantitative Biology 2007-08-28 David Aldous , Maxim Krikun , Lea Popovic

Since the advent of modern bioinformatics, the challenging, multifaceted problem of reconstructing phylogenetic history from biological sequences has hatched perennial statistical and algorithmic innovation. Studies of the phylogenetic…

Data Structures and Algorithms · Computer Science 2024-03-05 Matthew Andres Moreno , Santiago Rodriguez Papa , Emily Dolson

Reticulate evolutionary processes result in phylogenetic histories that cannot be modeled using a tree topology. Here, we apply methods from topological data analysis to molecular sequence data with reticulations. Using a simple example, we…

Quantitative Methods · Quantitative Biology 2015-11-05 Kevin Emmett , Raul Rabadan

Computer modelling for evolutionary systems consists in: 1) to store in the memory the individual features of each member of a large population; and 2) to update the whole system repeatedly, as time goes by, according to some prescribed…

Statistical Mechanics · Physics 2007-05-23 Paulo Murilo Castro de Oliveira

We propose a model for evolution aiming to reproduce statistical features of fossil data, in particular the distributions of extinction events, the distribution of species per genus and the distribution of lifetimes, all of which are known…

Populations and Evolution · Quantitative Biology 2008-06-06 Peter Klimek , Stefan Thurner , Rudolf Hanel

Stochastic simulation has been a powerful tool for studying the dynamics of gene regulatory networks, particularly in terms of understanding how cell-phenotype stability and fate-transitions are impacted by noisy gene expression. However,…

Molecular Networks · Quantitative Biology 2018-09-05 Margaret J. Tse , Brian K. Chu , Elizabeth L. Read

The availability of a large number of assembled genomes opens the way to study the evolution of syntenic character within a phylogenetic context. The DeCo algorithm, recently introduced by B{\'e}rard et al. allows the computation of…

Quantitative Methods · Quantitative Biology 2015-03-20 Ashok Rajaraman , Cedric Chauve , Yann Ponty

In this paper, we consider a series of events observed at spaced time intervals and present a method of representation of the series. To explain an idea, by dealing with a set of gene expression data, which could be obtained from…

Computational Complexity · Computer Science 2007-05-23 Gene Kim , MyungHo Kim

Stochastic mapping is a simulation-based method for probabilistically mapping substitution histories onto phylogenies according to continuous-time Markov models of evolution. This technique can be used to infer properties of the…

Computation · Statistics 2017-02-10 Amrit Dhar , Vladimir N. Minin

Phylogenetic comparative methods are well established tools for using inter-species variation to analyse phenotypic evolution and adaptation. They are generally hampered, however, by predominantly univariate approaches and failure to…

Populations and Evolution · Quantitative Biology 2024-12-13 Krzysztof Bartoszek

Phylogenetics is a branch of computational biology that studies the evolutionary relationships among biological entities. Its long history and numerous applications notwithstanding, inference of phylogenetic trees from sequence data remains…

Populations and Evolution · Quantitative Biology 2024-03-26 Mingyang Zhou , Zichao Yan , Elliot Layne , Nikolay Malkin , Dinghuai Zhang , Moksh Jain , Mathieu Blanchette , Yoshua Bengio

How do mammalian cells that share the same genome exist in notably distinct phenotypes, exhibiting differences in morphology, gene expression patterns, and epigenetic chromatin statuses? Furthermore how do cells of different phenotypes…

Molecular Networks · Quantitative Biology 2015-04-27 Jianhua Xing , Jin Yu , Hang Zhang , Xiao-Jun Tian

Epigenetic histone modifications play an important role in the maintenance of different cell phenotypes. The exact molecular mechanism for inheritance of the modification patterns over cell generations remains elusive. We construct a…

Genomics · Quantitative Biology 2014-03-03 Hang Zhang , Xiao-Jun Tian , Abhishek Mukhopadhyay , K. S. Kim , Jianhua Xing

We give a overview of stochastic models of evolution that have found applications in genetics, ecology and linguistics for an audience of nonspecialists, especially statistical physicists. In particular, we focus mostly on neutral models in…

Statistical Mechanics · Physics 2009-11-13 R. A. Blythe , A. J. McKane

Quantum simulations constructing probability tensors of biological multi-taxa in phylogenetic trees are proposed, in terms of positive trace preserving maps, describing evolving systems of quantum walks with multiple walkers. Basic…

Quantum Physics · Physics 2011-05-10 Demosthenes Ellinas , Peter Jarvis

Problems with solutions represented by permutations are very prominent in combinatorial optimization. Thus, in recent decades, a number of evolutionary algorithms have been proposed to solve them, and among them, those based on probability…

Neural and Evolutionary Computing · Computer Science 2023-04-06 Valentino Santucci , Josu Ceberio

We develop a stochastic calculus that makes it easy to capture a variety of predictable transformations of semimartingales such as changes of variables, stochastic integrals, and their compositions. The framework offers a unified treatment…

Probability · Mathematics 2022-01-13 Aleš Černý , Johannes Ruf