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In this work, we integrate theoretical modeling, molecular simulation, and empirical analysis to identify and characterize evolutionary hysteresis. We first show how epistatic interactions create bistable fitness landscapes and structural…

Populations and Evolution · Quantitative Biology 2025-12-23 Luke Piszkin , Dervis Can Vural

We investigate the properties of a deterministic walk, whose locomotion rule is always to travel to the nearest site. Initially the sites are randomly distributed in a closed rectangular ($A/L \times L)$ landscape and, once reached, they…

Disordered Systems and Neural Networks · Physics 2009-11-13 M. C. Santos , D. Boyer , O. Miramontes , G. M. Viswanathan , E. P. Raposo , J. L. Mateos , M. G. E. da Luz

This thesis examines linearly edge-reinforced random walks on infinite trees. In particular, recurrence and transience of such random walks on general (fixed) trees as well as on Galton-Watson trees (i.e. random trees) is characterized, and…

Probability · Mathematics 2023-09-01 Fabian Michel

Due to stochastic fluctuations arising from finite population size, known as genetic drift, the ability of a population to explore a rugged fitness landscape depends on its size. In the weak mutation regime, while the mean steady-state…

Populations and Evolution · Quantitative Biology 2024-12-30 Richard Servajean , Anne-Florence Bitbol

We propose a model of a one-dimensional random walk in dynamic random environment that interpolates between two classical settings: (I) the random environment is sampled at time zero only; (II) the random environment is resampled at every…

Probability · Mathematics 2017-08-07 L. Avena , F. den Hollander

This study focuses on open quasispecies systems with competition and death flow, described by modified Eigen and Crow-Kimura models. We examine the evolutionary adaptation process as a reaction to changes in rates. One of the fundamental…

Populations and Evolution · Quantitative Biology 2021-12-01 Igor Samokhin , Tatiana Yakushkina , Dmitry Markin , Alexander S. Bratus

We study the adaptation dynamics of a maladapted asexual population on rugged fitness landscapes with many local fitness peaks. The distribution of beneficial fitness effects is assumed to belong to one of the three extreme value domains,…

Populations and Evolution · Quantitative Biology 2016-01-13 Sarada Seetharaman , Kavita Jain

Evolution depends on the possibility of successfully exploring fitness landscapes via mutation and recombination. With these search procedures, exploration is difficult in "rugged" fitness landscapes, where small mutations can drastically…

Adaptation and Self-Organizing Systems · Physics 2016-09-08 Carlos Gershenson , Stuart A. Kauffman , Ilya Shmulevich

Virtually all real-world networks are dynamical entities. In social networks, the propensity of nodes to engage in social interactions (activity) and their chances to be selected by active nodes (attractiveness) are heterogeneously…

Physics and Society · Physics 2017-06-13 Laura Alessandretti , Kaiyuan Sun , Andrea Baronchelli , Nicola Perra

Exploiting the coherent medium approximation, random walk among sites distributed randomly in space is investigated when the jump rate depends on the distance between two adjacent sites. In one dimension, it is shown that when the jump rate…

Statistical Mechanics · Physics 2021-09-27 Takashi Odagaki

The random walk process in a nonhomogeneous medium, characterised by a L\'evy stable distribution of jump length, is discussed. The width depends on a position: either before the jump or after that. In the latter case, the density slope is…

Statistical Mechanics · Physics 2017-03-29 Tomasz Srokowski

We analyze a variant of the Noisy $K$-Branching Random Walk, a population model that evolves according to the following procedure. At each time step, each individual produces a large number of offspring that inherit the fitness of their…

Probability · Mathematics 2025-10-01 Colin Desmarais , Emmanuel Schertzer , Zsófia Talyigás

How fast does a population evolve from one fitness peak to another? We study the dynamics of evolving, asexually reproducing populations in which a certain number of mutations jointly confer a fitness advantage. We consider the time until a…

Populations and Evolution · Quantitative Biology 2010-03-31 Chaitanya S. Gokhale , Yoh Iwasa , Martin A. Nowak , Arne Traulsen

Adaptation of asexual populations is driven by beneficial mutations and therefore the dynamics of this process, besides other factors, depend on the distribution of beneficial fitness effects. It is known that on uncorrelated fitness…

Populations and Evolution · Quantitative Biology 2016-08-05 Sona John , Sarada Seetharaman

Macroevolution is considered as a problem of stochastic dynamics in a system with many competing agents. Evolutionary events (speciations and extinctions) are triggered by fitness records found by random exploration of the agents' fitness…

adap-org · Physics 2017-01-11 Paolo Sibani , Michael Brandt , Preben Alstroem

One essential ingredient of evolutionary theory is the concept of fitness as a measure for a species' success in its living conditions. Here, we quantify the effect of environmental fluctuations onto fitness by analytical calculations on a…

Populations and Evolution · Quantitative Biology 2015-05-19 Anna Melbinger , Massimo Vergassola

We investigate the dynamics of random walks on weighted networks. Assuming that the edge's weight and the node's strength are used as local information by a random walker, we study two kinds of walks, weight-dependent walk and…

Statistical Mechanics · Physics 2015-06-25 An-Cai Wu , Xin-Jian Xu , Zhi-Xi Wu , Ying-Hai Wang

Genotypic fitness landscapes are constructed by assessing the fitness of all possible combinations of a given number of mutations. In the last years, several experimental fitness landscapes have been completely resolved. As fitness…

Populations and Evolution · Quantitative Biology 2015-07-02 Luca Ferretti , Daniel Weinreich , Benjamin Schmiegelt , Atsushi Yamauchi , Yutaka Kobayashi , Fumio Tajima , Guillaume Achaz

In a co-evolutionary context, the survive probability of individual elements of a system depends on their relation with their neighbors. The natural selection process depends on the whole population, which is determined by local events…

Biological Physics · Physics 2009-11-13 Juan G. Diaz Ochoa

Random walks find applications in many areas of science and are the heart of essential network analytic tools. When defined on temporal networks, even basic random walk models may exhibit a rich spectrum of behaviours, due to the…

Physics and Society · Physics 2019-11-11 Julien Petit , Renaud Lambiotte , Timoteo Carletti
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