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Optical neural networks (ONNs) have demonstrated record-breaking potential in high-performance neuromorphic computing due to their ultra-high execution speed and low energy consumption. However, current learning protocols fail to provide…

Emerging Technologies · Computer Science 2021-09-07 Jiaqi Gu , Chenghao Feng , Zheng Zhao , Zhoufeng Ying , Ray T. Chen , David Z. Pan

Having the potential for high speed, high throughput, and low energy cost, optical neural networks (ONNs) have emerged as a promising candidate for accelerating deep learning tasks. In conventional ONNs, light amplitudes are modulated at…

Systems and Control · Electrical Eng. & Systems 2023-12-18 Ruidi Qiu , Amro Eldebiky , Grace Li Zhang , Xunzhao Yin , Cheng Zhuo , Ulf Schlichtmann , Bing Li

Convolutional Neural Networks (CNNs) have shown to be powerful medical image segmentation models. In this study, we address some of the main unresolved issues regarding these models. Specifically, training of these models on small medical…

Computer Vision and Pattern Recognition · Computer Science 2022-12-06 Davood Karimi , Ali Gholipour

We study the dynamics of the structure of a formal neural network wherein the strengths of the synapses are governed by spike-timing-dependent plasticity (STDP). For properly chosen input signals, there exists a steady state with a residual…

Neurons and Cognition · Quantitative Biology 2015-05-18 Quansheng Ren , Kiran M. Kolwankar , Areejit Samal , Jürgen Jost

The Ordered Covering Problem (OCP) arises in the context of the Discretizable Molecular Distance Geometry Problem (DMDGP), where the ordering of pruning edges significantly impacts the performance of the SBBU algorithm for protein structure…

Data Structures and Algorithms · Computer Science 2025-12-04 Michael Souza , Júlio Araújo , John Kesley Costa , Carlile Lavor

Diabetic neuropathy is a disorder characterized by impaired nerve function and reduction of the number of epidermal nerve fibers per epidermal surface. Additionally, as neuropathy related nerve fiber loss and regrowth progresses over time,…

The optic nerve head represents the intraocular section of the optic nerve (ONH), which is prone to damage by intraocular pressure. The advent of optical coherence tomography (OCT) has enabled the evaluation of novel optic nerve head…

Our ability to control a whole network can be achieved via a small set of driver nodes. While the minimum number of driver nodes needed for control is fixed in a given network, there are multiple choices for the driver node set. A quantity…

Physics and Society · Physics 2025-04-15 Xiaoyao Yu , Yongqing Liang , Xiaomeng Wang , Tao Jia

The Degree Realization problem requires, given a sequence $d$ of $n$ positive integers, to decide whether there exists a graph whose degrees correspond to $d$, and to construct such a graph if it exists. A more challenging variant of the…

Discrete Mathematics · Computer Science 2025-10-28 Amotz Bar-Noy , Igor Kalinichev , David Peleg , Dror Rawitz

To develop a new method to quantify nonperfused retinal capillaries (NPCs) by using co-registered optical coherence tomography (OCT) and OCT angiography (OCTA), and to evaluate NPCs in eyes with age-related macular degeneration (AMD) and…

Quantitative Methods · Quantitative Biology 2024-11-11 Min Gao , Yukun Guo , Tristan T. Hormel , Jie Wang , Elizabeth White , Dong-Wouk Park , Thomas S. Hwang , Steven T. Bailey , Yali Jia

We propose a linear programming (LP) framework for steady-state diffusion and flux optimization on geometric networks. The state variable satisfies a discrete diffusion law on a weighted, oriented graph, where conductances are scaled by…

Optimization and Control · Mathematics 2025-11-06 Harbir Antil , Rainald Löhner , Felipe Pérez

Despite deep convolutional neural networks' great success in object classification, it suffers from severe generalization performance drop under occlusion due to the inconsistency between training and testing data. Because of the large…

Computer Vision and Pattern Recognition · Computer Science 2019-11-15 Mingqing Xiao , Adam Kortylewski , Ruihai Wu , Siyuan Qiao , Wei Shen , Alan Yuille

We study a mathematical model of biological neuronal networks composed by any finite number $N \geq 2$ of non necessarily identical cells. The model is a deterministic dynamical system governed by finite-dimensional impulsive differential…

Biological Physics · Physics 2013-11-19 Eleonora Catsigeras

The design of neural hardware is informed by the prominence of differentiated processing and information integration in cognitive systems. The central role of communication leads to the principal assumption of the hardware platform: signals…

Neural and Evolutionary Computing · Computer Science 2018-05-28 Jeffrey M. Shainline , Sonia M. Buckley , Adam N. McCaughan , Jeff Chiles , Richard P. Mirin , Sae Woo Nam

We present a method for segmenting neuron membranes in 2D electron microscopy imagery. This segmentation task has been a bottleneck to reconstruction efforts of the brain's synaptic circuits. One common problem is the misclassification of…

Computer Vision and Pattern Recognition · Computer Science 2020-02-05 Thanuja D. Ambegoda , Matthew Cook

To make sense of the world our brains must analyze high-dimensional datasets streamed by our sensory organs. Because such analysis begins with dimensionality reduction, modelling early sensory processing requires biologically plausible…

Neurons and Cognition · Quantitative Biology 2016-01-27 Cengiz Pehlevan , Dmitri B. Chklovskii

We present an exploration of the rich theoretical connections between several classes of regularized models, network flows, and recent results in submodular function theory. This work unifies key aspects of these problems under a common…

Machine Learning · Statistics 2013-12-09 Hoyt Koepke , Marina Meila

Out-of-distribution (OoD) detection and segmentation have attracted growing attention as concerns about AI security rise. Conventional OoD detection methods identify the existence of OoD objects but lack spatial localization, limiting their…

Computer Vision and Pattern Recognition · Computer Science 2025-08-15 Wenjie Zhao , Jia Li , Yunhui Guo

Cortical neurons whose activity is recorded in behavioral experiments has been classified into several types such as stimulus-related neurons, delay-period neurons, and reward-related neurons. Moreover, the population activity of neurons…

Neurons and Cognition · Quantitative Biology 2018-11-27 Takuma Tanaka

In this paper, we address the adversarial training of neural ODEs from a robust control perspective. This is an alternative to the classical training via empirical risk minimization, and it is widely used to enforce reliable outcomes for…

Optimization and Control · Mathematics 2024-04-02 Cristina Cipriani , Alessandro Scagliotti , Tobias Wöhrer
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