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The physical mechanism underlying the voltage-dependent gating of K channels is usually addressed theoretically using molecular dynamics simulations.However, besides being computationally very expensive, this approach is presently unable to…

Biological Physics · Physics 2020-01-08 Luigi Catacuzzeno , Fabio Franciolini

In this work we study the interaction of trapped ions with a state-dependent, high-intensity optical lattice formed above an ion trap chip using integrated photonics. We use a single ion to map the optical potential landscape over many…

Atomic Physics · Physics 2024-11-06 Alfredo Ricci Vasquez , Carmelo Mordini , Daniel Kienzler , Jonathan Home

`Gating' is a widely observed phenomenon in biochemistry that describes the transition between the activated (or open) and deactivated (or closed) states of an ion-channel, which makes transport through that channel highly selective. In…

Statistical Mechanics · Physics 2023-10-09 Arup Biswas , Arnab Pal , Debasish Mondal , Somrita Ray

Voltage gated channel proteins cooperate in the transmission of membrane potentials between nerve cells. With the recent progress in atomic-scaled biological chemistry it has now become established that these channel proteins provide highly…

Neurons and Cognition · Quantitative Biology 2012-06-11 Johann Summhammer , Vahid Salari , Gustav Bernroider

We introduce a Markov model for the gating of membrane channels. The model features a possible solution to the so-called gating current paradox, namely that the bell-shaped curve that describes the voltage dependence of the kinetics is…

Biological Physics · Physics 2007-05-23 L. P. Endresen , J. S. Hoye

Energy dispersion and spin orientation of the protected states at interfaces between topological insulators (TIs) and non-topological materials depend on the charge redistribution, strain, and atomic displacement at the interface. Knowledge…

Mesoscale and Nanoscale Physics · Physics 2020-09-29 Eklavya Thareja , Ilya Vekhter , Mahmoud M. Asmar

Modular mixed-species ion-trap networks are a promising framework for scalable quantum information processing, where one species acts as a memory qubit and another as a communication qubit. This architecture requires high-fidelity…

Quantum Physics · Physics 2021-02-03 Ksenia Sosnova , Allison Carter , Christopher Monroe

This paper is devoted mainly to mathematical aspects of modeling and simulation of tunnel relaxation of nonequilibrium charged oxide traps located at/near the interface insulator - conductive channel, for instance in irradiated MOS devices.…

Mesoscale and Nanoscale Physics · Physics 2017-02-01 Gennady I. Zebrev , Maxim G. Drosdetsky

Spectral crowding of collective motional modes limits the fidelity of entangling interactions in trapped-ion quantum processors by inducing off-resonant coupling to spectator modes. We introduce a geometric-phase entangling interaction…

We study stability of multiple conducting edge states in a topological insulator against all multi-particle perturbations allowed by the time-reversal symmetry. We model a system as a multi-channel Luttinger liquid, where the number of…

Strongly Correlated Electrons · Physics 2018-07-04 V. Kagalovsky , A. L. Chudnovskiy , I. V. Yurkevich

We exploit a simple one-dimensional trapping model introduced before, prompted by the problem of ion current across a biological membrane. The voltage-sensitive channels are open or closed depending on the value taken by an external…

Statistical Mechanics · Physics 2009-11-07 J. A. Revelli , A. D. Sanchez , H. S. Wio

Six thermo-activated transient receptor potential (TRP) channels are the molecular basis of the thermosensation for mammals. But the molecular source of their gating remains unknown. In the Letter, we suggest a physically based model for…

Biological Physics · Physics 2021-09-14 A. O. Okenov , B. I. Iaparov , A. S. Moskvin

Voltage distribution in sub-cellular micro-domains such as neuronal synapses, small protrusions or dendritic spines regulates the opening and closing of ionic channels, energy production and thus cellular homeostasis and excitability. Yet…

Subcellular Processes · Quantitative Biology 2024-07-23 Frédéric Paquin-Lefebvre , David Holcman

The role of orbital ordering on metal-insulator transition of transition-metal oxides is investigated by the cluster self-consistent field approach in the strong correlation regime. A clear dependence of the insulating gap on the orbital…

Strongly Correlated Electrons · Physics 2007-09-25 Dong-Meng Chen , Liang-Jian Zou

Voltage-activated ion channels vary randomly between open and closed states, influenced by the membrane potential and other factors. Signal transduction is enhanced by noise in a simple ion channel model. The enhancement occurs in a finite…

Biological Physics · Physics 2007-05-23 Michael J. Barber , Manfred L. Ristig

Excitability is an attribute of life, and is a driving force in the descent of complexity. Cellular electrical activity as realized by membrane proteins that act as either channels or transporters is the basis of excitability. Electrical…

Biomolecules · Quantitative Biology 2009-11-05 Ashok Palaniappan , Eric Jakobsson

Ion channels are specific proteins present in the membranes of living cells. They control the flow of specific ions through a cell, initiated by an ion channel's electrochemical gradient. In doing so, they control important physiological…

Subcellular Processes · Quantitative Biology 2012-09-14 Andrew Das Arulsamy

Diffusional dynamics of the donor-acceptor distance in electron-transfer reactions are responsible for the appearance of a new time scale of diffusion over the distance of falloff of electronic tunneling. The distance dynamics compete with…

Biological Physics · Physics 2022-09-21 Dmitry V. Matyushov

Following the paper by M. Combescure [Ann. Phys. (NY) 204, 113 (1990)], we apply the quantum singular time dependent oscillator model to describe the relative one dimensional motion of two ions in a trap. We argue that the model can be…

Quantum Physics · Physics 2009-10-30 V. V. Dodonov , V. I. Man'ko , L. Rosa

The study of selection and gating in potassium channels is a very important issue in modern biology. Indeed such structures are known in all types of cells in all organisms where they play many important functional roles. The mechanism of…

Cell Behavior · Quantitative Biology 2015-05-30 D. Andreucci , D. Bellaveglia , E. N. M. Cirillo , S. Marconi