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Related papers: Chirality Selection Models in a Closed System

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As an attempt to understand the homochirality of organic molecules in life, a chemical reaction model is proposed where the production of chiral monomers from achiral substrate is catalyzed by the polymers of the same enatiomeric type. This…

Biological Physics · Physics 2007-07-20 Yukio Saito , Hiroyuki Hyuga

Theoretical models and rate equations relevant to the Soai reaction are reviewed. It is found that in a production of chiral molecules from an achiral substrate autocatalytic processes can induce either enantiomeric excess (ee)…

Statistical Mechanics · Physics 2007-05-23 Yukio Saito , Hiroyuki Hyuga

We solve numerically a kinetic model of chiral polymerization in systems closed to matter and energy flow, paying special emphasis to its ability to amplify the small initial enantiomeric excesses due to the internal and unavoidable…

Quantitative Methods · Quantitative Biology 2017-03-15 Celia Blanco , David Hochberg

Stochastic aspects of chemical reaction models related to the Soai reactions as well as to the homochirality in life are studied analytically and numerically by the use of the master equation and random walk model. For systems with a…

Statistical Mechanics · Physics 2007-07-20 Yukio Saito , Takeshi Sugimori , Hiroyuki Hyuga

A nonlinear autocatalysis of a chiral substance is shown to achieve homochirality in a closed system, if the back-reaction is included. Asymmetry in the concentration of two enantiomers or the enantiometric excess increases due to the…

Chemical Physics · Physics 2008-11-26 Yukio Saito , Hiroyuki Hyuga

Living systems have evolved to efficiently consume available energy sources using an elaborate circuitry of chemical reactions which, puzzlingly, bear a strict restriction to asymmetric chiral configurations. While autocatalysis is known to…

Chemical Physics · Physics 2022-05-25 William D. Piñeros , Tsvi Tlusty

To understand the chirality selection in the biological organic system, a simple lattice model of chemical reaction with molecular diffusion is proposed and studied by Monte Carlo simulations. In addition to a simple stochastic process of…

Chemical Physics · Physics 2007-07-20 Yukio Saito , Hiroyuki Hyuga

A recently proposed model of non-autocatalytic reactions in dipeptide reactions leading to spontaneous symmetry breaking and homochirality is examined. The model is governed by activation, polymerization, epimerization and depolymerization…

Biomolecules · Quantitative Biology 2007-11-01 Axel Brandenburg , Harry J. Lehto , Kirsi M. Lehto

A material with symmetry breaking inside can transmit the symmetry breaking to its vicinity by vacuum electromagnetic fluctuations. Here, we show that vacuum quantum fluctuations proximate to a parity-symmetry-broken material can induce a…

Quantum Physics · Physics 2023-12-01 Yanzhe Ke , Zhigang Song , Qing-Dong Jiang

Diffusion effect on chirality selection in a two-dimensional reaction-diffusion model is studied by the Monte Carlo simulation. The model consists of achiral reactants A which turn into either of the chiral products, R or S, in a solvent of…

Statistical Mechanics · Physics 2007-07-20 Ryo Shibata , Yukio Saito , Hiroyuki Hyuga

The homochirality of biomolecules remains one of the outstanding puzzles concerning the beginning of life. Chiral amplification of a randomly perturbed racemic mixture of chiral molecules is a well-accepted prerequisite for all routes to…

Chemical Physics · Physics 2022-10-12 Uri Hananel , Assaf Ben-Moshe , Haim Diamant , Gil Markovich

We investigate the possibility that prebiotic homochirality can be achieved exclusively through chiral-selective reaction rate parameters without any other explicit mechanism for chiral bias. Specifically, we examine an open network of…

Biomolecules · Quantitative Biology 2015-06-03 Marcelo Gleiser , Bradley J. Nelson , Sara Imari Walker

A generalized autocatalytic model for chiral polymerization is investigated in detail. Apart from enantiomeric cross-inhibition, the model allows for the autogenic (non-catalytic) formation of left and right-handed monomers from a substrate…

Biomolecules · Quantitative Biology 2008-07-24 Marcelo Gleiser , Sara Imari Walker

Applying the constraints dictated by the principle of detailed balance, we analyze a recent proposal for spontaneous mirror symmetry breaking (SMSB) based on enantioselective autocatalysis coupled to a linear decay of the enantiomers and in…

Populations and Evolution · Quantitative Biology 2016-08-22 Michael Stich , Josep M. Ribó , David Hochberg

The observed single-handedness of biological amino acids and sugars has long been attributed to autocatalysis. However, the stability of homochiral states in deterministic autocatalytic systems relies on cross inhibition of the two chiral…

Populations and Evolution · Quantitative Biology 2015-10-14 Farshid Jafarpour , Tommaso Biancalani , Nigel Goldenfeld

To understand the effects of fluctuations on achieving homochirality, we employ a Monte-Carlo method where autocatalysis and enantiomeric cross-inhibition, as well as racemization and deracemization reactions are included. The results of…

Biomolecules · Quantitative Biology 2019-08-26 Axel Brandenburg

We consider the APED model (activation-polymerization-epimerization-depolymerization) for describing the emergence of chiral solutions within a non-catalytic framework for chiral polymerization. The minimal APED model for dimerization can…

Chemical Physics · Physics 2012-10-09 Michael Stich , Celia Blanco , David Hochberg

Given any finite and closed chemical reaction system, it is possible to efficiently determine whether or not it contains a `self-sustaining and collectively autocatalytic' subset of reactions, and to find such subsets when they exist.…

Molecular Networks · Quantitative Biology 2015-01-26 Mike Steel

The stability and conservation properties of a recently proposed polymerization model are studied. The achiral (racemic) solution is linearly unstable once the relevant control parameter (here the fidelity of the catalyst) exceeds a…

Biomolecules · Quantitative Biology 2007-05-23 A. Brandenburg , A. C. Andersen , S. Höfner , M. Nilsson

Biological systems exhibit marked molecular asymmetry, with proteins based predominantly on L-amino acids and nucleic acids and carbohydrates largely composed of D-sugars. Explanations for homochirality include asymmetric photochemistry,…

Other Quantitative Biology · Quantitative Biology 2026-05-26 Arturo Tozzi
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