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Deep learning has seen remarkable developments over the last years, many of them inspired by neuroscience. However, the main learning mechanism behind these advances - error backpropagation - appears to be at odds with neurobiology. Here,…

Neurons and Cognition · Quantitative Biology 2018-10-29 João Sacramento , Rui Ponte Costa , Yoshua Bengio , Walter Senn

A key challenge for AI is to build embodied systems that operate in dynamically changing environments. Such systems must adapt to changing task contexts and learn continuously. Although standard deep learning systems achieve state of the…

Neural and Evolutionary Computing · Computer Science 2022-04-26 Abhiram Iyer , Karan Grewal , Akash Velu , Lucas Oliveira Souza , Jeremy Forest , Subutai Ahmad

Deep learning has led to significant advances in artificial intelligence, in part, by adopting strategies motivated by neurophysiology. However, it is unclear whether deep learning could occur in the real brain. Here, we show that a deep…

Neurons and Cognition · Quantitative Biology 2017-04-11 Jordan Guergiuev , Timothy P. Lillicrap , Blake A. Richards

This paper introduces a rate-based nonlinear neural network in which excitatory (E) neurons receive feedforward excitation from sensory (S) neurons, and inhibit each other through disynaptic pathways mediated by inhibitory (I) interneurons.…

Neurons and Cognition · Quantitative Biology 2019-01-01 H. Sebastian Seung

This paper presents a spike-based model which employs neurons with functionally distinct dendritic compartments for classifying high dimensional binary patterns. The synaptic inputs arriving on each dendritic subunit are nonlinearly…

Neural and Evolutionary Computing · Computer Science 2014-11-26 Shaista Hussain , Shih-Chii Liu , Arindam Basu

Inhibition is considered to shape neural activity, and broaden its pattern repertoire. In the sensory organs, where the anatomy of neural circuits is highly structured, lateral inhibition sharpens contrast among stimulus properties. The…

Neurons and Cognition · Quantitative Biology 2018-09-18 Netta Haroush , Shimon Marom

We present a method for adversarial attack detection based on the inspection of a sparse set of neurons. We follow the hypothesis that adversarial attacks introduce imperceptible perturbations in the input and that these perturbations…

Computer Vision and Pattern Recognition · Computer Science 2020-11-02 Roger Granda , Tinne Tuytelaars , Jose Oramas

Our understanding of biological neuronal networks has profoundly influenced the development of artificial neural networks (ANNs). However, neurons utilized in ANNs differ considerably from their biological counterparts, primarily due to the…

Neural and Evolutionary Computing · Computer Science 2025-04-09 Xundong Wu , Pengfei Zhao , Zilin Yu , Lei Ma , Ka-Wa Yip , Huajin Tang , Gang Pan , Poirazi Panayiota , Tiejun Huang

How neurons process their inputs crucially determines the dynamics of biological and artificial neural networks. In such neural and neural-like systems, synaptic input is typically considered to be merely transmitted linearly or sublinearly…

Biological Physics · Physics 2017-06-01 David Breuer , Marc Timme , Raoul-Martin Memmesheimer

How neurons integrate the myriad synaptic inputs scattered across their dendrites is a fundamental question in neuroscience. Multiple neurophysiological experiments have shown that dendritic non-linearities can have a strong influence on…

Neurons and Cognition · Quantitative Biology 2025-01-13 Clarissa Lauditi , Enrico M. Malatesta , Fabrizio Pittorino , Carlo Baldassi , Nicolas Brunel , Riccardo Zecchina

Deep neural networks are vulnerable to adversarial attacks, which can fool them by adding minuscule perturbations to the input images. The robustness of existing defenses suffers greatly under white-box attack settings, where an adversary…

Computer Vision and Pattern Recognition · Computer Science 2019-07-30 Aamir Mustafa , Salman Khan , Munawar Hayat , Roland Goecke , Jianbing Shen , Ling Shao

We propose a detector of adversarial samples that is based on the view of neural networks as discrete dynamic systems. The detector tells clean inputs from abnormal ones by comparing the discrete vector fields they follow through the…

Machine Learning · Computer Science 2023-06-09 Skander Karkar , Patrick Gallinari , Alain Rakotomamonjy

Deep Neural Networks (DNNs) are vulnerable to adversarial attacks: carefully constructed perturbations to an image can seriously impair classification accuracy, while being imperceptible to humans. While there has been a significant amount…

Machine Learning · Computer Science 2020-12-23 Can Bakiskan , Metehan Cekic , Ahmet Dundar Sezer , Upamanyu Madhow

Machine learning algorithms can be fooled by small well-designed adversarial perturbations. This is reminiscent of cellular decision-making where ligands (called antagonists) prevent correct signalling, like in early immune recognition. We…

Biological Physics · Physics 2019-07-31 Thomas J. Rademaker , Emmanuel Bengio , Paul François

Recent experimental studies indicate that synaptic changes induced by neuronal activity are discrete jumps between a small number of stable states. Learning in systems with discrete synapses is known to be a computationally hard problem.…

Neurons and Cognition · Quantitative Biology 2009-11-13 Carlo Baldassi , Alfredo Braunstein , Nicolas Brunel , Riccardo Zecchina

To be effective, efficient, and diverse, deep learning models need to dynamically choose its architecture based on signals from a population of neurons. We hypothesize dynamic routing models can be improved with neural inhibition in those…

Machine Learning · Computer Science 2025-07-08 Will Y. Zou , Jennifer Y. Zhang

Deep neural networks are learning models having achieved state of the art performance in many fields like prediction, computer vision, language processing and so on. However, it has been shown that certain inputs exist which would not trick…

Machine Learning · Computer Science 2020-06-03 Jay N. Paranjape , Rahul Kumar Dubey , Vijendran V Gopalan

Cortical pyramidal neurons have a complex dendritic anatomy, whose function is an active research field. In particular, the segregation between its soma and the apical dendritic tree is believed to play an active role in processing…

Neurons and Cognition · Quantitative Biology 2021-07-13 Fabian Schubert , Claudius Gros

Models of cortical neuronal circuits commonly depend on inhibitory feedback to control gain, provide signal normalization, and to selectively amplify signals using winner-take-all (WTA) dynamics. Such models generally assume that excitatory…

Neurons and Cognition · Quantitative Biology 2018-01-16 Ueli Rutishauser , Jean-Jacques Slotine , Rodney J. Douglas

We show that discrete synaptic weights can be efficiently used for learning in large scale neural systems, and lead to unanticipated computational performance. We focus on the representative case of learning random patterns with binary…

Disordered Systems and Neural Networks · Physics 2015-09-21 Carlo Baldassi , Alessandro Ingrosso , Carlo Lucibello , Luca Saglietti , Riccardo Zecchina
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