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Measuring the mechanical properties of cells and tissues often involves indentation with a sphere, or compression between two plates. Previously, different theoretical approaches have been developed to retrieve material parameters (e.g.…
Introduction: Mechanical thrombectomy can cause vessel deformation and procedure-related injury. Benchtop models are widely used for device testing, but time-resolved, full-field 3D vessel-motion measurements remain limited. Methods: We…
Fecal incontinence, arising from a myriad of pathogenic mechanisms, has attracted considerable global attention. Despite its significance, the replication of the defecatory system for studying fecal incontinence mechanisms remains limited…
A finite element formulation is developed for a poroelastic medium consisting of an incompressible hyperelastic skeleton saturated by an incompressible fluid. The governing equations stem from mixture theory and the application is motivated…
Connecting cell behavior to tissue shape and mechanics is a key challenge in the physics of morphogenesis. Cytoskeletal turnover precludes a fixed reference state, and tensions are actively generated independently of strain; so conventional…
This paper introduces a learning-based modeling framework for a magnetically steerable soft suction device designed for endoscopic endonasal brain tumor resection. The device is miniaturized (4 mm outer diameter, 2 mm inner diameter, 40 mm…
In this paper, we present a new polygonal finite element method, called the Zipped Finite Element Method, for star-shaped polygons. The proposed approach constructs high-order shape functions as linear combinations of standard finite…
The incidence of vertebral fragility fracture is increased by the presence of preexisting pathologies such as metastatic disease. Computational tools could support the fracture prediction and consequently the decision of the best medical…
Objective. (1) To assess whether neural tissue structure and biomechanics could predict functional loss in glaucoma; (2) To evaluate the importance of biomechanics in making such predictions. Design, Setting and Participants. We recruited…
We propose a novel projection method to treat near-incompressibility and volumetric locking in small- and large-deformation elasticity and plasticity within the context of higher order material point methods. The material point method is…
Source analysis of Electroencephalography (EEG) data requires the computation of the scalp potential induced by current sources in the brain. This so-called EEG forward problem is based on an accurate estimation of the volume conduction…
The effective macroscopic response of nonlinear elastomeric inhomogeneous materials is of great interest in many applications including nonlinear composite materials and soft biological tissues. The interest of the present work is…
Spin and orbital angular momenta are two intrinsic properties of an electron and are responsible for the physics of a solid. How the spin and orbital evolve with respect to each other on several hundred femtoseconds is largely unknown, but…
Knowledge of the mechanical properties of the aorta is essential as important concerns regarding the treatment of aortic pathologies, such as atherosclerosis, aneurysms and dissections, are fundamentally mechanobiological. A comprehensive…
This paper introduces a reduced-order modeling approach based on finite volume methods for hyperbolic systems, combining Proper Orthogonal Decomposition (POD) with the Discrete Empirical Interpolation Method (DEIM) and Proper Interval…
The classical problem of indentation on an elastic substrate has found new applications in the field of the Atomic Force Microscopy. However, linearly elastic indentation models are not sufficiently accurate to predict the…
In this work we propose a low rank approximation of high fidelity finite element simulations by utilizing weights corresponding to areas of high stress levels for an abdominal aortic aneurysm, i.e. a deformed blood vessel. We focus on the…
Optical coherence tomography (OCT) is a micrometer-scale, volumetric imaging modality that has become a clinical standard in ophthalmology. OCT instruments image by raster-scanning a focused light spot across the retina, acquiring…
In orthodontic treatment, the biological response of the tooth, periodontal ligament, and bone complex to orthodontic force is crucial in influencing treatment outcomes. The challenge lies in accurately measuring, estimating, and predicting…
Motion correction is an essential preprocessing step in functional Magnetic Resonance Imaging (fMRI) of the fetal brain with the aim to remove artifacts caused by fetal movement and maternal breathing and consequently to suppress erroneous…