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A healthy human brain is perfused with blood flowing laminarly through cerebral vessels, providing brain tissue with substrates such as oxygen and glucose. Under normal conditions, cerebral blood flow is controlled by autoregulation as well…

Other Quantitative Biology · Quantitative Biology 2007-05-23 Miroslaw Latka , Malgorzata Turalska , Waldemar Kolodziej , Dariusz Latka , Brahm Goldstein , Bruce J. West

Cerebral arterial blood flow (CABF) can be investigated in few seconds without any synchronization by Real-Time phase contrast. Significant changes in CABF were found between expiration and inspiration during normal breathing of healthy…

Signal Processing · Electrical Eng. & Systems 2022-07-27 Pan Liu , Sidy Fall , Serge Metanbou , Olivier Balédent

Atrial fibrillation (AF) is associated with cognitive impairment/dementia, independently of clinical cerebrovascular events (stroke/TIA). One of the plausible mechanisms is the occurrence of AF-induced transient critical hemodynamic events;…

Medical Physics · Physics 2019-03-11 Andrea Saglietto , Stefania Scarsoglio , Luca Ridolfi , Fiorenzo Gaita , Matteo Anselmino

Heart rate variability (HRV), defined as the variability between consecutive heartbeats, is a surrogate measure of cardiac vagal tone. It is widely accepted that a decreased HRV is associated to several risk factors and cardiovascular…

Medical Physics · Physics 2021-05-20 Stefania Scarsoglio , Luca Ridolfi

Cardiovascular disease (CVD) is a leading cause of morbidity and mortality worldwide, and sustained hypertension is an often silent risk factor, making cuffless continuous blood pressure (BP) monitoring with wearable devices important for…

Signal Processing · Electrical Eng. & Systems 2025-12-02 Yiqiao Chen , Fazheng Xu , Zijian Huang , Juchi He , Zhenghui Feng

Pulse transit time (PTT) has been widely used for cuffless blood pressure (BP) measurement. But, it requires more than one cardiovascular signals involving more than one sensing device. In this paper, we propose a method for continuous…

Signal Processing · Electrical Eng. & Systems 2024-05-07 Mousumi Das , Tilendra Choudhary , L. N. Sharma , M. K. Bhuyan

This paper presents a novel blood pressure (BP) estimation method based on pulse transit time (PTT) and pulse arrival time (PAT) to estimate the systolic BP (SBP) and the diastolic BP (DBP). A data acquisition hardware is designed for…

Signal Processing · Electrical Eng. & Systems 2019-05-08 Amirhossein Esmaili , Mohammad Kachuee , Mahdi Shabany

Blood pressure (BP) changes are linked to individual health status in both clinical and non-clinical settings. This study developed a deep learning model to classify systolic (SBP), diastolic (DBP), and mean (MBP) BP changes using…

Signal Processing · Electrical Eng. & Systems 2024-07-04 Jingyuan Hong , Manasi Nandi , Weiwei Jin , Jordi Alastruey

Using a three-compartment model of blood pressure dynamics, we analyze theoretically the short term cardiovascular variability: how the respiratory-related blood pressure fluctuations are buffered by appropriate heart rate changes: i.e. the…

Medical Physics · Physics 2010-07-15 Teodor Buchner , Jan Żebrowski , Grzegorz Gielerak

Blood Pressure (BP) and Heart Rate (HR) provide information on clin-ical condition along 24h. Both signals present circadian changes due to sympa-thetic/parasympathetic control system that influence the relationship between them. Moreover,…

Signal Processing · Electrical Eng. & Systems 2020-11-24 Giulia Silveri , Lorenzo Pascazio , Milos Ajcevic , Aleksandar Miladinovic , Agostino Accardo

Accurate and continuous blood pressure (BP) monitoring is essential to the early prevention of cardiovascular diseases. Non-invasive and cuff-less BP estimation algorithm has gained much attention in recent years. Previous studies have…

Machine Learning · Computer Science 2023-11-27 Bufang Yang , Le Liu , Wenxuan Wu , Mengliang Zhou , Hongxing Liu , Xinbao Ning

The clinical and economic burden of cardiovascular diseases (CVDs) poses a global challenge. Growing evidence suggests an early assessment of arterial stiffness can provide insights into the pathogenesis of CVDs. However, it remains…

Medical Physics · Physics 2020-12-07 Guo-Yang Li , Yuxuan Jiang , Yang Zheng , Weiqiang Xu , Zhaoyi Zhang , Yanping Cao

It is shown that the dependence of the cerebral blood flow (CBF) on mean arterial blood pressure (MABP) can be described with a simple model having the following assumptions. Below certain MABP (denoted as MABP1) there are no autoregulatory…

Biological Physics · Physics 2011-03-30 Alexander Gersten

Prenatal maternal stress alters maternal-fetal heart rate coupling, as demonstrated by the Fetal Stress Index derived from bivariate phase-rectified signal averaging. Here, we extend this framework using information-theoretical measures to…

Quantitative Methods · Quantitative Biology 2026-01-05 Nicolas B. Garnier , Maria S. Molinet , Marta C. Antonelli , Silvia M. Lobmaier , Martin G. Frasch

Dynamic cerebral autoregulation, that is the transient response of cerebral blood flow to changes in arterial blood pressure, is currently assessed using a variety of different time series methods and data collection protocols. In the…

Quantitative Methods · Quantitative Biology 2017-05-16 Adam Mahdi , Dragana Nikolic , Anthony A. Birch , Mette S. Olufsen , Ronney B. Panerai , David M. Simpson , Stephen J. Payne

Background. Different mechanisms have been proposed to relate atrial fibrillation (AF) and coronary flow impairment, even in absence of relevant coronary artery disease (CAD). However, the underlying hemodynamics remains unclear. Aim of the…

Medical Physics · Physics 2019-04-17 Stefania Scarsoglio , Caterina Gallo , Andrea Saglietto , Luca Ridolfi , Matteo Anselmino

The average wavelet coefficient method is applied to investigate the scaling features of heart rate variability during meditation, a state of induced mental relaxation. While periodicity dominates the behavior of the heart rate time series…

Biological Physics · Physics 2009-01-28 Nikitas Papasimakis , Fotini Pallikari

Aims. Clinical data indicating a heart rate (HR) target during rate control therapy for permanent atrial fibrillation (AF) and assessing its eventual relationship with reduced exercise tolerance are lacking. The present study aims at…

Medical Physics · Physics 2017-01-17 Matteo Anselmino , Stefania Scarsoglio , Andrea Saglietto , Fiorenzo Gaita , Luca Ridolfi

The use of office measurement of Blood Pressure (BP) as well as of the mean on day-time, on night-time or on 24h does not accurately describe the changes of the BP circadian rhythm. Moreover, several risk factors affect this rhythm but…

Efficient management of low blood pressure (BP) in preterm neonates remains challenging with a considerable variability in clinical practice. The ability to assess preterm wellbeing during episodes of low BP will help to decide when and…

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