Related papers: An Explicit Space-time Adaptive Method for Simulat…
Existing digital human models approximate the human skeletal system using rigid bodies connected by rotational joints. While the simplification is considered acceptable for legs and arms, it significantly lacks fidelity to model rich torso…
The growing importance of real-time simulation in the medical field has exposed the limitations and bottlenecks inherent in the digital representation of complex biological systems. This paper presents a novel methodology aimed at advancing…
In numerical simulations of cardiac mechanics, coupling the heart to a model of the circulatory system is essential for capturing physiological cardiac behavior. A popular and efficient technique is to use an electrical circuit analogy,…
Employing simplex space-time meshes enlarges the scope of compressible flow simulations. The simultaneous discretization of space and time with simplex elements extends the flexibility of unstructured meshes from space to time. In this…
We provide a road towards obtaining gravitational waveforms from inspiraling material binaries with an accuracy viable for third-generation gravitational wave detectors, without necessarily advancing computational hardware or…
Cardiac parametric mapping is useful for evaluating cardiac fibrosis and edema. Parametric mapping relies on single-shot heartbeat-by-heartbeat imaging, which is susceptible to intra-shot motion during the imaging window. However, reducing…
Cardiac magnetic resonance imaging (MRI) requires reconstructing a real-time video of a beating heart from continuous highly under-sampled measurements. This task is challenging since the object to be reconstructed (the heart) is…
Engineered heart tissues (EHTs) present a potential solution to some of the current challenges in the treatment of heart disease; however, the development of mature, adult-like cardiac tissues remains elusive. Mechanical stimuli have been…
We present a novel approach aimed at high-performance uncertainty quantification for time-dependent problems governed by partial differential equations. In particular, we consider input uncertainties described by a Karhunen-Loeeve expansion…
Numerical radiation-hydrodynamics (RHD) for non-relativistic flows is a challenging problem because it encompasses processes acting over a very broad range of timescales, and where the relative importance of these processes often varies by…
We present a probabilistic framework for modeling structured spatiotemporal dynamics from sparse observations, focusing on cardiac motion. Our approach integrates neural ordinary differential equations (NODEs), graph neural networks (GNNs),…
There is a broad need in the neuroscience community to understand and visualize large-scale recordings of neural activity, big data acquired by tens or hundreds of electrodes simultaneously recording dynamic brain activity over minutes to…
We present a novel approach to investigate the long-time stochastic dynamics of multi-dimensional classical systems, in contact with a heat-bath. When the potential energy landscape is rugged, the kinetics displays a decoupling of short and…
We present an efficient quantum algorithm for simulating the dynamics of Markovian open quantum systems. The performance of our algorithm is similar to the previous state-of-the-art quantum algorithm, i.e., it scales linearly in evolution…
It is generally assumed that all cells in models of the electrical behavior of cardiac tissue have the same properties. However, there are differences in cardiac cells that are not well characterized but cause spatial heterogeneity of the…
Data movement is becoming the dominant contributor to the time and energy costs of computation across a wide range of application domains. However, time complexity is inadequate to analyze data movement. This work expands upon Data Movement…
Purpose: To develop a cardiac T1 mapping method for free-breathing 3D T1 mapping of the whole heart at 3T with transmit B1 (B1+) correction Methods: A free-breathing, ECG-gated inversion recovery sequence with spoiled gradient-echo readout…
Efficient and faithful parallel simulation of large asynchronous systems is a challenging computational problem. It requires using the concept of local simulated times and a synchronization scheme. We study the scalability of massively…
Characterising the representation of sensory stimuli in the brain is a fundamental scientific endeavor, which can illuminate principles of information coding. Most characterizations reduce the dimensionality of neural data by converting…
The time domain analysis of eddy current problems often requires the simulation of long time intervals, e.g. until a steady state is reached. Fast-switching excitations e.g. in pulsedwidth modulated signals require in addition very small…