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We present a statistical model of bacterial evolution based on the coupling between codon usage and tRNA abundance. Such a model interprets this aspect of the evolutionary process as a balance between the codon homogenization effect due to…

Statistical Mechanics · Physics 2007-05-23 Franco Bagnoli , Pietro Lio'

Computer modelling for evolutionary systems consists in: 1) to store in the memory the individual features of each member of a large population; and 2) to update the whole system repeatedly, as time goes by, according to some prescribed…

Statistical Mechanics · Physics 2007-05-23 Paulo Murilo Castro de Oliveira

Epigenetic histone modifications play an important role in the maintenance of different cell phenotypes. The exact molecular mechanism for inheritance of the modification patterns over cell generations remains elusive. We construct a…

Genomics · Quantitative Biology 2014-03-03 Hang Zhang , Xiao-Jun Tian , Abhishek Mukhopadhyay , K. S. Kim , Jianhua Xing

Textual analysis of typical microbial genomes reveals that they have the statistical characteristics of a DNA sequence of a much shorter length. This peculiar property supports an evolutionary model in which a genome evolves by random…

Biological Physics · Physics 2009-11-07 L. C. Hsieh , L. F. Luo , F. M. Ji , H. C. Lee

We introduce and analyze a within-host dynamical model of the coevolution between rapidly mutating pathogens and the adaptive immune response. Pathogen mutation and a homeostatic constraint on lymphocytes both play a role in allowing the…

Populations and Evolution · Quantitative Biology 2014-08-06 Kimberly J. Schlesinger , Sean P. Stromberg , Jean M. Carlson

In this paper we consider a microscopic model of a simple ecosystem. The basic ingredients of this model are individuals, and both the phenotypic and genotypic levels are taken in account. The model is based on a long range cellular…

Statistical Mechanics · Physics 2007-05-23 Franco Bagnoli , Michele Bezzi

A formulation of bit-string models of language evolution, based on differential equations for the population speaking each language, is introduced and preliminarily studied. Connections with replicator dynamics and diffusion processes are…

Physics and Society · Physics 2009-11-13 Damian H. Zanette

Complex systems are often modeled as Boolean networks in attempts to capture their logical structure and reveal its dynamical consequences. Approximating the dynamics of continuous variables by discrete values and Boolean logic gates may,…

Molecular Networks · Quantitative Biology 2013-05-29 Johannes Norrell , Joshua E. S. Socolar

The goal of this paper is to provide mathematically rigorous tools for modelling the evolution of a community of interacting individuals. We model the population by a measure space where the measure determines the abundance of individual…

Probability · Mathematics 2017-05-17 Thomas Cass , Terry Lyons

Large multidimensionality of high-throughput datasets pertaining to cell signaling and gene regulation renders it difficult to extract mechanisms underlying the complex kinetics involving various biochemical compounds (e.g., proteins,…

Quantitative Methods · Quantitative Biology 2012-01-25 Michael Dworkin , Sayak Mukherjee , Ciriyam Jayaprakash , Jayajit Das

We analyze a stylized model of co-evolution between any two purely competing species (e.g., host and parasite), both sexually reproducing. Similarly to a recent model of Livnat \etal~\cite{evolfocs14} the fitness of an individual depends on…

Computer Science and Game Theory · Computer Science 2017-11-21 Georgios Piliouras , Leonard J. Schulman

Many networks are complex dynamical systems, where both attributes of nodes and topology of the network (link structure) can change with time. We propose a model of co-evolving networks where both node at- tributes and network structure…

Social and Information Networks · Computer Science 2011-06-15 Yoon-Sik Cho , Greg Ver Steeg , Aram Galstyan

The model of interaction between learning and evolutionary optimization is designed and investigated. The evolving population of modeled organisms is considered. The mechanism of the genetic assimilation of the acquired features during a…

Neural and Evolutionary Computing · Computer Science 2014-11-20 Vladimir G. Red'ko

We introduce a mathematical model of symbiosis between different species by taking into account the influence of each species on the carrying capacities of the others. The modeled entities can pertain to biological and ecological societies…

Biological Physics · Physics 2012-06-06 V. I. Yukalov , E. P. Yukalova , D. Sornette

The movement of organisms is subject to a multitude of influences of widely varying character: from the bio-mechanics of the individual, over the interaction with the complex environment many animals live in, to evolutionary pressure and…

Biological Physics · Physics 2013-07-18 Friedrich Lenz , Aleksei V. Chechkin , Rainer Klages

Interacting biological systems at all organizational levels display emergent behavior. Modeling these systems is made challenging by the number and variety of biological components and interactions (from molecules in gene regulatory…

Molecular Networks · Quantitative Biology 2023-10-20 Jordan C. Rozum , Colin Campbell , Eli Newby , Fatemeh Sadat Fatemi Nasrollahi , Reka Albert

A primary motivation for our research in Digital Ecosystems is the desire to exploit the self-organising properties of biological ecosystems. Ecosystems are thought to be robust, scalable architectures that can automatically solve complex,…

Neural and Evolutionary Computing · Computer Science 2016-11-18 G. Briscoe , S. Sadedin , G. Paperin

We propose a model of multispecies populations surviving on distributed resources. System dynamics are investigated under changes in abiotic factors such as the climate, as parameterized through environmental temperature. In particular, we…

Populations and Evolution · Quantitative Biology 2017-10-25 I. Sudakov , S. A. Vakulenko , D. Kirievskaya , K. M. Golden

The interplay between space and evolution is an important issue in population dynamics, that is in particular crucial in the emergence of polymorphism and spatial patterns. Recently, biological studies suggest that invasion and evolution…

Probability · Mathematics 2016-08-16 Nicolas Champagnat , Sylvie Méléard

Genetic interaction can be defined as a deviation of the phenotypic quantitative effect of a double gene mutation from the effect predicted from single mutations using a simple (e.g., multiplicative or linear additive) statistical model.…

Molecular Networks · Quantitative Biology 2015-04-24 Laurence Calzone , Emmanuel Barillot , Andrei Zinovyev
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