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In positron emission tomography (PET), time-of-flight (TOF) information localizes source positions along lines of response. Cherenkov-radiator-integrated microchannel-plate photomultiplier tubes have achieved 30 ps TOF resolution,…

Recent development of photon-counting CT (PCCT) brings great opportunities for plaque characterization with much-improved spatial resolution and spectral imaging capability. While existing coronary plaque PCCT imaging results are based on…

Medical Physics · Physics 2023-12-05 Mengzhou Li , Mingye Wu , Jed Pack , Pengwei Wu , Bruno De Man , Adam Wang , Koen Nieman , Ge Wang

Results from the simulations of a Compton gamma camera based on compact configuration of detectors consisting in two detection modules, each of them having two stages of high-resolution position- and energy-sensitive radiation detectors…

Medical Physics · Physics 2018-02-15 L. Caballero

Currently inorganic scintillator detectors are used in all commercial Time of Flight Positron Emission Tomograph (TOF-PET) devices. The J-PET collaboration investigates a possibility of construction of a PET scanner from plastic…

Photon-counting energy resolving detectors are subject to intense research interest, and there is a need for a general framework for performance assessment of these detectors. The commonly used linear-systems theory framework, which…

Medical Physics · Physics 2019-12-18 Mats Persson , Paurakh L. Rajbhandary , Norbert J. Pelc

X-ray fluorescence computed tomography based on sheet-beam can save a huge amount of time to obtain a whole set of projections using synchrotron. However, it is clearly unpractical for most biomedical research laboratories. In this paper,…

Medical Physics · Physics 2017-03-07 Shanghai Jiang , Peng He , Luzhen Deng , Mianyi Chen , Biao Wei

We are investigating a prototype virtual pinhole positron emission tomography (VP-PET) system for small animal imaging applications. The PET detector modules were made up of 1.3 mm lutetium-yttrium oxyorthosilicate (LYSO) arrays, and the…

Medical Physics · Physics 2018-01-11 Zheng-Qian Ye , Ying-Guo Li , Tian-Quan Wang , Ya-Ming Fan , Yong-Zhi Yin , Xi-Meng Chen

Positron Emission Tomography (PET) scanners are usually designed with the goal to obtain the best compromise between sensitivity, resolution, field-of-view size, and cost. Therefore, it is difficult to improve the resolution of a PET…

Medical Physics · Physics 2023-07-18 Pablo Galve , Alejandro Lopez-Montes , Jose M Udias , Stephen C Moore , Joaquin L Herraiz

Time of Flight Positron Emission Tomography scanner based on plastic scintillators is being developed at the Jagiellonian University by the J-PET collaboration. The main challenge of the conducted research lies in the elaboration of a…

Purpose: To demonstrate a proton imaging system based on well-established fast scintillator technology to achieve high performance with low cost and complexity, with the potential of a straightforward translation into clinical use. Methods:…

Analyses of gamma-ray spectra, acquired through non-invasive techniques, have found applications in fields such as medicine, industry and homeland security. Constituent gamma-ray spectra of a chemical compound have been determined from its…

In this paper we use detailed Monte Carlo simulations to demonstrate that liquid xenon (LXe) can be used to build a Cherenkov-based TOF-PET, with an intrinsic coincidence resolving time (CRT) in the vicinity of 10 ps. This extraordinary…

Instrumentation and Detectors · Physics 2017-10-11 Juan Jose Gomez-Cadenas , José María Benlloch-Rodríguez , Paola Ferrario

In current practice, scene survey is carried out by workers using total stations. The method has high accuracy, but it incurs high costs if continuous monitoring is needed. Techniques based on photogrammetry, with the relatively cheaper…

Computer Vision and Pattern Recognition · Computer Science 2021-11-11 Kwok-Leung Chan , Liping Li , Arthur Wing-Tak Leung , Ho-Yin Chan

Low-resolution and signal-dependent noise distribution in positron emission tomography (PET) images makes denoising process an inevitable step prior to qualitative and quantitative image analysis tasks. Conventional PET denoising methods…

Computer Vision and Pattern Recognition · Computer Science 2014-07-14 Awais Mansoor , Ulas Bagci , Daniel J. Mollura

We have performed a Monte-Calro simulation for Galactic population of pulsars and for the $\gamma$-ray observations. We apply outer gap model for the $\gamma$-ray emission process, and study the radiation characteristics as a function of…

High Energy Astrophysical Phenomena · Physics 2015-05-27 J. Takata , Y. Wang , K. S. Cheng

The use of computed tomography (CT) imaging has become of increasing interest to academic areas outside of the field of medical imaging and industrial inspection, e.g., to biology and cultural heritage research. The pecularities of these…

Image and Video Processing · Electrical Eng. & Systems 2020-11-16 Florian Schiffers , Thomas Bochynek , Andre Aichert , Tobias Würfl , Michael Rubenstein , Oliver Cossairt

Properties of response functions of room temperature gamma-radiation detectors based on wide band-gap semiconductors are researched using Monte-Carlo method. It is shown that approximate formulas which connect detector sensitivity with…

Instrumentation and Detectors · Physics 2012-07-24 Alexandr A. Zakharchenko

A Monte Carlo simulation has been developed to predict the spatial resolution of silicon pixel detectors. The results discussed in this paper focus on the unit cell geometry of 50 $\mu$m x 400 $\mu$m, as chosen for BTeV. Effects taken into…

High Energy Physics - Experiment · Physics 2009-10-31 Marina Artuso , Jianchun Wang

A simple Monte Carlo (MC) algorithm for the simulation of the passage of low-energy gamma rays and electrons through any material medium is presented. The algorithm includes several approximations that accelerate the simulation while…

Accelerator Physics · Physics 2023-10-25 Víctor Moya , Jaime Rosado , Fernando Arqueros

SPECT (Single-photon Emission Computerized Tomography) and PET (Positron Emission Tomography) are essential medical imaging tools, for which the sampling angle number, scan time should be chosen carefully to compromise between image quality…

Medical Physics · Physics 2015-06-16 Xiaolin Zhou , Minkai Yun , Xuexiang Cao , Shuangquan Liu , Lu Wang , Xianchao Huang , Long Wei