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Phylogenetic trees are leaf-labelled trees, where the leaves correspond to extant species (taxa), and the internal vertices represent ancestral species. The evolutionary history of a set of species can be explained by more than one…

Data Structures and Algorithms · Computer Science 2016-09-07 Asish Mukhopadhyay , Puspal Bhabak

Multimodal alignment constructs a joint latent vector space where modalities representing the same concept map to neighboring latent vectors. We formulate this as an inverse problem and show that, under certain conditions, paired data from…

Machine Learning · Computer Science 2025-06-10 Abhi Kamboj , Minh N. Do

Motivation: High-throughput experimental techniques have been producing more and more protein-protein interaction (PPI) data. PPI network alignment greatly benefits the understanding of evolutionary relationship among species, helps…

Data Structures and Algorithms · Computer Science 2016-04-13 Somaye Hashemifar , Qixing Huang , Jinbo XU

Accurate and timely cancer diagnosis from histopathological slides is vital for effective clinical decision-making. This paper introduces DepViT-CAD, a deployable AI system for multi-class cancer diagnosis in histopathology. At its core is…

Image and Video Processing · Electrical Eng. & Systems 2025-07-15 Ashkan Shakarami , Lorenzo Nicole , Rocco Cappellesso , Angelo Paolo Dei Tos , Stefano Ghidoni

High annotation costs are a substantial bottleneck in applying modern deep learning architectures to clinically relevant medical use cases, substantiating the need for novel algorithms to learn from unlabeled data. In this work, we propose…

Computer Vision and Pattern Recognition · Computer Science 2021-11-29 Aiham Taleb , Matthias Kirchler , Remo Monti , Christoph Lippert

Masked image modeling (MIM) with transformer backbones has recently been exploited as a powerful self-supervised pre-training technique. The existing MIM methods adopt the strategy to mask random patches of the image and reconstruct the…

Computer Vision and Pattern Recognition · Computer Science 2024-02-05 Zhaohu Xing , Lei Zhu , Lequan Yu , Zhiheng Xing , Liang Wan

Multimodal representation alignment is pivotal for large language models and robotics. Traditional methods are often hindered by cross-modal information discrepancies and data scarcity, leading to suboptimal alignment spaces that overlook…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Zeyu Chen , Jie Li , Kai Han

Histopathological imaging is vital for cancer research and clinical practice, with multiplexed Immunofluorescence (MxIF) and Hematoxylin and Eosin (H&E) providing complementary insights. However, aligning different stains at the cell level…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Jun Jiang , Raymond Moore , Brenna Novotny , Leo Liu , Zachary Fogarty , Ray Guo , Markovic Svetomir , Chen Wang

Navigating dense and dynamic environments poses a significant challenge for autonomous driving systems, owing to the intricate nature of multimodal interaction, wherein the actions of various traffic participants and the autonomous vehicle…

Robotics · Computer Science 2024-08-29 Tong Li , Lu Zhang , Sikang Liu , Shaojie Shen

While Unsupervised Domain Adaptation (UDA) algorithms, i.e., there are only labeled data from source domains, have been actively studied in recent years, most algorithms and theoretical results focus on Single-source Unsupervised Domain…

Machine Learning · Computer Science 2022-01-05 Yongchun Zhu , Fuzhen Zhuang , Deqing Wang

Molecular phylogenetic techniques do not generally account for such common evolutionary events as site insertions and deletions (known as indels). Instead tree building algorithms and ancestral state inference procedures typically rely on…

Probability · Mathematics 2011-09-07 Alexandr Andoni , Constantinos Daskalakis , Avinatan Hassidim , Sebastien Roch

To address the dual challenges of the curse of dimensionality and the difficulty in separating intra-cluster and inter-cluster structures in high-dimensional manifold embedding, we proposes an Adaptive Multi-Scale Manifold Embedding (AMSME)…

Machine Learning · Computer Science 2025-03-20 Tianhao Ni , Bingjie Li , Zhigang Yao

Multimodal alignment of histopathology encoders with transcriptomic and genomic data has been shown to significantly improve performance in downstream diagnostic tasks. Hematological cytology is unique in that visual single-cell evaluation…

Computer Vision and Pattern Recognition · Computer Science 2026-05-29 Muhammed Furkan Dasdelen , Fatih Ozlugedik , Ilaria Looser , Rao Muhammad Umer , Christian Pohlkamp , Carsten Marr

Recent advances in multi-instance learning (MIL) have witnessed impressive performance in whole slide image (WSI) analysis. However, the inherent sparsity of tumors and their morphological diversity lead to obvious heterogeneity across…

Image and Video Processing · Electrical Eng. & Systems 2026-02-25 Tingting Zheng , Hongxun Yao , Kui Jiang , Sicheng Zhao , Yi Xiao

In this article we provide a comprehensive review of the different evolutionary algorithm techniques used to address multimodal optimization problems, classifying them according to the nature of their approach. On the one hand there are…

Neural and Evolutionary Computing · Computer Science 2015-08-24 Noe Casas

New powerful tools for tackling life science problems have been created by recent advances in machine learning. The purpose of the paper is to discuss the potential advantages of gene recommendation performed by artificial intelligence…

Quantitative Methods · Quantitative Biology 2023-03-23 Daniele Brambilla , Davide Maria Giacomini , Luca Muscarnera , Andrea Mazzoleni

Alzheimer's disease (AD) is an incurable neurodegenerative condition leading to cognitive and functional deterioration. Given the lack of a cure, prompt and precise AD diagnosis is vital, a complex process dependent on multiple factors and…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Guangqian Yang , Kangrui Du , Zhihan Yang , Ye Du , Yongping Zheng , Shujun Wang

Legged robots are popular candidates for missions in challenging terrains due to the wide variety of locomotion strategies they can employ. Terrain classification is a key enabling technology for autonomous legged robots, as it allows the…

Robotics · Computer Science 2020-11-25 Ahmadreza Ahmadi , Tønnes Nygaard , Navinda Kottege , David Howard , Nicolas Hudson

A frame is a generalization of a basis of a vector space to a redundant overspanning set whose vectors are linearly dependent. Frames find applications in signal processing and quantum information theory. We present a genetic algorithm that…

Computational Physics · Physics 2025-08-13 Sebastián Roca-Jerat , Juan Román-Roche

Reliable models should not only predict correctly, but also justify decisions with acceptable evidence. Yet conventional supervised learning typically provides only class-level labels, allowing models to achieve high accuracy through…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Ruoyu Chen , Shangquan Sun , Xiaoqing Guo , Sanyi Zhang , Kangwei Liu , Shiming Liu , Zhangcheng Wang , Qunli Zhang , Hua Zhang , Xiaochun Cao