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Heart rate variability studies depend on the robust calculation of the tachogram, the heart rate times series, usually by the detection of R peaks in the electrocardiogram (ECG). ECGs however are subject to a number of sources of noise…

Quantitative Methods · Quantitative Biology 2019-02-19 Sean Parsons , Jan Huizinga

The oscillations of the human heart rate are inherently complex and non-linear -- they are best described by mathematical chaos, and they present a challenge when applied to the practical domain of cardiovascular health monitoring in…

Machine Learning · Computer Science 2025-11-03 Berken Utku Demirel , Christian Holz

In this paper, we are interested in testing if the volatility process is constant or not during a given time span by using high-frequency data with the presence of jumps and microstructure noise. Based on estimators of integrated volatility…

Econometrics · Economics 2020-10-16 Qiang Liu , Zhi Liu , Chuanhai Zhang

Factor structure of heart rate periodogram has been detected with factor analysis. The results showed that there are at least four periodical phenomena of HRV. Two of them have not been discovered and physiologically explained yet. Their…

Tissues and Organs · Quantitative Biology 2010-05-07 V. Mukhin

This paper presents a central limit theorem for a pre-averaged version of the realized covariance estimator for the quadratic covariation of a discretely observed semimartingale with noise. The semimartingale possibly has jumps, while the…

Statistics Theory · Mathematics 2016-03-31 Yuta Koike

We report unexpected evidence of critical fluctuations of the electric potential of the heart during atrial fibrillation in humans. Scale invariance and long range correlations are found, which we show cannot be accounted for solely with…

Tissues and Organs · Quantitative Biology 2016-04-27 G. Attuel , N. Derval , T. Desplantez , M. Haissaguerre , M. Hocini , P. Jaïs , R. Dubois

Ordinary differential equation models are used to describe dynamic processes across biology. To perform likelihood-based parameter inference on these models, it is necessary to specify a statistical process representing the contribution of…

Whilst there are a plethora of algorithms for detecting changes in mean in univariate time-series, almost all struggle in real applications where there is autocorrelated noise or where the mean fluctuates locally between the abrupt changes…

Methodology · Statistics 2021-10-18 Gaetano Romano , Guillem Rigaill , Vincent Runge , Paul Fearnhead

Atrial Fibrillation (AF) is among one of the most common types of heart arrhythmia afflicting more than 3 million people in the U.S. alone. AF is estimated to be the cause of death of 1 in 4 individuals. Recent advancements in Artificial…

Signal Processing · Electrical Eng. & Systems 2020-11-03 James Belen , Sajad Mousavi , Alireza Shamsoshoara , Fatemeh Afghah

Atrial fibrillation (AF) is the most common form of arrhythmia with accelerated and irregular heart rate (HR), leading to both heart failure and stroke and being responsible for an increase in cardiovascular morbidity and mortality. In…

Fluid Dynamics · Physics 2018-06-26 Stefania Scarsoglio , Caterina Gallo , Luca Ridolfi

Background. Different mechanisms have been proposed to relate atrial fibrillation (AF) and coronary flow impairment, even in absence of relevant coronary artery disease (CAD). However, the underlying hemodynamics remains unclear. Aim of the…

Medical Physics · Physics 2019-04-17 Stefania Scarsoglio , Caterina Gallo , Andrea Saglietto , Luca Ridolfi , Matteo Anselmino

The instability of an atomic clock is characterized by the Allan variance, a measure widely used to describe the noise of frequency standards. We provide an explicit method to find the ultimate bound on the Allan variance of an atomic clock…

Quantum Physics · Physics 2016-08-30 Krzysztof Chabuda , Ian Leroux , Rafal Demkowicz-Dobrzanski

The knowledge of transitions between regular, laminar or chaotic behavior is essential to understand the underlying mechanisms behind complex systems. While several linear approaches are often insufficient to describe such processes, there…

Medical Physics · Physics 2007-05-23 N. Marwan , N. Wessel , U. Meyerfeldt , A. Schirdewan , J. Kurths

In this article, the dynamics and complexity of a noise induced blood flow system have been investigated. Changes in the dynamics have been recognized by measuring the periodicity over significant parameters. Chaotic as well as non-chaotic…

Adaptation and Self-Organizing Systems · Physics 2020-01-08 Bo Yan , Sayan Mukherjee , Shaobo He

Slow fluctuations of a qubit frequency are one of the major problems faced by quantum computers. To understand their origin it is necessary to go beyond the analysis of their spectra. We show that characteristic features of the fluctuations…

Quantum Physics · Physics 2024-01-11 Filip Wudarski , Yaxing Zhang , M. I. Dykman

A noise source model, consisting of a pulse sequence at random times with memory, is presented. By varying the memory we can obtain variable randomness of the stochastic process. The delay time between pulses, i. e. the noise memory,…

Statistical Mechanics · Physics 2009-09-29 O. Chichigina , D. Valenti , B. Spagnolo

Signals from heart transplant recipients can be considered to be a natural source of information for a better understanding of the impact of the autonomic nervous system on the complexity of heart rate variability. Beat-to-beat heart rate…

In this paper we address the question of robustness of critical bit rates for the stabilization of networked control systems over digital communication channels. For a deterministic nonlinear system, the smallest bit rate above which…

Optimization and Control · Mathematics 2016-10-25 Adriano Da Silva , Christoph Kawan

We analyze the frequency dependence of shot noise in a spin filter consisting of a normal grain and ferromagnetic electrodes separated by tunnel barriers. The source of frequency-dependent noise is random spin-flip electron scattering that…

Mesoscale and Nanoscale Physics · Physics 2009-11-11 K. E. Nagaev , L. I. Glazman

Variations of instantaneous heart rate appears regularly oscillatory in deeper levels of anesthesia and less regular in lighter levels of anesthesia. It is impossible to observe this "rhythmic-to-non-rhythmic" phenomenon from raw…

Neurons and Cognition · Quantitative Biology 2015-02-11 Yu-Ting Lin