Related papers: Response variability in balanced cortical networks
Neuroscientists have worked on the problem of estimating synaptic properties, such as connectivity and strength, from simultaneously recorded spike trains since the 1960s. Recent years have seen renewed interest in the problem, coinciding…
The dynamics of local cortical networks are irregular, but correlated. Dynamic excitatory--inhibitory balance is a plausible mechanism that generates such irregular activity, but it remains unclear how balance is achieved and maintained in…
We analyze the dynamics of two coupled identical populations of quadratic integrate-and-fire neurons, which represent the canonical model for class I neurons near the spiking threshold. The populations are heterogeneous; they include both…
Interspike intervals describe the output of neurons. Signal transmission in a neuronal network implies that the output of some neurons becomes the input of others. The output should reproduce the main features of the input to avoid a…
Neuronal activity arises from an interaction between ongoing firing generated spontaneously by neural circuits and responses driven by external stimuli. Using mean-field analysis, we ask how a neural network that intrinsically generates…
Generalized linear models are one of the most efficient paradigms for predicting the correlated stochastic activity of neuronal networks in response to external stimuli, with applications in many brain areas. However, when dealing with…
Many systems are modulated by unknown slow processes. This hinders analysis in highly non-linear systems, such as excitable systems. We show that for such systems, if the input matches the sparse `spiky' nature of the output, the spiking…
All higher order central nervous systems exhibit spontaneous neural activity, though the purpose and mechanistic origin of such activity remains poorly understood. We explore the ignition and spread of collective spontaneous…
Spike synchrony, which occurs in various cortical areas in response to specific perception, action and memory tasks, has sparked a long-standing debate on the nature of temporal organization in cortex. One prominent view is that this type…
The activity of an isolated and auto-connected neuron is studied using Hodgkin--Huxley and Integrate-and-Fire frameworks. Main ingredients of the modeling are the auto-stimulating autaptic current observed in experiments, with a spontaneous…
Pairs of neurons in brain networks often share much of the input they receive from other neurons. Due to essential non-linearities of neuronal dynamics, the consequences for the correlation of the output spike trains are not well understood…
Firing rate fluctuations in neural populations are observed experimentally over multiple time scales, in single neurons, across trials when elicited by stimuli, and across populations. In this work, we examine how firing rate fluctuations…
This paper studies a stochastic neural field model that is extended from our previous paper [14]. The neural field model consists of many heterogeneous local populations of neurons. Rigorous results on the stochastic stability are proved,…
Recurrent neural networks with balanced excitation and inhibition exhibit irregular asynchronous dynamics, which is fundamental for cortical computations. Classical balance mechanisms require strong external inputs to sustain finite firing…
Strongly coupled, recurrent, balanced network models have been successful in describing and predicting many phenomena observed in cortical neural recordings. However, most balanced network models use current-based synapse models in place of…
We address the questions of identifying pairs of interacting neurons from the observation of their spiking activity. The neuronal network is modeled by a system of interacting point processes with memory of variable length. The influence of…
Neurons display spontaneous spiking (in the absence of stimulus signals) as well as a characteristic response to time-dependent external stimuli. In a simple but important class of stochastic neuron models, the integrate-and-fire model with…
Using a stochastic generalization of the Hodgkin–Huxley model, we consider the influence of intrinsic channel noise on the synchronization between the spiking activity of the excitable membrane and an externally applied periodic…
We investigate a network of integrate-and-fire neurons characterized by a distribution of spiking frequencies. Upon increasing the coupling strength, the model exhibits a transition from an asynchronous regime to a nontrivial collective…
Dynamics and function of neuronal networks are determined by their synaptic connectivity. Current experimental methods to analyze synaptic network structure on the cellular level, however, cover only small fractions of functional neuronal…