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This paper explores the use of a soft ground-truth mask ("soft mask'') to train a Fully Convolutional Neural Network (FCNN) for segmentation of Multiple Sclerosis (MS) lesions. Detection and segmentation of MS lesions is a complex task…

Computer Vision and Pattern Recognition · Computer Science 2019-01-29 Eytan Kats , Jacob Goldberger , Hayit Greenspan

Objective: A method to predict the relationships between decompressed volume of orbital soft tissues, backward displacement of globe after osteotomy, and force exerted by the surgeon, was proposed to improve surgery planning in exophthalmia…

Medical Physics · Physics 2007-05-23 Vincent Luboz , Annaig Pedrono , Dominique Ambard , Franck Boutault , Yohan Payan , Pascal Swider

Detecting and classifying cells in histopathology H\&E stained whole-slide images is a core task in computational pathology, as it provides valuable insight into the tumor microenvironment. In this work we investigate the impact of ground…

Image and Video Processing · Electrical Eng. & Systems 2023-12-20 Lydia A. Schoenpflug , Viktor H. Koelzer

Hard-magnetic soft materials (HMSMs) are particulate composites that consist of a soft matrix embedded with particles of high remnant magnetic induction. Since the application of an external magnetic flux induces a body couple in HMSMs, the…

Numerical Analysis · Mathematics 2023-01-05 Farzam Dadgar-Rad , Mokarram Hossain

Segmentations are crucial in medical imaging to obtain morphological, volumetric, and radiomics biomarkers. Manual segmentation is accurate but not feasible in the radiologist's clinical workflow, while automatic segmentation generally…

Recent studies have shown that Machine Learning (ML) models can exhibit bias in real-world scenarios, posing significant challenges in ethically sensitive domains such as healthcare. Such bias can negatively affect model fairness, model…

Machine Learning · Computer Science 2025-09-05 Junyu Yan , Feng Chen , Yuyang Xue , Yuning Du , Konstantinos Vilouras , Sotirios A. Tsaftaris , Steven McDonagh

This paper presents simulations of the impact of tongue surgery on tongue movements and on speech articulation. For this, a 3D biomechanical Finite Element (FE) model of the tongue is used. Muscles are represented within the FE structure by…

Medical Physics · Physics 2007-10-16 Stéphanie Buchaillard , Muriel Brix , Pascal Perrier , Yohan Payan

Complex computer codes, for instance simulating physical phenomena, are often too time expensive to be directly used to perform uncertainty, sensitivity, optimization and robustness analyses. A widely accepted method to circumvent this…

Numerical Analysis · Mathematics 2011-04-22 Bertrand Iooss , Loïc Boussouf , Vincent Feuillard , Amandine Marrel

Clinical diffusion imaging requires short acquisition times and good image quality to permit its use in various medical applications. In turn, these demands require the development of a robust and efficient post-processing framework in…

Medical Physics · Physics 2015-02-18 Ivan I. Maximov , Farida Grinberg , Irene Neuner , N. Jon Shah

This document gives guidelines to set up, run, and postprocess correct simulations with the finite element method. It is not an introduction to the method itself, but rather a list of things to check and possible mistakes to watch out for…

Numerical Analysis · Computer Science 2018-11-15 Martin Bäker

Mammography is currently the primary imaging modality for breast cancer screening and plays an important role in cancer diagnostics. A standard mammographic image acquisition always includes the compression of the breast prior x-ray…

Computational biomechanics of the brain for neurosurgery is an emerging area of research recently gaining in importance and practical applications. This review paper presents the contributions of the Intelligent Systems for Medicine…

Computational Engineering, Finance, and Science · Computer Science 2019-04-03 K. Miller , G. R. Joldes , G. Bourantas , S. K. Warfield , D. E. Hyde , R. Kikinis , A. Wittek

Errors in biomechanics simulations arise from modeling and discretization. Modeling errors are due to the choice of the mathematical model whilst discretization errors measure the impact of the choice of the numerical method on the accuracy…

Computational Engineering, Finance, and Science · Computer Science 2020-03-04 Michel Duprez , Stéphane P. A. Bordas , Marek Bucki , Huu Phuoc Bui , Franz Chouly , Vanessa Lleras , Claudio Lobos , Alexei Lozinski , Pierre-Yves Rohan , Satyendra Tomar

While micro-CT systems are instrumental in preclinical research, clinical micro-CT imaging has long been desired with cochlear implantation as a primary example. The structural details of the cochlear implant and the temporal bone require a…

High-fidelity semantic segmentation of magnetic resonance volumes is critical for estimating tissue morphometry and relaxation parameters in both clinical and research applications. While manual segmentation is accepted as the…

Image and Video Processing · Electrical Eng. & Systems 2019-02-07 Arjun D. Desai , Garry E. Gold , Brian A. Hargreaves , Akshay S. Chaudhari

A computer simulation has to be fast to be helpful, if it is employed to study the behavior of a multicomponent dynamic system. This paper discusses modeling concepts and algorithmic techniques useful for creating such fast simulations.…

Data Structures and Algorithms · Computer Science 2007-05-23 Boris D. Lubachevsky

Statistical shape analysis of slabular objects like groups of hippocampi is highly useful for medical researchers as it can be useful for diagnoses and understanding diseases. This work proposes a novel object representation based on…

Methodology · Statistics 2024-09-09 Mohsen Taheri , Stephen M. Pizer , Jörn Schulz

Living soft tissues appear to promote the development and maintenance of a preferred mechanical state within a defined tolerance around a so-called set-point. This phenomenon is often referred to as mechanical homeostasis. In contradiction…

Computational Engineering, Finance, and Science · Computer Science 2021-09-23 Jonas F. Eichinger , Maximilian J. Grill , Iman Davoodi Kermani , Roland C. Aydin , Wolfgang A. Wall , Jay D. Humphrey , Christian J. Cyron

Surface-based cortical analysis is valuable for a variety of neuroimaging tasks, such as spatial normalization, parcellation, and gray matter (GM) thickness estimation. However, most tools for estimating cortical surfaces work exclusively…

Tuning the regularization hyperparameter $\alpha$ in inverse problems has been a longstanding problem. This is particularly true in the case of fetal brain magnetic resonance imaging, where an isotropic high-resolution volume is…

Image and Video Processing · Electrical Eng. & Systems 2023-04-06 Priscille de Dumast , Thomas Sanchez , Hélène Lajous , Meritxell Bach Cuadra