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Neural systems are comprised of interacting units, and relevant information regarding their function or malfunction can be inferred by analyzing the statistical dependencies between the activity of each unit. Whilst correlations and mutual…
Neural network oscillations are a fundamental mechanism for cognition, perception and consciousness. Consequently, perturbations of network activity play an important role in the pathophysiology of brain disorders. When structural…
Seizure onset detection in electroencephalography (EEG) signals is a challenging task due to the non-stereotyped seizure activities as well as their stochastic and non-stationary characteristics in nature. Joint spectral-temporal features…
A seizure's electrographic dynamics are characterised by its spatiotemporal evolution, also termed dynamical "pathway" and the time it takes to complete that pathway, which results in the seizure's duration. Both seizure pathways and…
In clinical neuroscience, epileptic seizures have been associated with the sudden emergence of coupled activity across the brain. The resulting functional networks - in which edges indicate strong enough coupling between brain regions - are…
Complex spatial connectivity patterns, such as interictal suppression and ictal propagation, complicate accurate drug-resistant epilepsy (DRE) seizure detection using stereotactic electroencephalography (SEEG) and traditional machine…
Epileptic seizure detection and classification in clinical electroencephalogram data still is a challenge, and only low sensitivity with a high rate of false positives has been achieved with commercially available seizure detection tools,…
Epilepsy is a chronic neurological disorder affecting more than 50 million people globally. An epileptic seizure acts like a temporary shock to the neuronal system, disrupting normal electrical activity in the brain. Epilepsy is frequently…
In this study, we present a criterion based on the analysis of EEG signals through the mean of the conventional power spectral density (PSD) in the aim to localize and detect the epileptic area of the brain. Firstly, as the EEG signals are…
Seizures are one of the defining symptoms in patients with epilepsy, and due to their unannounced occurrence, they can pose a severe risk for the individual that suffers it. New research efforts are showing a promising future for the…
Seizure activity is a ubiquitous and pernicious pathophysiology that, in principle, should yield to mathematical treatments of (neuronal) ensemble dynamics - and therefore interventions on stochastic chaos. A seizure can be characterised as…
Over the last years, increasing evidence has fuelled the hypothesis that Autism Spectrum Disorder (ASD) is a condition of altered brain functional connectivity. The great majority of these empirical studies rely on functional magnetic…
We investigate several quantifiers of the electroencephalogram (EEG) signal with respect to their ability to indicate depth of anesthesia. For 17 patients anesthetized with Sevoflurane, three established measures (two spectral and one based…
Accurate prediction of epileptic seizures has remained elusive, despite the many advances in machine learning and time-series classification. In this work, we develop a convolutional network module that exploits Electroencephalogram (EEG)…
Diagnosing epilepsy requires accurate seizure detection and classification, but traditional manual EEG signal analysis is resource-intensive. Meanwhile, automated algorithms often overlook EEG's geometric and semantic properties critical…
Cortical activity recorded through EEG and MEG reflects complex dynamics that span multiple temporal and spatial scales. Spectral analyses of these signals consistently reveal power-law behaviour, a hallmark of turbulent systems. In this…
Epilepsy is a chronic neurological disorder affecting more than 65 million people worldwide and manifested by recurrent unprovoked seizures. The unpredictability of seizures not only degrades the quality of life of the patients, but it can…
Insomnia affects a vast population of the world and can have a wide range of causes. Existing treatments for insomnia have been linked with many side effects like headaches, dizziness, etc. As such, there is a clear need for improved…
We investigate the nature of the modifications in the temporal dynamics manifested in the high-frequency EEG spectra of the normal human brain in comparison to the diseased brain undergoing epilepsy. For this purpose, the Fourier…
Pathophysiolpgical modelling of brain systems from microscale to macroscale remains difficult in group comparisons partly because of the infeasibility of modelling the interactions of thousands of neurons at the scales involved. Here, to…