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The increase of existing computational capabilities has made simulation emerge as a third discipline of Science, lying midway between experimental and purely theoretical branches [1, 2]. Simulation enables the evaluation of quantities which…

Computational Physics · Physics 2015-06-05 Pablo García-Risueño , Pablo E. Ibáñez

Vertex models represent confluent tissue by polygonal or polyhedral tilings of space, with the individual cell interacting via force laws that depend on both the geometry of the cells and the topology of the tessellation. This dependence on…

Biological Physics · Physics 2017-09-13 Daniel M. Sussman

A low-power precision-scalable processor for ConvNets or convolutional neural networks (CNN) is implemented in a 40nm technology. Its 256 parallel processing units achieve a peak 102GOPS running at 204MHz. To minimize energy consumption…

Hardware Architecture · Computer Science 2016-06-17 Bert Moons , Marian Verhelst

Using a realistic molecular catalyst system, we conduct scaling studies of ab initio molecular dynamics simulations using the CP2K code on both Intel Xeon CPU and NVIDIA V100 GPU architectures. We explore using process placement and…

Performance · Computer Science 2021-09-13 Dewi Yokelson , Nikolay V. Tkachenko , Robert Robey , Ying Wai Li , Pavel A. Dub

A previous study of MD algorithms designed for GPU use is extended to cover more recent developments in GPU architecture. Algorithm modifications are described, together with extensions to more complex systems. New measurements include the…

Computational Physics · Physics 2022-04-13 D C Rapaport

We present a GPU implementation of LAMMPS, a widely-used parallel molecular dynamics (MD) software package, and show 5x to 13x single node speedups versus the CPU-only version of LAMMPS. This new CUDA package for LAMMPS also enables…

Materials Science · Physics 2011-03-08 Christian R. Trott , Lars Winterfeld , Paul S. Crozier

Power awareness is fast becoming immensely important in computing, ranging from the traditional High Performance Computing applications, to the new generation of data centric workloads. In this work we describe our efforts towards a power…

Mathematical Software · Computer Science 2014-05-20 Pavel Klavík , A. Cristiano I. Malossi , Constantin Bekas , Alessandro Curioni

In this paper, we describe the architecture and performance of the GRAPE-6 system, a massively-parallel special-purpose computer for astrophysical $N$-body simulations. GRAPE-6 is the successor of GRAPE-4, which was completed in 1995 and…

Astrophysics · Physics 2015-06-24 Junichiro Makino , Toshiyuki Fukushige , Masaki Koga , Ken Namura

Molecular dynamics (MD) simulations have transformed our understanding of the nanoscale, driving breakthroughs in materials science, computational chemistry, and several other fields, including biophysics and drug design. Even on exascale…

Recently, special-purpose computers have surpassed general-purpose computers in the speed with which large-scale stellar dynamics simulations can be performed. Speeds up to a Teraflops are now available, for simulations in a variety of…

Astrophysics · Physics 2007-05-23 Piet Hut

Supercomputers become faster as hardware and software technologies continue to evolve. Current supercomputers are capable of 1015 floating point operations per second (FLOPS) that called Petascale system. The High Performance Computer (HPC)…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-09-27 Jalal Abdulbaqi

Current computers operate at enormous speeds of ~10^13 bits/s, but their principle of sequential logic operation has remained unchanged since the 1950s. Though our brain is much slower on a per-neuron base (~10^3 firings/s), it is capable…

Emerging Technologies · Computer Science 2015-05-30 Anirban Bandyopadhyay , Ranjit Pati , Satyajit Sahu , Ferdinand Peper , Daisuke Fujita

Due to their highly parallel multi-cores architecture, GPUs are being increasingly used in a wide range of computationally intensive applications. Compared to CPUs, GPUs can achieve higher performances at accelerating the programs'…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-10-05 Frédéric Magoulès , Abal-Kassim Cheik Ahamed , Alban Desmaison , Jean-Christophe Léchenet , François Mayer , Haifa Ben Salem , Thomas Zhu

This paper explores the potential of cryogenic semiconductor computing and superconductor electronics as promising alternatives to traditional semiconductor devices. As semiconductor devices face challenges such as increased leakage…

Hardware Architecture · Computer Science 2024-09-09 Kunal Pai , Anusheel Nand , Jason Lowe-Power

Classical molecular dynamics (MD) simulations are important tools in life and material sciences since they allow studying chemical and biological processes in detail. However, the inherent scalability problem of particle-particle…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-08-14 Michael Schaffner , Luca Benini

Living cells use readout molecules to record the state of receptor proteins, similar to measurements or copies in typical computational devices. But is this analogy rigorous? Can cells be optimally efficient, and if not, why? We show that,…

Molecular Networks · Quantitative Biology 2017-04-12 Thomas E. Ouldridge , Christopher C. Govern , Pieter Rein ten Wolde

On modern architectures, the performance of 32-bit operations is often at least twice as fast as the performance of 64-bit operations. By using a combination of 32-bit and 64-bit floating point arithmetic, the performance of many dense and…

Mathematical Software · Computer Science 2015-05-13 Marc Baboulin , Alfredo Buttari , Jack Dongarra , Jakub Kurzak , Julie Langou , Julien Langou , Piotr Luszczek , Stanimire Tomov

The Intel Haswell-EP processor generation introduces several major advancements of power control and energy-efficiency features. For computationally intense applications using advanced vector extension (AVX) instructions, the processor…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-08-27 Joseph Schuchart , Daniel Hackenberg , Robert Schöne , Thomas Ilsche , Ramkumar Nagappan , Michael K. Patterson

The output of a 200 kHz, 34 W, 300 fs Yb amplifier is compressed to 31 fs with > 88 % efficiency to reach a peak power of 2.5 GW, which to date is a record for a single-stage bulk multi-pass cell. Despite operation 80 times above the…

We present the GPU version of DeePMD-kit, which, upon training a deep neural network model using ab initio data, can drive extremely large-scale molecular dynamics (MD) simulation with ab initio accuracy. Our tests show that the GPU version…

Computational Physics · Physics 2020-10-28 Denghui Lu , Han Wang , Mohan Chen , Jiduan Liu , Lin Lin , Roberto Car , Weinan E , Weile Jia , Linfeng Zhang