Related papers: Note on the dynamic instability of microtubules
Microtubules are stiff filamentary proteins that constitute an important component of the cytoskeleton of cells. These are known to exhibit a dynamic instability. A steadily growing microtubule can suddenly start depolymerizing very…
Starting from the hypothesis that the tubulin dimer is a conformationally bistable molecule - fluctuating between a curved and a straight configuration at room temperature - we develop a model for polymorphic dynamics of the microtubule…
A simple stochastic model which describes microtubule dynamics and explicitly takes into account the relevant biochemical processes is presented. The model incorporates binding and unbinding of monomers and random phosphate release inside…
This paper provides the phase transition analysis of a reaction diffusion equations system modeling dynamic instability of microtubules. For this purpose we have generalized the macroscopic model studied by Mour\~ao et all [MSS]. This model…
Dynamic instability of microtubules is considered using frameworks of non-linear thermodynamics and non-equilibrium reaction-diffusion systems. Stochastic assembly/disassembly phases in the polymerization dynamics of microtubules are…
We describe the dynamics of a stream of equally spaced macroscopic particles in orbit around a central body (e.g. a planet or star). A co-orbital configuration of small bodies may be subject to gravitational instability, which takes the…
Microtubule dynamic instability arises from the hydrolysis of GTP bound to the beta-monomer of the tubulin dimer. The conformational change induced by hydrolysis is unknown, but microtubules disassemble into protofilaments of GDP-bound…
Microtubules have been in biophysical focus for several decades. Yet the confusing and mutually contradicting results regarding their elasticity and fluctuations have shed some doubts on their present understanding. In this paper we expose…
We study the bendocapillary instability of a liquid droplet that part fills a flexible walled channel. Inspired by experiments in which a `weaving' pattern emerges as droplets of liquid are condensed slowly into deformable microchannels, we…
A novel theoretical model of dynamic instability of a system of linear (1D) microtubules (MTs) in a bounded domain is introduced for studying the role of a cell edge in vivo and analyzing the effect of competition for a limited amount of…
Microtubule dynamic instability allows search and capture of kinetochores during spindle formation, an important process for accurate chromosome segregation during cell division. Recent work has found that microtubule rotational diffusion…
The stability of a rotating fluid disk to the formation of spiral arms is studied in the tightwinding approximation in the linear regime. The dispersion relation for spirals that was derived by Bertin et al. is shown to contain a new,…
We discovered an oscillatory instability in a system of inelastically colliding hard spheres, driven by two opposite "thermal" walls at zero gravity. The instability, predicted by a linear stability analysis of the equations of granular…
We develop an effective model to describe the dynamics of a system of particle moving in circular configurations around a central mass, by considering the continuum limit of the angular distribution, to obtain the stable configurations for…
We describe the approximation of a continuous dynamical system on a p. l. manifold or Cantor set by a tractable system. A system is tractable when it has a finite number of chain components and, with respect to a given full background…
One interesting class of gravitational radiation sources includes rapidly rotating astrophysical objects that encounter dynamical instabilities. We have carried out a set of simulations of rotationally induced instabilities in…
We propose a stochastic model that accounts for the growth, catastrophe and rescue processes of steady state microtubules assembled from MAP-free tubulin. Both experimentally and theoretically we study the perturbation of microtubule…
The intermittent transition between slow growth and rapid shrinkage in polymeric assemblies is termed dynamic instability, a feature observed in a variety of biochemically distinct assemblies including microtubules, actin and their…
A sequence of large invertible matrices given by a small random perturbation around a fixed diagonal and positive matrix induces a random dynamics on a high-dimensional sphere. For a certain class of rotationally invariant random…
The instability of a Fermi-liquid drop with respect to bulk density distortions is considered. It is shown that the presence of the surface strongly reduces the growth rate of the bulk instability of the finite Fermi-liquid drop because of…