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We numerically investigate the role of mechanical stress in modifying the conductivity properties of the cardiac tissue and its impact in computational models for cardiac electromechanics. We follow a theoretical framework recently proposed…

Tissues and Organs · Quantitative Biology 2019-05-02 A. Loppini , A. Gizzi , R. Ruiz Baier , C. Cherubini , F. Fenton , S. Filippi

Using Brownian Dynamics (BD) simulations we investigate non-equilibrium transitions of sheared colloidal films under controlled shear stress $\sigma_{\mathrm{xz}}$. In our approach the shear rate $\dot\gamma$ is a dynamical variable, which…

Soft Condensed Matter · Physics 2014-11-05 Tarlan A. Vezirov , Sascha Gerloff , Sabine H. L. Klapp

We present a numerical simulation study of a simple monatomic Lennard-Jones liquid under shear flow, as a function of both temperature and shear rate. By investigating different observables we find that i) It exists a line in the…

Soft Condensed Matter · Physics 2009-11-07 L. Angelani , G. Ruocco , F. Sciortino , P. Tartaglia , F. Zamponi

We investigate flow of incompressible fluid in a cylindrical tube with elastic walls. The radius of the tube may change along its length. The discussed problem is connected to the blood flow in large human arteries and especially to…

Fluid Dynamics · Physics 2015-09-30 Zlatinka I. Dimitrova

Patient-specific modeling of cardiovascular flows with high-fidelity is challenging due to its dependence on accurately estimated velocity boundary profiles, which are essential for precise simulations and directly influence wall shear…

Numerical Analysis · Mathematics 2024-11-28 Kabir Bakhshaei , Sajad Salavatidezfouli , Giovanni Stabile , Gianluigi Rozza

We numerically investigate the effect of entrance condition on the spatial and temporal evolution of multiple three-dimensional vortex pairs and wall shear stress distribution in a curved artery model. We perform this study using a…

Fluid Dynamics · Physics 2021-11-10 Christopher Cox , Michael W. Plesniak

Numerous are the questionings raised by medicine interventionnelle, concerning the hold in charge of the pathologies of the arterial partition (aneurysm, dissection, coarctation, atherosclerosis).for it we made the modeling and the numeric…

Fluid Dynamics · Physics 2009-06-29 H . Alla , M. S. Gueblaoui , M. H. Bensaid

A body immersed in a nematic liquid crystal disturbs the fluid's preferred molecular configuration and increases its stored elastic energy. In an active nematic, the fluid components also generate a stress in the bulk fluid. By introducing…

Soft Condensed Matter · Physics 2025-06-17 Thomas G. J. Chandler , Saverio E. Spagnolie

We present a novel approach to define the filter and relax steps in the evolve-filter-relax (EFR) framework for simulating turbulent flows. The EFR main advantages are its ease of implementation and computational efficiency. However, as it…

Predicting the flow of non-Newtonian fluids in porous structure is still a challenging issue due to the interplay betwen the microscopic disorder and the non-linear rheology. In this letter, we study the case of an yield stress fluid in a…

Soft Condensed Matter · Physics 2019-06-26 Chen Liu , Andrea De Luca , Alberto Rosso , Laurent Talon

Despite numerous studies on cerebral arterial blood flow, there has not yet been a comprehensive description of hemodynamics in patients undergoing debranching thoracic endovascular aortic repair (dTEVAR), a promising surgical option for…

Nonlinearities in constitutive equations of extended objects in shear flow lead to novel phenomena, {\it e.g.} "rheochaos" in solutions of wormlike micelles and "elastic turbulence" in polymer solutions. Since both phenomena involve…

Soft Condensed Matter · Physics 2019-08-20 Rituparno Mandal , Buddhapriya Chakrabarti , Debarshini Chakraborti , Chandan Dasgupta

An analytic, asymptotic approximation of the nonlinear steady-state equations for viscoelastic creeping flow, modeled by the Oldroyd-B equations with polymer stress diffusion, is derived. Near the extensional stagnation point the flow…

Fluid Dynamics · Physics 2016-01-14 Joseph A. Biello , Becca Thomases

Animal morphogenesis often involves significant shape changes of epithelial tissue sheets. Great progress has been made in understanding the underlying cellular driving forces and their coordination through biomechanical feedback loops.…

Soft Condensed Matter · Physics 2024-09-23 Nikolas H. Claussen , Fridtjof Brauns

We study a model describing the slow flow of a fluid through a deformable, porous, elastic solid undergoing small deformations. The stress-strain relationship of the solid incorporates nonlinear effects, formulated as a perturbation of the…

Numerical Analysis · Mathematics 2026-04-28 Andrea Bonito , Vivette Girault , Diane Guignard

Modeling and simulating how oxygen supply shapes neuronal excitability is crucial for advancing the understanding of brain function in pathological scenarios, such as ischemia. This condition is caused by a reduced blood supply, leading to…

Numerical Analysis · Mathematics 2026-03-19 Francesco Daniele , Caterina B. Leimer Saglio , Stefano Pagani , Paola F. Antonietti

The measurement of shear stress acting on a biologically relevant surface is a challenging problem, particularly in the complex environment of, for example, the vasculature. While an experimental method for the direct detection of wall…

Quantitative Methods · Quantitative Biology 2017-08-03 Meurig Thomas Gallagher , Cara Victoria Neal , Kenton P. Arkill , David John Smith

Computational fluid dynamics (CFD) is increasingly used to study blood flows in patient-specific arteries for understanding certain cardiovascular diseases. The techniques work quite well for relatively simple problems, but need…

Computational Physics · Physics 2018-10-11 Fande Kong , Vitaly Kheyfets , Ender Finol , Xiao-Chuan Cai

Hypertension is one of the most common age-related chronic diseases and by predisposing individuals for heart failure, stroke and kidney disease, it is a major source of morbidity and mortality. Its etiology remains enigmatic despite…

Tissues and Organs · Quantitative Biology 2015-06-15 Klas H. Pettersen , Scott M. Bugenhagen , Javaid Nauman , Daniel A. Beard , Stig W. Omholt

The aortic valve is a three-leaflet passive structure that, driven by pressure differences between the left ventricle and the aorta, opens and closes during the heartbeat to ensure the correct stream direction and flow rate. In elderly…

Fluid Dynamics · Physics 2021-03-30 Francesco Viola , Valentina Meschini , Roberto Verzicco