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Related papers: Non-Markovian Stochastic Resonance: three state mo…

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We consider a two-state model of non-Markovian stochastic resonance (SR) within the framework of the theory of renewal processes. Residence time intervals are assumed to be mutually independent and characterized by some arbitrary…

Condensed Matter · Physics 2009-11-10 Igor Goychuk , Peter Hanggi

Aggregated Markov models provide a flexible framework for stochastic dynamics that develops on multiple timescales. For example, Markov models for ion channels often consist of multiple open and closed state to account for "slow" and "fast"…

Biomolecules · Quantitative Biology 2025-10-31 Ivo Siekmann

We identify a unifying measure for stochastic resonance (SR) in voltage dependent ion channels which comprises periodic (conventional), aperiodic and nonstationary SR. Within a simplest setting, the gating dynamics is governed by two-state…

Statistical Mechanics · Physics 2009-10-31 Igor Goychuk , Peter Hanggi

The phenomenological linear response theory of non-Markovian Stochastic Resonance (SR) is put forward for stationary two-state renewal processes. In terms of a derivation of a non-Markov regression theorem we evaluate the characteristic…

Statistical Mechanics · Physics 2007-05-23 Igor Goychuk , Peter Hanggi

We study a non Markovian three state model, subjected to an external periodic signal. This model is intended to describe an excitable systems with periodical driving. In the limit of a small amplitude of the external signal we derive…

Statistical Mechanics · Physics 2009-11-10 T. Prager , L. Schimansky-Geier

A position-dependent stochastic diffusion model of gating in ion channels is developed by considering the spatial variation of the diffusion coefficient between the closed and open states. It is assumed that a sensor which regulates the…

Mesoscale and Nanoscale Physics · Physics 2014-07-24 Samuel Robert Vaccaro

The physiology of voltage gated ion channels is complex and insights into their gating mechanism is incomplete. Their function is best represented by Markov models with relatively large number of distinct states that are connected by…

Subcellular Processes · Quantitative Biology 2013-12-17 Febe Francis , Míriam R. García , Oliver Mason , Richard H. Middleton

A discrete rate theory for general multi-ion channels is presented, in which the continuous dynamics of ion diffusion is reduced to transitions between Markovian discrete states. In an open channel, the ion permeation process involves three…

Biological Physics · Physics 2012-06-29 Wan Chen , Radek Erban , S. Jonathan Chapman

A model of mobile, charged ion channels in a fluid membrane is studied. The channels may switch between an open and a closed state according to a simple two-state kinetics with constant rates. The effective electrophoretic charge and the…

Soft Condensed Matter · Physics 2009-11-07 Stephan C. Kramer , Reiner Kree

In this paper we introduce a model which provides a new approach to the phenomenon of stochastic resonance. It is based on the study of the properties of the stationary distribution of the underlying stochastic process. We derive the…

Probability · Mathematics 2007-05-23 Peter Imkeller , Ilya Pavlyukevich

A statistical test is presented to decide whether data are adequately described by probabilistic functions of finite state Markov chains (''hidden Markov models'') as applied in the analysis of ion channel data. Particularly, the test can…

chao-dyn · Physics 2009-10-30 J. Timmer , S. Klein

We consider a charged Brownian particle in an asymmetric bistable electrostatic potential biased by an externally applied or induced time periodic electric field. While the amplitude of the applied field is independent of frequency, that of…

Biomolecules · Quantitative Biology 2009-03-04 Meir Shaked , Zeev Schuss

The two-state model of stochastic resonance is extended to a chain of coupled two-state elements governed by the dynamics of Glauber's stochastic Ising model. Appropriate assumptions on the model parameters turn the chain into a prototype…

Statistical Mechanics · Physics 2009-10-31 Udo Siewert , Lutz Schimansky-Geier

In this thesis we consider stochastic resonance for a diffusion with drift given by a potential, which has two metastable states and two pathways between them. Depending on the direction of the forcing the height of the two barriers, one…

Probability · Mathematics 2018-03-06 Tommy Liu

Stochastic resonance is a phenomenon where the response signal to external driving is enhanced by environment noise. In quantum regime, the effect of environment is often intrinsically non-Markovian. Due to the combination of such…

Mesoscale and Nanoscale Physics · Physics 2023-03-17 Ruofan Chen , Xiansong Xu

We consider an exactly tractable model of the Kramers type for the voltage-dependent gating dynamics of single ion channels. It is assumed that the gating dynamics is caused by the thermally activated transitions in a bistable potential.…

Biological Physics · Physics 2009-11-11 Igor Goychuk , Peter Hanggi

We investigate the stochastic resonance phenomenon in a physical system based on a tunnel diode. The experimental control parameters are set to allow the control of the frequency and amplitude of the deterministic modulating signal over an…

Statistical Mechanics · Physics 2009-10-31 Rosario N. Mantegna , Bernardo Spagnolo , Marco Trapanese

We study the non-Markovian dynamics of a two-mode bosonic system interacting with two uncorrelated thermal bosonic reservoirs. We present the solution to the exact microscopic Master equation in terms of the quantum characteristic function…

Quantum Physics · Physics 2007-07-04 Sabrina Maniscalco , Stefano Olivares , Matteo G. A. Paris

Markov processes are shown to be consistent with metastable states seen in pulsar phenomena, including intensity nulling, pulse-shape mode changes, subpulse drift rates, spindown rates, and X-ray emission, based on the typically broad and…

High Energy Astrophysical Phenomena · Physics 2015-06-15 J. M. Cordes

The contributions of independent noise sources to the variability of action potential timing has not previously been studied at the level of individual directed molecular transitions within a conductance-based model ion-state graph. The…

Neurons and Cognition · Quantitative Biology 2020-11-18 Shusen Pu , Peter J. Thomas
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