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A general method for computing kinetic isotope effects is described. The method uses the quantum-instanton approximation and is based on the thermodynamic integration with respect to the mass of the isotopes and on the path-integral…

Chemical Physics · Physics 2007-05-23 Jiri Vanicek , William H. Miller

Path integral implementation of the quantum instanton approximation currently belongs among the most accurate methods for computing quantum rate constants and kinetic isotope effects, but its use has been limited due to the rather high…

Chemical Physics · Physics 2017-05-10 Konstantin Karandashev , Jiri Vanicek

Ab initio instanton rate theory is a computational method for rigorously including tunnelling effects into calculations of chemical reaction rates based on a potential-energy surface computed on the fly from electronic-structure theory.…

Chemical Physics · Physics 2018-05-08 Gabriel Laude , Danilo Calderini , David P. Tew , Jeremy O. Richardson

Ring-polymer instanton theory has been developed to simulate the quantum dynamics of molecular systems at low temperatures. Chemical reaction rates can be obtained by locating the dominant tunneling pathway and analyzing fluctuations around…

Chemical Physics · Physics 2019-03-25 Pierre Winter , Jeremy O. Richardson

We explore the relation between the quantum and semiclassical instanton approximations for the reaction rate constant. From the quantum instanton expression, we analyze the contributions to the rate constant in terms of minimum-action paths…

Chemical Physics · Physics 2019-10-16 Christophe L. Vaillant , Manish J. Thapa , Jiří Vaníček , Jeremy O. Richardson

Canonical instanton theory is a widespread approach to describe the dynamics of chemical reactions in low temperature environments when tunneling effects become dominant. It is a semiclassical theory which requires locating classical…

Chemical Physics · Physics 2020-09-15 Andreas Löhle , Johannes Kästner

We present a general quantum instanton approach to calculating reaction rates for systems with two electronic states and arbitrary values of the electronic coupling. This new approach, which we call the non-adiabatic quantum instanton…

Chemical Physics · Physics 2020-05-29 Joseph E. Lawrence , David E. Manolopoulos

Instanton theory is an established method to calculate rate constants of chemical reactions including atom tunneling. Technical and methodological improvements increased its applicability. Still, a large number of energy and gradient…

Chemical Physics · Physics 2020-09-10 Jan Meisner , Johannes Kästner

A general method for the direct evaluation of the temperature dependence of the quantum-mechanical reaction rate constant in many-dimensional systems is described. The method is based on the quantum instanton approximation for the rate…

Chemical Physics · Physics 2013-01-15 Marcin Buchowiecki , Jiri Vanicek

Simulation of surface processes is a key part of computational chemistry that offers atomic-scale insights into mechanisms of heterogeneous catalysis, diffusion dynamics, as well as quantum tunneling phenomena. The most common theoretical…

Chemical Physics · Physics 2023-05-01 Wei Fang , Yu-Cheng Zhu , Yi-Han Cheng , Yi-Ping Hao , Jeremy O. Richardson

In the instanton models the chiral phase transition is driven by a transition from random instanton-antiinstanton liquid and correlated instanton-antiinstanton molecules. So far this phenomenon was studied by numerical simulations, while we…

High Energy Physics - Phenomenology · Physics 2014-11-17 M. Velkovsky , E. Shuryak

Convergence of path integral simulations requires a substantial number of beads when quantum effects are significant. Traditional Trotter scaling approaches estimate the continuum limit through extrapolation, however they are restricted to…

Statistical Mechanics · Physics 2024-05-28 Sabry G Moustafa

A general and rigorous methodology to compute the quantum equilibrium isotope effect is described. Unlike standard approaches, ours does not assume separability of rotational and vibrational motions and does not make the harmonic…

Chemical Physics · Physics 2015-05-13 Tomas Zimmermann , Jiri Vanicek

The shift in chemical equilibria due to isotope substitution is often exploited to gain insight into a wide variety of chemical and physical processes. It is a purely quantum mechanical effect, which can be computed exactly using…

Statistical Mechanics · Physics 2014-07-04 Michele Ceriotti , Thomas E. Markland

Instanton rate theory is used to study tunneling events in a wide range of systems including low-temperature chemical reactions. Despite many successful applications, the method has never been obtained from first principles, relying instead…

Chemical Physics · Physics 2016-09-05 Jeremy O. Richardson

We first show that a simple scaling of fluctuation coordinates defined in terms of a given reference point gives the conventional virial estimator in discretized path integral, where different choices of the reference point lead to…

Chemical Physics · Physics 2009-11-11 Takeshi M. Yamamoto

We numericaly demonstrate that, in double well models, the autocorrelation time of open path integral Monte Carlo simulations can be much smaller compared to standard ones using ring polymers. We also provide an intuitive explanation based…

Computational Physics · Physics 2016-08-04 Guglielmo Mazzola , Matthias Troyer

Semiclassical instanton theory is a form of quantum transition-state theory which can be applied to computing thermal reaction rates for complex molecular systems including quantum tunneling effects. There have been a number of attempts to…

Chemical Physics · Physics 2020-10-28 Wei Fang , Pierre Winter , Jeremy O. Richardson

We review the euclidean path-integral formalism in connection with the one-dimensional non-relativistic particle. The configurations which allow to construct a semiclassical approximation classify themselves into either topological…

High Energy Physics - Theory · Physics 2007-05-23 J. Casahorran

Fractionation of isotopes among distinct molecules or phases is a quantum effect which is often exploited to obtain insights on reaction mechanisms, biochemical, geochemical and atmospheric phenomena. Accurate evaluation of isotope ratios…

Chemical Physics · Physics 2015-06-23 Bingqing Cheng , Michele Ceriotti
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