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We consider the problem of optical tomographic imaging in the mesoscopic regime where the photon mean free path is of order of the system size. Within the accuracy of the single-scattering approximation to the radiative transport equation,…

Medical Physics · Physics 2009-04-29 Lucia Florescu , John C. Schotland , Vadim A. Markel

Optical diffraction tomography (ODT) is a three-dimensional (3D) quantitative phase imaging technique, which enables the reconstruction of the 3D refractive index (RI) distribution of a transparent sample. Due to its fast, non-invasive, and…

Optics · Physics 2018-11-14 Chansuk Park , Seungwoo Shin , Yongkeun Park

Overcoming diffraction limit is crucial for obtaining high-resolution image and observing fine microstructure. With this conventional difficulty still puzzling us and the prosperous development of wave dynamics of light interacting with…

Optics · Physics 2023-08-21 Jingxuan Zhang , Chenni Xu , Patrick Sebbah , Li-Gang Wang

Optical diffraction tomography is an indispensable tool for studying objects in three-dimensions due to its ability to accurately reconstruct scattering objects. Until now this technique has been limited to coherent light because spatial…

An ideal imaging system provides a spatial resolution that is ultimately dictated by the numerical aperture (NA) of the illumination and collection optics. In biological tissue, resolution is further affected by scattering limiting the…

We consider the inverse problem of reconstructing the scattering coefficient of a simple radiative transport equation (RTE) used to model light propagation inside a scattering medium. To do so, we extract information from the second term in…

Analysis of PDEs · Mathematics 2025-08-07 Francis Chung , Faith Hensley

Light scattering by tissue severely limits how deep beneath the surface one can image, and the spatial resolution one can obtain from these images. Diffuse optical tomography (DOT) is one of the most powerful techniques for imaging deep…

Image and Video Processing · Electrical Eng. & Systems 2021-05-31 Yongyi Zhao , Ankit Raghuram , Hyun K. Kim , Andreas H. Hielscher , Jacob T. Robinson , Ashok Veeraraghavan

We demonstrate that simultaneous reconstruction of scattering and absorption of a mesoscopic system using angularly-resolved measurements of scattered light intensity is possible. Image reconstruction is realized based on the algebraic…

Optics · Physics 2011-01-07 Lucia Florescu , John C. Schotland , Vadim A. Markel

Many naturally-occuring models in the sciences are well-approximated by simplified models, using multiscale techniques. In such settings it is natural to ask about the relationship between inverse problems defined by the original problem…

Numerical Analysis · Mathematics 2019-02-28 Kit Newton , Qin Li , Andrew Stuart

This article addresses gaps in definitions and a lack of standard measurement techniques to assess the spatial resolution in atom probe tomography. This resolution is known to be anisotropic, being better in the depth than laterally.…

In this paper we construct numerical schemes to approximate linear transport equations with slab geometry by diffusion equations. We treat both the case of pure diffusive scaling and the case where kinetic and diffusive scalings coexist.…

Numerical Analysis · Mathematics 2015-05-18 Qin Li , Jianfeng Lu , Weiran Sun

Omni-resonance refers to the broadening of the spectral transmission through a planar cavity, not by changing the cavity structure, but by judiciously preconditioning the incident optical field. As such, broadband imaging can be performed…

Optics · Physics 2022-08-17 Abbas Shiri , Ayman F. Abouraddy

Imaging of scenes using light or other wave phenomena is subject to the diffraction limit. The spatial profile of a wave propagating between a scene and the imaging system is distorted by diffraction resulting in a loss of resolution that…

Image and Video Processing · Electrical Eng. & Systems 2020-07-20 Ji Hyun Nam , Andreas Velten

For more than a century, the diffraction limit has defined the resolution achievable by passive optical imaging systems. Although some resolution improvement can be gained through classical data processing of the image, it is limited by the…

Quantum Physics · Physics 2026-05-12 A. I. Lvovsky , Michael R. Grace , Saikat Guha , Mankei Tsang , Gerardo Adesso , Nicolas Treps

This paper is a review of recent mathematical and computational advances in optical tomography. We discuss the physical foundations of forward models for light propagation on microscopic, mesoscopic and macroscopic scales. We also consider…

Analysis of PDEs · Mathematics 2009-07-16 Simon Arridge , John Schotland

We proposed a method to achieve superresolved optical imaging without beating the diffraction limit of light. This is achieved by magnifying the ideal optical image of the object through higher-order spatial frequency generation while…

Optics · Physics 2016-08-08 Zhixiang Li , Jianji Liu , Guoquan Zhang

Spatial resolution in optical microscopy has traditionally been treated as a fixed parameter of the optical system. Here, we present an approach to enhance transverse resolution in beam-scanned optical coherence tomography (OCT) beyond its…

Optics · Physics 2021-10-22 Nichaluk Leartprapun , Steven G. Adie

We investigate analytically and numerically the role of quantum fluctuations in reconstruction of optical objects from diffraction-limited images. Taking as example of an input object two closely spaced Gaussian peaks we demonstrate that…

Quantum Physics · Physics 2009-11-10 Vladislav N. Beskrovnyy , Mikhail I. Kolobov

Atom probe tomography (APT) is often quoted to provide "atomic-scale" analysis of materials in three dimensions. Despite efforts to quantify APT's spatial resolution, misunderstanding remain regarding its true spatial performance. If the…

No imaging apparatus can produce perfect images: spatial resolution is limited by the Rayleigh diffraction bound that is a consequence of the imager's finite spatial extent. We show some N-photon strategies that permit resolution of details…

Quantum Physics · Physics 2009-02-25 Vittorio Giovannetti , Seth Lloyd , Lorenzo Maccone , Jeffrey H. Shapiro
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