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Cells self-organize into functional, ordered structures during tissue morphogenesis, a process that is evocative of colloidal self-assembly into engineered soft materials. Understanding how inter-cellular mechanical interactions may drive…

Fiber-reinforcement is a universal feature of many biological tissues. It involves the interplay between fiber stiffness, fiber orientation, and the elastic properties of the matrix, influencing pattern formation and evolution in layered…

Soft Condensed Matter · Physics 2025-04-29 Yang Liu , Rui-Cheng Liu , Wanyu Ma , Alain Goriely

In the growth of bacterial colonies, a great variety of complex patterns are observed in experiments, depending on external conditions and the bacterial species. Typically, existing models employ systems of reaction-diffusion equations or…

Biological Physics · Physics 2019-11-12 Lautaro Vassallo , David Hansmann , Lidia A. Braunstein

Confined thin structures are ubiquitous in nature. Spatial and length constraints have led to a number of novel packing strategies at both the micro-scale, as when DNA packages inside a capsid, and the macro-scale, seen in plant root…

Soft Condensed Matter · Physics 2019-11-28 David J. Schunter, , Regina K. Czech , Douglas P. Holmes

The tribology of a sliding elastic continuum in contact with a disordered substrate is investigated analytically and numerically via a bead-spring model. The deterministic dynamics of this system exhibits a depinning transition at a finite…

Condensed Matter · Physics 2009-10-28 D. Cule , T. Hwa

The paper studies a PDE model for the growth of a tree stem or a vine, having the form of a differential inclusion with state constraints. The equations describe the elongation due to cell growth, and the response to gravity and to external…

Optimization and Control · Mathematics 2017-04-13 Bressan Alberto , Palladino Michele

Networks of filamentous proteins play a crucial role in cell mechanics. These cytoskeletal networks, together with various crosslinking and other associated proteins largely determine the (visco)elastic response of cells. In this letter we…

Disordered Systems and Neural Networks · Physics 2009-11-10 D. A. Head , A. J. Levine , F. C. MacKintosh

Ferrogels and magnetoelastomers are composite materials obtained by embedding magnetic particles of mesoscopic size in a crosslinked polymeric matrix. They combine the reversible elastic deformability of polymeric materials with the high…

We study the compression of bundles of aligned macroscopic fibers with intrinsic shape disorder, as found in human hair and in many other natural and man-made systems. We show by a combination of experiments, numerical simulations and…

Cells moving on a two dimensional substrate generate motion by polymerizing actin filament networks inside a flat membrane protrusion. New filaments are generated by branching off existing ones, giving rise to branched network structures.…

Biological Physics · Physics 2015-06-29 Mohammadhosein Razbin , Martin Falcke , Panayotis Benetatos , Annette Zippelius

The interstellar medium is threaded by a hierarchy of filaments from large scales (~ 100 pc) to small scales (~ 0.1pc). The masses and lengths of these nested structures may reveal important constraints for cloud formation and evolution,…

Astrophysics of Galaxies · Physics 2024-02-09 Jiancheng Feng , Rowan J. Smith , Alvaro Hacar , Susan E. Clark , Daniel Seifried

Spontaneous stratification of granular mixtures has been reported by Makse et al. [Nature 386, 379 (1997)] when a mixture of grains differing in size and shape is poured in a quasi-two-dimensional heap. We study this phenomenon using two…

Statistical Mechanics · Physics 2009-10-31 Pierre Cizeau , Hernan A. Makse , H. Eugene Stanley

Unlike most synthetic materials, biological materials often stiffen as they are deformed. This nonlinear elastic response, critical for the physiological function of some tissues, has been documented since at least the 19th century, but the…

Soft Condensed Matter · Physics 2009-11-10 Cornelis Storm , Jennifer J. Pastore , Fred C. MacKintosh , Tom C. Lubensky , Paul A. Janmey

During animal development and homeostasis, the structure of tissues, including muscles, blood vessels and connective tissues adapts to mechanical strains in the extracellular matrix (ECM). These strains originate from the differential…

Cell Behavior · Quantitative Biology 2017-03-06 Elisabeth G. Rens , Roeland M. H. Merks

We discuss the formation of graded morphogen profiles in a cell layer by nonlinear transport phenomena, important for patterning developing organisms. We focus on a process termed transcytosis, where morphogen transport results from binding…

Other Quantitative Biology · Quantitative Biology 2007-05-23 T. Bollenbach , K. Kruse , P. Pantazis , M. González-Gaitán , F. Jülicher

In this work, a new model for macroscopic plant tissue growth based on dynamical Riemannian geometry is presented. We treat 1D and 2D tissues as continuous, deformable, growing geometries for sizes larger than 1mm. The dynamics of the…

Tissues and Organs · Quantitative Biology 2016-02-05 Julia Pulwicki

Advanced modern technology and industrial sustainability theme have contributed implementing composite materials for various industrial applications. Green composites are among the desired alternatives for the green products. However, to…

Neural and Evolutionary Computing · Computer Science 2024-04-12 Faris M. AL-Oqla , Hossam Faris , Maria Habib , Pedro A. Castillo-Valdivieso

We present theoretical and experimental studies of the elastic response of fibrous networks subjected to uniaxial strain. Uniaxial compression or extension is applied to extracellular networks of fibrin and collagen using a shear rheometer…

Pattern formation and the mechanics of a mixture of actin filaments and myosin motors that is confined by a rigid membrane is investigated. By using a coarse-grained molecular dynamics model, we demonstrate that the competition between the…

Soft Condensed Matter · Physics 2023-04-12 Mitsusuke Tarama , Tatsuo Shibata

We present a statistical mechanical study of stiff polymers, motivated by experiments on actin filaments and the considerable current interest in polymer networks. We obtain simple, approximate analytical forms for the force-extension…

Soft Condensed Matter · Physics 2009-11-13 Abhijit Ghosh , Joseph Samuel , Supurna Sinha
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